A5008366869- Hemodynamic Monitoring and Therapy
- Cardiac Imaging and Diagnostics
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Heart Rate Variability and Autonomic Control
- Cardiac Arrhythmias and Treatments
- Cardiovascular and Diving-Related Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac electrophysiology and arrhythmias
- Non-Invasive Vital Sign Monitoring
- Vascular anomalies and interventions
- Advanced MRI Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Acute Myocardial Infarction Research
- Cardiovascular and exercise physiology
- Ultrasound in Clinical Applications
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Cardiovascular Effects of Exercise
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Cardiac pacing and defibrillation studies
- Cardiovascular Conditions and Treatments
Walt Disney (United States)
2023
UCLA Health
2015
University of Minnesota
1952-2007
Princess Margaret Hospital for Children
2007
Thomas Swan (United Kingdom)
1975-2006
University of Helsinki
2005
Cedars-Sinai Medical Center
1982-1996
Royal Victoria Hospital
1993
University of California, Los Angeles
1975-1990
Pasadena City College
1985
Abstract Furosemide, 0.5 to 1.0 mg per kilogram intravenously, was given 20 patients with left ventricular failure after acute myocardial infarction. Within five 15 minutes, average filling pressure fell from 20.4 14.8 mm Hg, accompanied by a 52 cent increase in mean calf venous capacitance. During the same period there no physiologically important change either urine output or heart rate, blood and cardiac output. Peak flow (from of 0.82 4.0 ml minute) occurred at 30 peak natriuretic effect...
Hemodynamic effects of vasodilator therapy (phentolamine or nitroprusside) were studied in 38 patients with acute myocardial infarction (AMI). Cardiac metabolism was 19 the patients. According to initial level left ventricular filling pressure (LVFP) and stroke work index (SWI), divided into three groups: Group I-nine pa- tients LVFP 15 mm Hg less; II-14 > SWI >20 g-m/m 2 ; III-15 < 20 g-m/ m . In I most clinically uncomplicated. IL had clinical failure including one patient who...
To assess the potential beneficial effects of vasodilator agents in patients with severe mitral regurgitation, sodium nitroprusside was administered intravenously at a rate 16 to 100 µg/min eight clinically significant regurgitation presumably due dysfunction subvalvar apparatus. In all there decrease magnitude peak `V' wave (from 50 ± 4.5 19 2.9 mm Hg) and left ventricular filling pressure (33 1.8 1.4 Hg), together decreased intensity apical pansystolic murmur. There increase forward...
Analysis of multiple noninvasive tests offers the promise more accurate diagnosis coronary artery disease, but discordant test responses can occur frequently and, when observed, result in diagnostic uncertainty. Accordingly, 43 patients undergoing angiography were evaluated by testing and results subjected to analysis using Bayes' theorem conditional probability. The procedures used included electrocardiographic stress for detection exercise-induced ST segment depression, cardiokymographic...
Left ventricular (LV) pressure and myocardial segment length, determined by an epicardial mercury-in-silastic length gauge, were plotted simultaneously to obtain a pressure-length loop before after left anterior descending artery (LAD) occlusion in 11 dogs. Previous studies have indicated that the area within this is sensitive reproducible means of quantitating regional performance. Immediately following ligation, systolic performance deteriorated as progressive reduction area. Within...
In 10 normal dogs, the right and left ventricular volumes compliances were determined in fresh post-mortem heart. With use of a SigmaMotor pump, Ringer's solution at 23°C was simultaneously infused into both ventricles within an hour after death. When full but open to atmospheric pressure, mean 35.8 ml/m 2 for 23.1 ventricle; when transmural pressure increased by mm Hg, 56.9 41.9 20 values 60.8 48.5 , respectively. The initial increases volume produced increase affected position septum...
Thallium-201 (201Tl) redistribution scintigraphy might differentiate reversibly from nonreversibly asynergic myocardial segments and thus predict the response of these to coronary artery bypass grafting (CABG). To test this hypothesis, 25 consecutive patients undergoing CABG, preoperative stress-redistribution 201Tl scintigraphy, both pre- postoperative resting equilibrium radionuclide ventriculography were evaluated. For types scintigraphic study, each patient was imaged in same three...
The effect of valvular insufficiency on left ventricular volumes was studied by an angiographic method in 37 patients. Ejection the additional volume load imposed achieved increase end-diastolic and not increasing proportion ejected. Of patients, 16 (43 per cent) had a significant reduction fraction ejected beat. These patients performed significantly less stroke work from given fiber length (end-diastolic volume) than did others evidence is presented that they impaired myocardial function....
The cardiovascular response to angiographic contrast medium was studied in 28 patients undergoing diagnostic angiocardiography under anesthesia. A transient phase of hypotension and tachycardia similar that described by other authors noted. Cardiac output increased initially 50 per cent returned the base line 20 minutes. Peripheral blood flow 100 cent, apparently due direct effect hyperosmotic solution on vascular smooth muscle. Hemodilution, maximal 2 4 minutes after injection medium,...
Ventricular performance was assessed before and after angiocardiography in 22 patients with normal left ventricle, mitral stenosis, aortic myocardial disease. The increased circulating blood volume known to occur is a determinant of the ventricular pre-load. after-load unchanged. Patients ventricle some valve stenosis responded by an increase work performed had only minimal or no increase. A group serious heart disease less work. If response can be considered on basis Frank-Starling...
Kirklin, John W. M.D.; Donald, David E. B.V.S., M.R.C.V.S.; Harshbarger, Harry G. Hetzel, Peter S. M.D; Patrick, Robert T. Swan, H. J. C. M.B., M.R.C.P., Ph.D.; Wood, Earl M.D., Ph.D. Author Information
Evidence is presented which indicates that shunting of small amounts blood from right to left occurs frequently through interatrial communications. Such right-to-left shunts are magnitude in the usual case atrial septal defect, but it appears fractions shunted, a greater proportion has originated inferior vena cava than superior cava.
Use of cuvette and earpiece oximeters facilitates the recording immediate dilution pattern dye T-1824 (Evans blue) in arterial blood. In patients with venoarterial shunts curves differs from normal. Quantitative analysis such cyanotic congenital heart disease has been undertaken to establish proportion blood which bypassed pulmonary circulation. The results obtained have compared estimates volume shunt cardiac catheterization data related oxygen saturation.