- Neuroscience of respiration and sleep
- High Altitude and Hypoxia
- Heart Rate Variability and Autonomic Control
- Cardiovascular and exercise physiology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Cardiac Health and Mental Health
- Physical Activity and Health
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Ion channel regulation and function
- Cardiovascular Effects of Exercise
- Atomic and Subatomic Physics Research
- Exercise and Physiological Responses
- Pediatric Hepatobiliary Diseases and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Suicide and Self-Harm Studies
- Cancer-related molecular mechanisms research
- Workplace Health and Well-being
- Health, psychology, and well-being
- Receptor Mechanisms and Signaling
- Hemoglobinopathies and Related Disorders
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Karl Landsteiner University of Health Sciences
2016-2024
MaineHealth
2024
Maine Medical Center
2024
Universitätsklinikum Krems
2016-2020
Cornell University
2020
State Institution "Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of Ministry of Health of Ukraine"
2012
University of California, San Diego
1993-2001
University of Vienna
1992-1999
American College of Surgeons
1997
University of California, San Francisco
1996
Background High concentrations of inspired oxygen are associated with pulmonary atelectasis but also provide recognized advantages. Consequently, the appropriate concentration for general surgical use remains controversial. The authors tested hypothesis that and dysfunction on first postoperative day comparable in patients given 30% or 80% perioperative oxygen. Methods Thirty aged 18-65 yr were anesthetized isoflurane randomly assigned to during 2 h after colon resection. Chest radiographs...
We tested the hypothesis that unanesthetized rats exhibit ventilatory long-term facilitation (LTF) after intermittent, but not continuous, hypoxia. Minute ventilation (V˙e) and carbon dioxide production (V˙co 2 ) were measured in unanesthetized, unrestrained male Sprague-Dawley via barometric plethysmography before, during, exposure to continuous or intermittent Hypoxia was either isocapnic [inspired O fraction (Fi = 0.08–0.09 inspired CO 0.04] poikilocapnic 0.11 Fi 0.00). Sixty minutes...
Individuals with a prior history of (susceptible to high altitude pulmonary edema (HAPE-S) have resting arterial pressures, but little data are available on their vascular response exercise. We studied the exercise in seven HAPE-S and nine control subjects at sea level 3,810 m altitude. At each location, both normoxic (inspired PO2 = 148 Torr) hypoxic 91 studies were conducted. Pulmonary hemodynamic measurements included occlusion pressures. A multiple regression analysis demonstrated that...
Ventilation-perfusion (VA/Q) mismatch has been shown to increase during exercise, especially in hypoxia. A possible explanation is subclinical interstitial edema due high pulmonary capillary pressures. We hypothesized that this may be pathogenetically similar high-altitude (HAPE) so HAPE-susceptible people with higher vascular pressures would develop more exercise-induced VA/Q mismatch. To examine this, seven healthy a history of HAPE and nine altitude exposure but no (control) were studied...
Cardiac rehabilitation (CR) is a key component of the treatment cardiac diseases. The Austrian outpatient CR model unique, as it provides patients with an extended professionally supervised, multidisciplinary program 4-6 weeks phase II (OUT-II) and 6-12 months III (OUT-III) CR. aim this analysis was to assess efficacy using nationwide registry.Data all consecutive (N = 7560) who completed OUT-II and/or OUT-III between 1 January 2005 31 December 2015 were entered prospectively into registry....
Reports of acute mountain sickness (AMS) at moderate altitude show a wide variability, possibly because different investigation methods. The aim our study was to investigate the impact methods on AMS incidence. Hackett's established score (a structured interview and physical examination), new Lake Louise self-reported questionnaire) oxygen saturation were determined in 99 alpinists after ascent 2.94 km altitude. incidence 8% 25% score. Oxygen correlated inversely with no significant...
Magnetic resonance imaging was used to assess the effects of ventilation with positive end-expiratory pressure (PEEP) on cardiac volumes, especially atrial volumes as well determine semiquantitative measurements spatial interactions between heart, lungs and chest.Prospective study healthy volunteers undergoing mechanical different levels PEEP during magnetic imaging.Magnetic unit, Institute Diagnostic Imaging, Rudolfinerhaus Hospital.Twelve volunteers.Volunteers were imaged, using a...
Cardiac rehabilitation (CR) patients often do not sustain physical activity (PA) behaviour in the long run, once they progress into a self-management stage of secondary prevention. This study aimed to explore former CR patients' PA preferences, determinants (i.e., influencing factors) and motivation for sustained engagement. We conducted cross-sectional multi-centre survey using an original questionnaire based on prior qualitative interviews with cardiac patients. Five centres Austria posted...
Perfluorocarbon emulsions raise blood O2 solubility and thus augment transport, but their cardiopulmonary effects at higher doses may limit use. We therefore examined of increasing perfluorooctylbromide emulsion (Oxy) on 1) pulmonary gas exchange, 2) systemic hemodynamics, 3) mixed venous PO2 (PVO2). After hematocrit reduction to 24–26% by exchange with 5% albumin, anesthetized ventilated dogs breathing 100% were given Oxy (n = 6) or albumin 5) intravenously in four successive 3 ml/kg doses....
To assess the influence of different positive end-expiratory pressure (PEEP) levels on plasma atrial natriuretic peptide concentrations.Prospective, randomized study.Intensive care unit a university hospital.Twenty-seven patients who were mechanically ventilated due to acute respiratory failure.None.The into three groups: in each group, defined PEEP level (5, 10, or 15 cm H2O, respectively) was applied, alternating with zero (0 H2O) consecutive order (reversal experiment). Blood samples for...
Objective Digital health technologies offer great potential to improve access and adherence cardiovascular disease secondary prevention measures such as regular physical activity (PA). However, the use perceptions of digital technology (DT) among cardiac rehabilitation (CR) patients are not well understood. The aim this study was therefore explore DT in former CR patients’ daily lives, for PA information; gain insight into patient PA, including barriers, facilitators requested features....
Terbutaline, a β2-adrenergic agonist, has been shown to cause hypokalemia and an increase of plasma glucose serum insulin concentrations. We considered that terbutaline-induced may be due the insulin-induced shift potassium (K+) from extracellular intracellular space. If so, then inhibition secretion by somatostatin would prevent hypokalemia. Further, we wondered whether oral pretreatment could Therefore, 10 healthy volunteers (5 men, 5 women; mean age, 23 yr ± 3 SD) received either sodium...
Introduction: In response to increasing suicide rates among youth, further focus has been put on screening for and associated risk factors across health care settings. A frequent approach rely depression as the only factor part of process. Adolescents admitted inpatient pediatrics have an inherently higher given their medical comorbidities, available literature shown that focusing symptoms is inadequate.
The aim of this study is to examine the association between symptoms stress-tension, depression and anxiety hypertension status. In studu were used next questionnaires Determination nervous mental strain ( by T. Nemchin, 1988), scale PSM-25 Lemyr-Tessier-Fillion-, 1983), Method for determining stress-tndurance social adaptation (by Holmes Rage, 1995) Boston stres -endurance test, evaluation stress Kouhen, 1995), Beck (BDI) , self-test hypochondria Wilson test ), exhaustion vitality Appels )...
Lipids, lipoproteins, apolipoproteins and prostacyclin-half-life (PGI2-T/2) in vitro were determined patients, who suffered from severe circulatory shock. Extremely lowered lipids, lipoproteins an extremely shortened PGI2-T/2 found, these patients. These findings support the data of Yui Aoyama that may be important coregulator biological half-life PGI2 thereby contribute to hemostatic dyregulation seen