A5100436130- Spine and Intervertebral Disc Pathology
- Phytoestrogen effects and research
- GABA and Rice Research
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Musculoskeletal pain and rehabilitation
- Lymphoma Diagnosis and Treatment
- Parasitic infections in humans and animals
- Cervical and Thoracic Myelopathy
- Parasitic Infections and Diagnostics
- Spinal Cord Injury Research
- Breast Lesions and Carcinomas
- Alcohol Consumption and Health Effects
- Chronic Lymphocytic Leukemia Research
- Orthopaedic implants and arthroplasty
- Anesthesia and Pain Management
- Ophthalmology and Eye Disorders
- Cardiac Ischemia and Reperfusion
- Stroke Rehabilitation and Recovery
- Signaling Pathways in Disease
- Migraine and Headache Studies
- Hip and Femur Fractures
- Scoliosis diagnosis and treatment
- Multiple Sclerosis Research Studies
- Diet and metabolism studies
Tianjin Hospital
2025
82th Hospital of Pla
2023-2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Nanchang University
2023
Central South University
2022-2023
Second Xiangya Hospital of Central South University
2022-2023
First Affiliated Hospital of Nanchang University
2023
Henan Provincial People's Hospital
2023
Tsinghua University
2022
The complexity of the human intervertebral disc (IVD) has hindered elucidation microenvironment and mechanisms underlying IVD degeneration (IVDD). Here we determined landscapes nucleus pulposus (NP), annulus fibrosus (AF), immunocytes in by scRNA-seq. Six NP subclusters seven AF were identified, whose functional differences distribution during different stages (Pfirrmann I-V) investigated. We found MCAM+ progenitor AF, as well CD24+ MKI67+ NP, forming a lineage trajectory from CD24+/MKI67+...
Introduction The objective of this study is to construct a multi-epitope vaccine GILE containing B-cell and T-cell epitopes against Echinococcus Multilocularis ( E. multilocularis ) infection based on the dominant EMY162, LAP, GLUT1. Methods structure hydrophobicity were predicted by SWISSMODEL, pyMOL, SOPMA VMD, its sequence was optimized Optimum™ Codon. gene inserted into pCzn1 transformed Escherichia coli Arctic express competent cells. IPTG added induce expression recombinant proteins....
Purpose . The endplate defects (EDs), Modic changes (MCs), disc degeneration (DD), facet orientation (FO), and tropism (FT) were demonstrated to be related the low back pain (LBP). aim of this study was investigate possible correlations between them. Methods 75 patients reviewed evaluate degenerative change in vertebral bodies (EDs MCs), intervertebral discs joint (FO FT). All categorized into four groups based on grade EDs. Clinical outcomes evaluated with visual analog scale (VAS) Oswestry...
This study evaluated the effects of Lactiplantibacillus plantarum subsp. ZA3, Artemisia argyi and their combination, on fermentation characteristics, microbial community, mycotoxins crude flavonoids content fermented soybean meal during (under anaerobic conditions) aerobic exposure conditions). The results showed that ZA3+ groups had lower pH values higher lactic acid concentrations compared with controls, additives increased abundance decreased those Acetobacter Enterobacter; in particular,...
To observe the changes of lung injury when diabetic rats were treated with low concentration ethanol (EtOH) and analyze related mechanisms, male Sprague-Dawley (SD) divided into control, (DM), EtOH+DM groups. Diabetic rat was mimicked by injection streptozotocin intraperitoneally. Fasting blood glucose (FBG) level, weight (LW), body (BW), LW/BW measured. The tissue Type II alveolar cell detected. Pulmonary malondialdehyde (MDA) content superoxide dismutase (SOD) activity measured; meanwhile,...
Objective To investigate the relationship between degeneration of cervical intervertebral disc and paravertebral muscles[multifidus (MF), semispinalis (SCer), capitis (SCap) splenius (SPL)]. Methods 82 patients with chronic neck pain were randomly selected, including 43 males 39 females, 50.73 0.7.51 years old. All scanned by 3.0T MRI Philips Ingenia performed conventional sequence scanning fat measurement mDIXON-Quant cervical. Fat infiltration (FI) cross-sectional area (CSA) muscle (MF,...
Cosmetic filler injection can cause a variety of eye complications; however, there is currently no good way to evaluate injury severity and prognosis. By analyzing the manifestations severe ocular complications following cosmetic their prognosis, we propose new scale.Twenty-two eyes 22 patients experiencing were followed for 6 months observe characteristics, Best corrected visual acuity (BCVA), intraocular pressure (IOP), split lamp microscopy, fundus photography, optical coherence...
Alveolar echinococcosis (AE) is a parasitic disease caused by E. multilocularis metacestodes and it highly prevalent in the northern hemisphere. We have previously found that vaccination with Leucine aminopeptidase (EM-LAP) induced specific immune response had an inhibiting effect on parasites. In this study, therapeutic of recombinant EM-LAP (rEM-LAP) AE was evaluated verified using Ubenimex, broad-spectrum inhibitor LAP. The results reveal rEM-LAP could inhibit cyst growth invasion induce...
To determine the long-term radiological outcomes of PEEK rods in patients with lumbar degenerative diseases.Radiological cohort cases diseases following were retrospectively studied. Disc height index (DHI) and range motion (ROM) measured by x-rays. The CT scans reconstruction used to screw breakage, fracture, loosening intervertebral bony fusion status. MRI evaluate changes discs at non-fusion segments adjacent terms Pfirrmann Classification.A total 40 completed mean 74.8 ± 9.6 months...
Abstract Background Under the influences of chemotherapy regimens, clinical staging, immunologic expressions and other factors, survival rates patients with diffuse large B-cell lymphoma (DLBCL) are different. The accurate prediction mortality hazards is key to precision medicine, which can help clinicians make optimal therapeutic decisions extend times individual DLBCL. Thus, we have developed a predictive model predict hazard DLBCL within 2 years treatment. Methods We evaluated 406...
Background. The allergic lung inflammation is reduced in the diabetic rats which can be restored by treating it with insulin. As observed multiple studies, patients are more vulnerable to infections and their inflammatory reactions. There confirmations on insulin its effects control Objective. This study was performed understand correlation of impaired NF-kB activation sepsis-induced acute injury (ALI) rats. Material Methods. Streptozotocin used for induction diabetes sepsis induced colon...
Vacuum-assisted breast biopsy (VABB) has been routinely recommended for stereotactic intervention in cases of isolate mammographically-detected calcifications. Herein we aimed to evaluate and compare the diagnostic consistency accuracy calcified noncalcified specimens obtained from same sites sampling on mammography-visible In addition, presented procedure retrospectively evaluated usefulness VABB as well complications this technique over an eight-year experience our centre.This...
<title>Abstract</title> <bold>Objective</bold>: The purpose of this study is to determine the effect bone mineral density (BMD), as assessed by preoperative Dual-energy X-ray Absorptiometry (DEXA) scans and MRI-based vertebral quality (VBQ), on intraoperative total blood loss following transforaminal lumbar interbody fusion (TLIF). <bold>Methods</bold>: Patients who received TLIF for degenerative diseases at a single academic center from 2023-2024 were included in study. T-score VBQ score...