A5018005003- Cancer Treatment and Pharmacology
- Head and Neck Cancer Studies
- Multiple Myeloma Research and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Chemotherapy-related skin toxicity
- Estrogen and related hormone effects
- Cancer Genomics and Diagnostics
- Colorectal and Anal Carcinomas
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Pancreatic and Hepatic Oncology Research
- Protein Degradation and Inhibitors
- Pain Mechanisms and Treatments
- Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Menopause: Health Impacts and Treatments
- Plant-based Medicinal Research
- Colorectal Cancer Treatments and Studies
- Breast Cancer Treatment Studies
- PARP inhibition in cancer therapy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Oral health in cancer treatment
- Contact Dermatitis and Allergies
- Cancer Cells and Metastasis
Mayo Clinic
2015-2021
Mayo Clinic in Arizona
2015-2020
University of Virginia
2012-2017
WinnMed
2015
Marymount University
2015
There is a concern that influenza vaccination could increase the incidence of immune-related adverse events (irAEs) in patients with cancer receiving immune checkpoint inhibitors. The aim our study was to determine safety this patient population.
Over the past decade, use of novel agents, including immunomodulatory drugs (IMiDs) and proteasome inhibitors (PIs) has resulted in high response rates improvement overall survival (OS) for patients with multiple myeloma (MM); however, prognostic significance refractoriness to these agents when used as initial therapy not been extensively studied. We reviewed outcomes 816 consecutive treated MM at our institution since 2006 evaluate difference between those achieving least a partial (PR)...
<h3>Importance</h3> The prognostic significance of p16 in squamous cell carcinoma (SCC) the hypopharynx (HP) and nasopharynx (NP) relationship between human papillomavirus (HPV) is unclear. <h3>Objectives</h3> To evaluate pharyngeal subsites (oropharynx [OP], HP, NP) assess HPV HP NP. <h3>Design, Setting, Participants</h3> Retrospective medical record review 172 patients with SCC pharynx treated definitive radiation therapy from 2002 to 2013 at a university tertiary referral center, tissue...
4108 Background: Availability of cancer gene mutation panel-based screening will identify increasing numbers patients who carry diverse germline mutations. Prevalence mutations and survival by carrier status among PDAC has not been well described. Methods: Using a hereditary panel, we sequenced 25 susceptibility genes in lymphocyte DNA from 303 well-characterized (47% female, mean age (+SD) 64.9+10.3 years, 98% White, 3% Ashkenazi Jewish heritage) the Mayo Clinic Familial Pancreatic Cancer...
Background: We analyzed the pattern of distant metastasis (DM) and secondary primary cancers (SPC) in patients with oropharyngeal squamous cell carcinoma (OPSCC) to develop surveillance guidelines. Methods: A retrospective review 177 OPSCC treated intensity modulated radiation therapy ± chemotherapy between 2002 2012 was performed characterize rate, pattern, timing DM SPC. Results: Sixteen (9.0%) developed 9 (5.1%) a Overall, 24/177 (13.6%) and/or SPC for total 27 events. 92.6% (25/27)...
e21054 Background: Up to 50% of patients undergoing resection for advanced melanoma experience recurrence. Identification preoperative prognostic biomarkers is needed ascertain risk relapse and guide postoperative management. Lactate dehydrogenase (LDH) represents a strong factor in unresectable metastatic (stage IV) melanoma, but its relevance with resected stage III or IV disease remains unknown. Methods: We retrospectively analyzed data from who had undergone complete received follow-up...
10016 Background: Pilot data support that Scrambler therapy may benefit patients with Chemotherapy-induced peripheral neuropathy (CIPN). Methods: Patients CIPN for at least 3 months were eligible if the patient had finished previous neurotoxic chemotherapy. They needed to have CIPN-related tingling or pain of 4/10 during week prior registration. randomized receive versus TENS (trans-electrical nerve stimulation), 2 weeks. Patient- reported outcomes utilized, including EORTC 20 instrument,...
Among the most debilitating of chemotherapy-related toxicities is neuropathy, which associated with several commonly used oncologic agents. The specific characteristics neurotoxicity vary between inciting drugs, important differences in symptom and clinical course. No medications have been found to effectively prevent chemotherapy-induced investigations predictors severe date explain only a small part susceptibility (making it difficult tailor chemotherapies individual risk). Treatment has...