A5100419336- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Lung Cancer Research Studies
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Enhanced Recovery After Surgery
- Lung Cancer Treatments and Mutations
- Dysphagia Assessment and Management
- Gastroesophageal reflux and treatments
- Intraperitoneal and Appendiceal Malignancies
- Esophageal and GI Pathology
- Anorectal Disease Treatments and Outcomes
- RNA modifications and cancer
- Radiomics and Machine Learning in Medical Imaging
- Stoma care and complications
Second Affiliated Hospital of Nanchang University
2025
Nanchang University
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2024
Peking University Cancer Hospital
2024
Peking University
2024
Academy of Medical Sciences
2019
Academia Sinica
2019
Peking Union Medical College Hospital
2016
There is no recognized biomarker recommended to monitor or predict the prognosis of colorectal cancer (CRC) patients with negative detection carcinoembryonic antigen (CEA) carbohydrate 19-9 (CA19-9) and classify high recurrence-risk cases. Discovery two-stage validation cohorts, which included 2111 radically resected stage II-III CRC, were enrolled in this study. We detected preoperative peripheral monocyte, platelet, albumin (Alb), pre-albumin (pAlb), CEA, CA19-9 investigated prognostic...
Colorectal cancer is a common digestive worldwide. As comprehensive treatment for locally advanced rectal (LARC), neoadjuvant therapy (NT) has been increasingly used as the standard clinical stage II/III cancer. However, few patients achieve complete pathological response, and most require surgical resection adjuvant therapy. Therefore, identifying risk factors developing accurate models to predict prognosis of LARC are great significance.To establish effective prognostic nomograms score...
Background Epidemiologically, in China, locally advanced rectal cancer is a more common form of cancer. Preoperative neoadjuvant concurrent chemoradiotherapy can effectively reduce the size invasive tumors and improve disease-free survival (DFS) pathologic response after surgery. At present, this modality has become standard protocol for treatment many centers, but optimal time surgery therapy still controversial. Aim To investigate impact interval between on DFS patients with Methods A...
Colorectal high-grade neuroendocrine neoplasms (HGNENs) are rare and constitute less than 1% of all colorectal malignancies. Based on their morphological differentiation proliferation identity, these present heterogeneous clinicopathologic features. Opinions regarding treatment strategies for improvement the clinical outcomes patients remain controversial.To delineate features explore prognostic factors this malignancy.This observational study reviewed data 72 consecutive with HGNENs from...
Abstract Background It is gradually accepted that solid bolus swallow needs to be added the procedure of manometry. The motility differences in upper esophageal sphincter ( UES ) and lower LES were not well described. Sierra Scientific Instruments solid‐state high‐resolution manometry HRM system, most popular system China, lacks Chinese normative values for both liquid parameters. Methods data 88 healthy volunteers analyzed. parameters sphincters resting stage summarized those during...
Xiao Meng, Jie Wang, Jianming Ying, Meiling Wu, Cui Qian, Zhijie Qian
Anastomotic leakage (AL) is a common and devastating postoperative issue for patients who have undergone anterior resection of rectal carcinoma can lead to increased short-term morbidity mortality. Moreover, it might be associated with worse oncological prognosis tumors. This study aimed at exploring the risk factors symptomatic AL after laparoscopic (LAR) tumors without preventive diverting stoma. case control retrospectively reviewed data 496 consecutive underwent LAR rectum stoma Cancer...
Intraoperative intraperitoneal chemotherapy is an emerging treatment modality for locally advanced rectal neoplasms. However, its impacts on postoperative complications remain unknown. Anastomotic leakage (AL) one of the most common and serious associated with anterior resection tumors. Therefore, we designed this study to determine effects intraoperative AL.To investigate whether increases incidence AL after neoplasms.This retrospective cohort collected information from 477 consecutive...
Natural orifice specimen extraction surgery (NOSES) has been confirmed as an alternative approach without auxiliary incisions. The purpose of this study was to investigate the short-term and survival outcomes NOSES versus conventional laparoscopic (LAP) in treatment sigmoid high rectal cancer. retrospective conducted at single centers between January 2017 December 2021. Relevant data included clinical demographics, pathological features, operative parameters, postoperative complications were...
For the management of lateral lymph node (LLN) metastasis in patients with rectal cancer, selective LLN dissection (LLND) is gradually being accepted by Chinese scholars. Theoretically, fascia-oriented LLND allows radical tumor resection and protects organ function. However, there a lack studies comparing efficacy traditional vessel-oriented LLND. Through preliminary study small sample size, we found that was associated lower incidence postoperative urinary male sexual dysfunction higher...
BACKGROUNDConventional clinical guidelines recommend that at least 12 lymph nodes should be removed during radical rectal cancer surgery to achieve accurate staging.The current application of neoadjuvant therapy has changed the number node dissection. AIMTo investigate factors affecting dissected after chemoradiotherapy in locally advanced and evaluate relationship total retrieved (TLN) with diseasefree survival (DFS) overall (OS). METHODSA 231 patients from 2015 2017 were included this...
Purpose. Colorectal neuroendocrine neoplasms (NENs) are rare tumors. The prognosis and prognostic factors of metastatic colorectal NENs have not been fully elucidated. Methods. We retrospectively enrolled 77 consecutive patients diagnosed with synchronous distant metastases between 2000 2021. All were assigned to the tumor (NET) group or carcinoma (NEC) based on histological differentiation. Propensity score matching (PSM) was performed minimize confounding bias. Kaplan–Meier method used...