A5012447112- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Tissue Engineering and Regenerative Medicine
- Histone Deacetylase Inhibitors Research
- Testicular diseases and treatments
- Sarcoma Diagnosis and Treatment
- Cancer-related gene regulation
Zhejiang Chinese Medical University
2023-2024
First Affiliated Hospital of Nanchang University
2017
Nanchang University
2017
MicroRNAs are small non-coding RNAs, which critical regulators of carcinogenesis and tumor progression. Previous studies have identified that microRNA-20b (miR-20b) acts as an oncogene in numerous cancers. However, the role miR-20b prostate cancer remains unclear. The present study aimed to investigate expression examine whether modulating impacts cellular proliferation migration. It was revealed strongly expressed tissues compared with adjacent normal (P<0.05). Knockdown by inhibitor...
The regulation of initiation and progression during carcinogenesis bladder carcinoma is not completely elucidated. Dysregulation microRNAs has been detected to play critical roles in the development various cancers, including carcinoma, whereas involvement miR-223-3p tumorigenesis studied. Here, we show that significantly higher levels nuclear receptor coactivator 1 lower were tissue, compared adjacent non-tumor tissue. In addition, inversely correlated. Moreover, low specimens associated...
The previous study has proved the oncogenic role of Yes-associated protein 1 (YAP1) in bladder cancer (BLCA), thus this focused on its impact stem cells (BCSCs) and underlying mechanism.
In recent years, there has been growing evidence linking mitochondrial dysfunction to the development and progression of cancer. However, role metabolism-related genes (MMRGs) in testicular germ cell tumor (TGCT) remains unclear. We downloaded clinical pathology, transcriptome, somatic mutation data for TGCT from public databases conducted univariate Cox regression analysis investigate prognostic correlations. also used consensus clustering identify molecular subtypes, comparing differential...