A5065811941- Bone fractures and treatments
- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Spinal Fractures and Fixation Techniques
- Total Knee Arthroplasty Outcomes
- Scoliosis diagnosis and treatment
- Injury Epidemiology and Prevention
- Foot and Ankle Surgery
- Spine and Intervertebral Disc Pathology
- Trauma Management and Diagnosis
- Hip disorders and treatments
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Pelvic and Acetabular Injuries
- Medical Imaging and Analysis
- Sports injuries and prevention
- Diversity and Career in Medicine
- Hip and Femur Fractures
- Diabetic Foot Ulcer Assessment and Management
- Innovations in Medical Education
- Ferroptosis and cancer prognosis
- Cancer Mechanisms and Therapy
- Lower Extremity Biomechanics and Pathologies
- Nursing Education, Practice, and Leadership
- Surgical Simulation and Training
Temple University Hospital
2023-2025
Temple University
2024
Children's Hospital of Philadelphia
2019-2023
University of Toledo
2018-2021
Children's Hospital of San Antonio
2020
Johns Hopkins Children's Center
2019
Johns Hopkins University
2019
Children's Mercy Hospital
2019
University of Toledo Medical Center
2018
Creative Research Enterprises (United States)
2018
Effective management of advanced cancer requires systemic treatment including small molecules that target unique features aggressive tumor cells. At the same time, tumors are heterogeneous and current evidence suggests a subpopulation cells, called initiating or stem responsible for metastatic dissemination, relapse possibly drug resistance. Classical apoptotic drugs less effective against this critical subpopulation. In course generating library open-chain epothilones, we discovered new...
To analyze the literature on efficacy of dynamamization vs exchange nailing in treatment delayed and non-union femur fractures.Ultimately, 31 peer-reviewed articles with 644 exchanged patients 131 dynamization were identified analyzed. The following key words inputted different combinations order to search field publications its entirety: "non-union", "delayed union", "ununited", "femur fracture", "femoral "exchange nailing", "dynaiz(s)ation", "secondary "dynamic", "static", "nail revision"....
Study Design. Retrospective cohort study. Objective. To evaluate the outcomes and reoperation rates in patients with adolescent idiopathic scoliosis undergoing lumbar anterior vertebral body tethering (AVBT). Background. AVBT is a viable option for growing children. The benefit of motion preservation must be balanced by higher rate. A paucity reports has addressed AVBT. Materials Methods. single-center retrospective study was conducted to identify all who underwent (lowest instrumented...
In the course of generating a library open-chain epothilones, we discovered new class small molecule anticancer agents that has no effect on tubulin but instead kills selected cancer cell lines by harnessing reactive oxygen species in an iron-dependent manner.
There remains a paucity of data regarding long-term patient-reported outcomes following Lisfranc injuries. We sought to collect clinical outcome injuries using PROMIS Physical Function (PROMIS-PF) and visual analog scale-foot ankle (VAS-FA).A chart review was performed identify all patients who had surgical treatment an acute injury at our institution from 2005 2014. Of the 45 identified, we were able recruit 19 for follow-up clinic visit consisting physical examination, administration...
Subtalar dislocations are rare injuries that typically occur from high-energy injuries.All subtalar should be attempted to closed reduced, however, ~32% irreducible requiring open reduction.We present an medial dislocation following a motor vehicle accident with no associated fractures demonstrated on radiograph.However, reduction revealed incarcerated anterior talar head fracture was reduced and stabilized retrograde K-wires.
Introduction: Thyroid disorders are increasingly prevalent, with a higher incidence in women, particularly postmenopausal women. Symptoms of menopause, such as irritability, hot flushes, fatigue, and weight gain, often overlap those thyroid dysfunction, complicating diagnosis. Identifying dysfunction this population is crucial for improving their overall health preventing complications like cardiovascular diseases, which associated untreated disorders. Methodology: A hospital-based,...
This allows for blended learning and flipped classroom opportunities the reduced in-person didactic time that orthopaedic surgical faculty have with residents today. Exam preparation Orthopaedic In-Training (OITE) American Board of Surgeons (ABOS) is now very commonly done online platforms. Journal club activities also shifted to virtual space; podcasts provide a new way learn when on go, augmented reality technologies are starting make their into training. Evidence these methods steadily...
We sought to determine whether significantly displaced Lisfranc injuries had a higher rate of loss reduction after fixation compared those with low displacement. Forty-five patients who an acute injury from 2005 2014 were retrospectively reviewed. All underwent subsequent hardware removal at 3 15 months their index procedure. Radiographs reviewed the time injury, 2 weeks, and 6 postoperative. joint was assessed using criteria previously described in literature graded as malreduced if...
Fractures about the tibial tubercle are uncommon fracture patterns, seen most often in adolescent males as they approach skeletal maturity. Compartment syndrome has a high association with these fractures requiring close monitoring, and heightened level of suspicion. Tibial typically stratified using Ogden classification. The type intra-articular involvement degree displacement guide appropriate treatment. This report highlights 14-year-old male patient who suffered IV unique Salter-Harris...
Introduction: Although the American Academy of Orthopaedic Surgery, Pediatrics, and Pediatric Orthopedic Society North America have established lawnmower safety guidelines, a notable number injuries continue to occur. We sought elaborate on epidemiology in pediatric age group compare urban versus rural injuries. Methods: The Health Information System database was queried for patients 1 18 years from 2005 2017 who presented with injury. Results were computed using bivariate tests multinomial...
Background: Patients with cerebral palsy scoliosis (CPS) experience higher complication rates compared idiopathic and often present for surgery larger curves. Prediction of an inflection point rapid deformity progression has proven difficult. A proximal humerus-based skeletal maturity staging system (HS) been recently validated is commonly visible on the posteroanterior radiograph. The authors hypothesize that this can be used to identify a period at which CPS may progress rapidly, perhaps...
Objectives Recreational swimming/diving is among the most common physical activities in US children and a significant cause of morbidity across United States. This study updates national epidemiology diving-related injuries. Methods The Consumer Product Safety Commission's National Electronic Injury Surveillance System database was queried for patients aged 0 to 19 from 2008 2020 who presented any 100 System-participating emergency departments injury. Dive characteristics such as dive...