A5064127312- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Hemodynamic Monitoring and Therapy
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Lipoproteins and Cardiovascular Health
- Cardiac Valve Diseases and Treatments
- Non-Invasive Vital Sign Monitoring
- Tissue Engineering and Regenerative Medicine
- Cardiac electrophysiology and arrhythmias
- Antiplatelet Therapy and Cardiovascular Diseases
- Advanced MRI Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Mesenchymal stem cell research
- Cardiac Arrhythmias and Treatments
- Cell Adhesion Molecules Research
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Dermatologic Treatments and Research
- Advanced X-ray and CT Imaging
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
University of California, Los Angeles
1994-2020
Cedars-Sinai Smidt Heart Institute
2010-2020
Cedars-Sinai Medical Center
2007-2019
Cleveland Clinic
1999-2017
Duke University Hospital
2017
Duke Medical Center
2017
Clinical Research Institute
2017
Mayo Clinic in Arizona
2017
Columbia University Irving Medical Center
2017
Heart Hospital Baylor Plano
2017
The diagnosis of coronary-artery disease has become increasingly complex. Many different results, obtained from tests with substantial imperfections, must be integrated into a diagnostic conclusion about the probability in given patient. To approach this problem practical manner, we reviewed literature to estimate pretest likelihood (defined by age, sex and symptoms) sensitivity specificity four tests: stress electrocardiography, cardiokymography, thallium scintigraphy cardiac fluoroscopy....
Pressures in the right side of heart and pulmonary capillary wedge can be obtained by cardiac catheterization without aid fluoroscopy. A No. 5 Fr double-lumen catheter with a balloon just proximal to tip is inserted into atrium under pressure monitoring. The then inflated 0.8 ml air. carried blood flow through smaller radicles artery. In this position when obtained. average time for passage from artery was 35 seconds first 100 passages. frequency premature beats minimal, no other arrhythmias...
To visualize intracoronary lesions in patients with different clinical expressions of coronary disease, we performed angioscopy during coronary-artery bypass surgery 10 unstable angina and stable disease. We examined a total 32 vessels, using flexible fiberoptic angioscopes. Twenty-two vessels had no acute intimal lesion; three complex plaques, six thrombi, one both. Coronary angiography correctly identified the absence plaque thrombus 22 but it detected only four plaques seven thrombi. On...
In the broadest sense, current hospital therapy of acute myocardial infarction attempts to prevent, or promptly and effectively treat, electrical mechanical consequences regional ischemia infarction, while preserving jeopardized ischemic myocardium. Prevention effective arrhythmias have largely been realized through development coronary-care units. The goals prompt disordered cardiac function preservation muscle, although far from achieved, greatly advanced in past several years by...
Abstract Furosemide, 0.5 to 1.0 mg per kilogram intravenously, was given 20 patients with left ventricular failure after acute myocardial infarction. Within five 15 minutes, average filling pressure fell from 20.4 14.8 mm Hg, accompanied by a 52 cent increase in mean calf venous capacitance. During the same period there no physiologically important change either urine output or heart rate, blood and cardiac output. Peak flow (from of 0.82 4.0 ml minute) occurred at 30 peak natriuretic effect...
Hemodynamic effects of vasodilator therapy (phentolamine or nitroprusside) were studied in 38 patients with acute myocardial infarction (AMI). Cardiac metabolism was 19 the patients. According to initial level left ventricular filling pressure (LVFP) and stroke work index (SWI), divided into three groups: Group I-nine pa- tients LVFP 15 mm Hg less; II-14 > SWI >20 g-m/m 2 ; III-15 < 20 g-m/ m . In I most clinically uncomplicated. IL had clinical failure including one patient who...
The evaluation of left ventricular (LV) compliance by use the pressure-volume (P-V) relationship encounters several serious difficulties. Since P-V is curvilinear, it difficult to quantitate. Furthermore, alterations resting heart size and geometry also produce marked changes in curve. first derivative relationship, however, a precisely linear function expressed formula dP/dV = aP+b. slope this function, a, termed passive elastic modulus, has been shown be independent initial volume...
Although exercise radionuclide ventriculography was initially reported to be a highly specific test for coronary-artery disease, later studies high false-positive rate. To verify this turnabout, we analyzed the responses in 77 angiographically normal patients; 32 were studied from 1978 1979 (the early period), and 45 1980 1982 recent period). Most patients period had (94 per cent ejection fraction 84 wall motion). In contrast, less frequent (49 36 motion, P than 0.001). The probability of...
To assess the potential beneficial effects of vasodilator agents in patients with severe mitral regurgitation, sodium nitroprusside was administered intravenously at a rate 16 to 100 µg/min eight clinically significant regurgitation presumably due dysfunction subvalvar apparatus. In all there decrease magnitude peak `V' wave (from 50 ± 4.5 19 2.9 mm Hg) and left ventricular filling pressure (33 1.8 1.4 Hg), together decreased intensity apical pansystolic murmur. There increase forward...
A reproducible, noninvasive technique for determining right ventricular ejection fraction (RVEF) was developed using multiple-gated equilibrium blood pool scintigraphy, which allows serial rapid measurements without reinjection of radioactivity.Studies were obtained in vitro labeled technetium- 99m red cells, gamma camera and computer.In 20 patients, RVEF determined by imaging the left anterior oblique view compared with measured first-pass scin- tigraphy.For both types imaging, multiple...
Original Article from The New England Journal of Medicine — Filling Pressures in the Right and Left Sides Heart Acute Myocardial Infarction A Reappraisal Central-Venous-Pressure Monitoring