John R. Bumberry

ORCID: 0000-0003-2989-7221
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About
Contact & Profiles
Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • Breast Cancer Treatment Studies
  • MRI in cancer diagnosis
  • Global Cancer Incidence and Screening
  • Advanced MRI Techniques and Applications
  • Medical Imaging Techniques and Applications
  • BRCA gene mutations in cancer
  • Breast Implant and Reconstruction
  • Cancer Genomics and Diagnostics

Cooper Green Mercy Hospital
2024

Mercy Hospital Springfield
2017-2022

Background There are limited data from clinical trials describing preoperative MRI features and performance in the evaluation of mammographically detected ductal carcinoma situ (DCIS). Purpose To report qualitative DCIS, identification additional disease, associations imaging with pathologic, genomic, surgical outcomes Eastern Cooperative Oncology Group–American College Radiology Imaging Network (ECOG-ACRIN) E4112 trial. Materials Methods Secondary analyses a multicenter prospective trial...

10.1148/radiol.2021204743 article EN Radiology 2021-08-03

<h3>Importance</h3> Advanced diagnostics, such as magnetic resonance imaging (MRI) and gene expression profiles, are potentially useful to guide targeted treatment in patients with ductal carcinoma situ (DCIS). <h3>Objectives</h3> To examine the proportion of who converted mastectomy after MRI reasons for those conversions measure patient adherence radiotherapy guided by 12-gene DCIS score. <h3>Design, Setting, Participants</h3> Analysis a prospective, cohort, nonrandomized clinical trial...

10.1001/jamaoncol.2018.6269 article EN JAMA Oncology 2019-01-17

<h3>Importance</h3> Guiding treatment decisions for women with ductal carcinoma in situ (DCIS) requires understanding patient preferences and the influence of preoperative magnetic resonance imaging (MRI) surgeon recommendation. <h3>Objective</h3> To identify factors associated surgery preference receipt among a prospective cohort newly diagnosed DCIS. <h3>Design, Setting, Participants</h3> A study was conducted at 75 participating institutions, including community practices academic...

10.1001/jamanetworkopen.2022.10331 article EN cc-by-nc-nd JAMA Network Open 2022-05-10

Abstract BACKGROUND. Advanced diagnostics such as magnetic resonance imaging (MRI) and gene-expression profiles are potentially useful to guide treatment in patients with ductal carcinoma situ (DCIS). To evaluate these tests, we performed a prospective single arm multicenter study. We have previously reported the impact of MRI on surgical management DCIS patients, effect 12-gene Score (DS) radiotherapy (RT) use after wide local excision (WLE). now report pre-planned analysis ipsilateral...

10.1158/1538-7445.sabcs23-gs03-01 article EN Cancer Research 2024-05-02

534 Background: Prior retrospective studies have evaluated breast MRI in DCIS, and prospective-retrospective biomarker shown that the DCIS Score is prognostic for recurrence after BCS alone. E4112 a prospective cohort study designed to assess combined impact of on surgical RT management. Methods: Women diagnosed with screen-detected core biopsy, if eligible, underwent MRI. Those remaining so following related biopsies, no invasive disease, BCS. If final margins were ≥2 mm, lesion was...

10.1200/jco.2017.35.15_suppl.534 article EN Journal of Clinical Oncology 2017-05-20

6564 Background: Management of ductal carcinoma in situ (DCIS) remains variable, requiring an understanding patient preferences and concerns to enhance the treatment decision-making process. Pre-operative MRI surgeon recommendation can further inform surgery choice. Quality life (QoL) is also important consideration decision-making. The aims this study were assess patients’ before after consultation, concordance between preference received, trends health-related QoL (HRQL) among a...

10.1200/jco.2021.39.15_suppl.6564 article EN Journal of Clinical Oncology 2021-05-20
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