A5058637324- Biomedical and Engineering Education
- Anatomy and Medical Technology
- Surgical Simulation and Training
- Spinal Fractures and Fixation Techniques
- 3D Printing in Biomedical Research
- Bone and Joint Diseases
- Bone Tissue Engineering Materials
- Cardiac and Coronary Surgery Techniques
- Scoliosis diagnosis and treatment
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Eosinophilic Esophagitis
- Orthopedic Surgery and Rehabilitation
- Management of metastatic bone disease
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular and Diving-Related Complications
- Gastroesophageal reflux and treatments
- Bone health and treatments
- Bone health and osteoporosis research
- Silk-based biomaterials and applications
- Musculoskeletal Disorders and Rehabilitation
- Congenital Heart Disease Studies
- Spine and Intervertebral Disc Pathology
- Obstructive Sleep Apnea Research
- Acute Ischemic Stroke Management
Shriners Hospitals for Children - Philadelphia
2017-2023
Shriners Hospitals for Children
2023
Einstein Medical Center Philadelphia
2008-2018
Yeshiva University
2011
Drexel University
2008
The use of intraoperative fluoroscopy has become a routine and useful adjunct within orthopaedic surgery. However, the machine may an additional source contamination in operating room, particularly when maneuvering from anterior-posterior position to lateral position. Consequently, draping techniques were developed maintain sterility operative field surgeon. Despite variety methods, no studies exist compare these specifically is imaging We evaluated 3 c-arm simulated environment. consisted...
Magnetically controlled growing rods (MCGRs) are an effective alternative to traditional (TGRs) in the treatment of early-onset scoliosis (EOS), with comparable deformity correction despite fewer planned reoperations. This case report presents a unique autofusion patient tetraplegic cerebral palsy, thoracic myelomeningocele, and EOS who was treated dual MCGR instrumentation underwent serial lengthening procedures for four years. We detail operative radiographic findings novel encountered...
Chemotherapeutic bone cements can both stabilize the fractures as well deliver chemotherapy agents directly to metastatic site and adjacent soft tissue tumors. This study evaluated in vitro elution flexural properties of Vertebroplastic™ Confidence Ultra™ (Depuy Spine Inc., Raynham, Mass., USA) containing methotrexate. In was measured by placing cement specimens 4 different methotrexate amounts 20 ml saline, at regular intervals for 672 h. The 2 initial after storage physiological saline...
Statins are known to inhibit growth of a number cancer cells, but their mechanism action is not well established. In this study, human prostate adenocarcinoma PC-3 and breast MCF-7 cell lines were used as models investigate the atorvastatin, one statins. Atorvastatin was found induce apoptosis in cells at concentration 1 μM, 50 μM. Initial survey possible pathway using various pathway-specific luciferase reporter assays showed that atorvastatin-activated antioxidant response element (ARE),...
Abstract Osteoporosis (“secondary” osteoporosis) and avascular necrosis (AVN) of the femoral head are well‐known adverse effects corticosteroid therapy. Statins have been reputed to increase bone strength density. In this study, we evaluated effect atorvastatin calcium on flexural properties (3‐point bending modulus) (methylprednisolone acetate) treated rabbit femurs tibias. Our study hypothesis was that use statins would counteract loss caused by treatment. The 40 rabbits were divided into...
The aim of our study was to characterize jackhammer esophagus symptoms and their relationship with the distal contractile integral (DCI) bolus transit.Jackhammer is defined by Chicago Classification version 3.0. This diagnosis relatively new, most current definition being established in 2014. forerunners this diagnosis, nutcracker (or hypercontractile) esophagus, have been associated noncardiac chest pain (NCCP).A retrospective chart review performed motility studies from 2011 2016. Studies...
Study Design. Retrospective cohort study. Objective. To evaluate the outcomes and reoperation rates in patients with adolescent idiopathic scoliosis undergoing lumbar anterior vertebral body tethering (AVBT). Background. AVBT is a viable option for growing children. The benefit of motion preservation must be balanced by higher rate. A paucity reports has addressed AVBT. Materials Methods. single-center retrospective study was conducted to identify all who underwent (lowest instrumented...
Carotid artery stenting (CAS) has been associated with increased periprocedural stroke in comparison carotid endarterectomy (CEA). Three-dimensional (3D) printing of aortic arch and may aid preprocedural planning adaptive learning, possibly reducing procedure-related complications.Five CAS cases available computed tomography angiography (CTA) were retrospectively evaluated 3D-printed models (3D-PMs) made. One additional case that was 3D printed preprocedurally provided prospective analysis....
Cerebral Palsy (CP), the most common cause of disability in children, is phenotypically heterogeneous. Approximately 20% cases develop severe scoliosis. A pathological hallmark CP periventricular leukomalacia (PVL), which due to dysmyelination, suggesting possibility a lipidomic abnormality. Risk factors for include perinatal hypoxia, prematurity, multiple gestation, ischemia, infection, and maternal alcohol consumption. There evidence low serum levels omega-3 (ω-3) fatty acids patients,...
Objective Obstructive sleep apnoea (OSA) is strongly associated with cardiovascular disease. However, acute effects of repetitive airway obstruction are poorly understood. While past research used a sustained Mueller manoeuver to simulate OSA we employed series gasping efforts better true obstructive apnoeas. This report describes changes in cardiac anatomy and flow related sudden intrathoracic pressure. Methods results 26 healthy, normal weight participants performed 5–6 (target pressure...
Background In severely osteoporotic proximal humerus fractures, the biomechanics of fixed-angle fracture fixation with locked smooth pegs may be improved by using polymethyl methacrylate (PMMA) augmentation. Commercially available were modified (added a central cannula and two distal side ports) to accommodate bone cement injection around pegs. The failure strength stiffness PMMA augmentation was evaluated. Methods Nineteen fresh-frozen cadaveric humeri fixated plate using: (i) (seven...