A5071476921- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Salivary Gland Disorders and Functions
- Corneal Surgery and Treatments
- Allergic Rhinitis and Sensitization
- Ocular Diseases and Behçet’s Syndrome
- Retinal Diseases and Treatments
- Urticaria and Related Conditions
- Retinal and Optic Conditions
- Dermatologic Treatments and Research
- Acne and Rosacea Treatments and Effects
- Ophthalmology and Visual Impairment Studies
- Advanced Drug Delivery Systems
- Insect and Pesticide Research
- Advancements in Transdermal Drug Delivery
- Histiocytic Disorders and Treatments
- Mast cells and histamine
- Salivary Gland Tumors Diagnosis and Treatment
- Facial Rejuvenation and Surgery Techniques
- Bee Products Chemical Analysis
- Context-Aware Activity Recognition Systems
- Oral Health Pathology and Treatment
- Multiple Myeloma Research and Treatments
- Sinusitis and nasal conditions
Johns Hopkins Medicine
2016-2024
Johns Hopkins University
2016-2024
Johns Hopkins Hospital
2015
Istanbul Eye Hospital
2012-2013
To evaluate the refractive, topographic, optical, visual acuity, and quality outcomes of two types intrastromal corneal ring segments (ICRS) in treatment keratoconus.In this retrospective study, 16 eyes that had been implanted with Intacs ICRS (Addition Technology Inc) (Intacs group) 17 Ferrara (Ferrara Ophthalmics Ltda) were evaluated. Pre- postoperative examinations included uncorrected corrected distance acuities (UDVA CDVA, respectively), manifest refraction, slit-lamp examination,...
Patients with dry eye frequently report difficulty reading. However, the impact of on reading has not been studied in detail. This study shows unfavorable effect speed and offers mechanisms that may be responsible.The purpose this was to evaluate signs as well symptoms both short-duration out-loud prolonged silent reading.This included 116 patients clinically significant eye, 39 only, 31 controls, 50 years or older. After Ocular Surface Disease Index (OSDI) questionnaire, objective testing...
To evaluate the safety and efficacy of piggybacking with HumanOptics Add-On intraocular lens (IOL) to correct pseudophakic refractive errors.Ten eyes 10 patients errors were included in this study. All targeted for a range refraction -0.50 +0.50 D. Uncorrected corrected distance visual acuities (UDVA CDVA, respectively), endothelial cell count (ECC), anterior chamber depth (ACD), between lenses, contrast sensitivity measurements under mesopic, scotopic, scotopic glare conditions evaluated...
Purpose: Systemic implications necessitate the identification of dry eye patients with Sjögren syndrome (SS). This study aims to explore utility tear MUC5AC and inflammatory cytokine levels in differential diagnosis SS-related eye. Methods: A prospective, observational, case-control was conducted on 62 (those a definitive SS eye, non-SS age-matched healthy controls no eye). Clinical evaluations included following tests order listed here: noninvasive break-up time, osmolarity, sampling,...
Purpose: To analyze the distribution of tear film osmolarity in patients with dry eye and its association other ocular surface parameters. Methods: Tear quantitative parameters were obtained from 1) clinically significant (significant symptoms staining, n = 131), 2) symptoms-only but no 52), 3) controls (no or 42). Results: varied significantly across groups ( P 0.01), having highest (312.0 ± 16.9 mOsm/L), control lowest (305.6 9.7 falling between (307.4 5.6 mOsm/L). Patients also tended to...
Diagnostic criteria for monoclonal gammopathy of undetermined significance (MGUS) do not currently include ocular phenotypic changes. Here, we offer a new diagnostic approach that is useful in patients with posteriorly located corneal depositions and present evidence to support the theory aqueous humor source proteins accumulated cornea.A 77-year-old woman presented clinic gradual decrease visual acuity over 6 months. Slit lamp examination revealed bilateral central guttae consistent Fuchs...
To investigate the value of 3 novel autoantibodies [salivary protein 1 (SP1), carbonic anhydrase 6 (CA6), and parotid secretory (PSP)] in differentiating Sjögren's syndrome (SS)-related dry eye from non-SS eye.Forty-six patients with SS (SS eye), 14 without (non-SS 25 controls were included. The 2012 American College Rheumatology classification criteria used for diagnosis SS. After a detailed review systems, Ocular Surface Disease Index questionnaire, Schirmer test anesthesia, tear film...
Background . Diagnostic criteria for Sjögren’s syndrome (SS) are continually being updated in pursuit of more precise and earlier diagnosis to prevent its complications. Owing the high rate false negative traditional serological markers, need better testing remains. Objective To investigate clinical significance three recently discovered novel autoantibodies, anti-salivary gland protein 1 (SP1), anti-carbonic anhydrase 6 (CA6), anti-parotid secretory (PSP), a cohort dry eye patients with...
We evaluated the validity of a single dry eye severity measure estimated using Rasch analysis from battery clinical tests and patient symptoms.This study included 203 patients 51 controls. Administered Ocular Surface Disease Index (OSDI), tear osmolarity, Schirmer's test, noninvasive break-up time, ocular surface staining. Each 12 OSDI questions each test was defined to be separate indicator estimate analysis. Measures were for subject (person measures) measures sensitivity sign symptom...
To study the systemic safety and patient tolerability of frequent dosing cyclosporine A (CsA) 0.05% eyedrops in treatment ocular surface disease. This is a retrospective case series. Patients with significant diseases who were treated using topical CsA higher than usual twice daily (3-8 times over period 1-70 months). The main outcome measures are plasma levels local tolerability.Symptom assessment, corneal staining fluorescein, conjunctival lissamine green, tear film breakup time, other...
To report two patients with sarcoidosis initially presenting cicatrizing conjunctivitis.Both chronic conjunctivitis were referred for further management. The first patient had conjunctival granulomas, subepithelial fibrosis, and forniceal foreshortening. second extensive upper lower scarring foreshortening symblepharon formation of both eyes. Conjunctival biopsy specimens revealed noncaseating granulomas. Immunofluorescein studies negative immunoreactant deposition in the basement membrane....
To evaluate the clinical outcomes of using an Alcon intraocular lens (IOL) B cartridge for graft insertion during Descemet membrane endothelial keratoplasty (DMEK).We retrospectively reviewed medical charts patients who underwent DMEK Bonfadini-Todd injector, composed IOL connected to plastic tubing and a syringe, between May 2016 August 2018. Patient demographics, diagnoses, donor information, visual acuity, pressure (IOP), position attachment status, pachymetry, postoperative complications...
Purpose: To investigate the prevalence of SARS-CoV-2-associated conjunctivitis among patients presenting with to ophthalmology clinics in absence respiratory symptoms suggesting COVID-19 during first year pandemic. Patients and Methods: This prospective, observational, cross-sectional study enrolled aged 18 years older who presented acute between May 2020 2021. After reviewing demographics, ocular systemic symptoms, a slit lamp examination was performed. Five samples were collected...
In Descemet membrane endothelial keratoplasty (DMEK), loading and positioning of tri-folded grafts into a cartridge is generally conducted with forceps or hook, risking graft tear trauma. We demonstrate the feasibility no touch to endothelium required beyond tri-folding process.A corneoscleral rim prestripped DMEK placed petri dish. After removed from its stromal attachment, gently wicked tip saline-filled Alcon B IOL connected IV extension tubing 3 cc syringe, drawn by it adjacent tip. The...
Managing glaucoma after Boston type 1 keratoprosthesis (KPro) surgery remains challenging. We herein assessed the fitness of commonly used clinical tests to evaluate in KPro eyes versus with penetrating keratoplasty (PK) as controls.Sixteen patients and 14 PK tested an identical manner. After 10-2 visual field size V stimulus, intraocular pressure (IOP) was estimated palpation by first observer. Then, retinal nerve fiber layer (RNFL) thickness analysis performed twice using optical coherence...