Mary A. Ambach

ORCID: 0000-0003-2978-8594
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About
Contact & Profiles
Research Areas
  • Musculoskeletal pain and rehabilitation
  • Spine and Intervertebral Disc Pathology
  • Periodontal Regeneration and Treatments
  • Osteoarthritis Treatment and Mechanisms
  • Knee injuries and reconstruction techniques
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Shoulder Injury and Treatment
  • Tendon Structure and Treatment
  • Health and Medical Research Impacts
  • Pain Mechanisms and Treatments
  • Inflammasome and immune disorders
  • Mesenchymal stem cell research
  • Rheumatoid Arthritis Research and Therapies
  • Hematological disorders and diagnostics
  • Electrospun Nanofibers in Biomedical Applications
  • Wound Healing and Treatments
  • Musculoskeletal Disorders and Rehabilitation
  • Hip disorders and treatments
  • Extracellular vesicles in disease
  • Bone and Joint Diseases
  • Spondyloarthritis Studies and Treatments
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Innovations in Medical Education

Cardiovascular Medical Group
2021-2024

Healing Institute
2024

University of California, San Diego
2021

University of California, Los Angeles
2018

Orthopaedic Center
2016

Objective: This study aims at evaluating the clinical effects of Platelet Rich Plasma (PRP) and Hyaluronic Acid (HA) as individual treatments for mild to moderate Osteoarthritis (OA) it also examines potential synergistic PRP in combination with HA.Research continues emerge examining therapeutic efficacy HA autologous injectable joint arthritis.However, there is a paucity research investigating combining on pain functional status patients OA.Design: In this multi-center, randomized,...

10.46582/jsrm.1202011 article EN cc-by Journal of Stem Cells and Regenerative Medicine 2016-11-29

BACKGROUND: Chronic low back pain is one of the most common causes disability, affecting more than 600 million people worldwide with major social and economic costs. Current treatment options include conservative, surgical, minimally invasive interventional approaches. Novel therapeutic continue to develop, targeting biological cascades involved in degenerative processes prevent spinal surgical procedures. Both intradiscal platelet-rich plasma (PRP) bone marrow concentrate (BMC) applications...

10.36076/ppj.2024.27.e65 article EN Pain Physician 2024-01-20

Autologous platelet-rich plasma (PRP) preparations are prepared at point of care. Centrifugation cellular density separation sequesters a fresh unit blood into three main fractions: platelet-poor (PPP) fraction, stratum rich in platelets (platelet concentrate) and, bioformulation dependent, also leukocyte and erythrocyte fractions. The employment autologous platelet concentrates facilitates the biological potential to accelerate support numerous activities that can lead tissue repair,...

10.20944/preprints202405.1757.v1 preprint EN 2024-05-27

Knee osteoarthritis (KOA) is a prevalent condition characterized by the progressive deterioration of entire joint and has emerged as prominent contributor to disability on global scale. The nature disease its impact function significantly limit mobility daily activities, highlighting substantial influence patients' overall well-being. Stromal vascular fraction (SVF) heterogenous, autologous cell product, containing mesenchymal stem cells, derived from patient's subcutaneous adipose tissue...

10.1089/scd.2024.0008 article EN cc-by Stem Cells and Development 2024-02-22

Aim: To evaluate the use of a multitarget platelet-rich plasma (PRP) injection approach for treatment chronic low back pain (LBP). Materials & Methods: Forty-six patients with more than 12 weeks LBP who failed conservative treatments were injected PRP into facet joints, intervertebral discs, epidural space and/or paravertebral muscles. Visual analog scale and Roland-Morris Disability Questionnaire scores measured at baseline predefined intervals. Results: Mean visual was reduced from 8.48 to...

10.2217/rme-2021-0019 article EN Regenerative Medicine 2021-12-15
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