Federal regulations restrict methadone for opioid use disorder (OUD) treatment to licensed programs (OTPs). However, providers in other settings can administer withdrawal under the "72-hour rule" while linking further care. Prior work has demonstrated that initiation a low-barrier bridge clinic is associated with high OTP linkage and 1-month retention rates. We describe 2 novel applications of 72-hour rule which management facilitated inpatient hospitalization outpatient buprenorphine induction.

Objective: To describe the implementation of outpatient alcohol withdrawal management in a low-barrier substance use disorder (SUD) bridge clinic and short-term clinical outcomes. Methods: A Boston, MA implemented benzodiazepine tapers for patients at low risk seizures or delirium tremens. We conducted retrospective chart review who received one more doses between April 2021 January 2023. described patient characteristics evaluated rates taper completion, complications, medication (AUD)...

Methadone for opioid use disorder (OUD) treatment is restricted to licensed programs (OTPs) with substantial barriers entry. Underutilized regulations allow non-OTP providers administer methadone withdrawal up 72 h while arranging ongoing care. Our low-barrier bridge clinic implemented a new pathway treat and facilitate OTP linkage utilizing the "72-hour rule."Patients presenting hospital-based were evaluated OUD, withdrawal, goals. Eligible patients offered management rapid referral. OTPs...

Benzodiazepine-involved overdose deaths are rising, driven by increasing use of nonprescribed benzodiazepine pills. For patients who wish to stop use, rapid inpatient tapers typically the only option treat withdrawal. Substance disorder bridge clinics can provide high-touch care needed manage outpatient in at high risk due other substance disorders.

Introduction: Steroidal alkaloids are found in plants of the genus Veratrum. Their toxicity manifests as gastrointestinal symptoms followed by a Bezold–Jarisch reflex: hypopnea, hypotension, and bradycardia. Some Veratrum steroidal also teratogens interfering with hedgehog-2 signaling pathway, which causes cyclopsia holoprosencephaly. We present case accidental poisoning from parviflorum mistaken for edible Allium tricoccum (ramps, wild leek).Case history: A 27-year-old man his 25-year-old...

Objectives People who inject drugs (PWID) may experience high human immunodeficiency virus (HIV) risk and inadequate access to biomedical HIV prevention. Emerging data support integrating post-exposure pre-exposure prophylaxis (PEP, PrEP) into services already accessed by PWID. We describe PEP/PrEP eligibility receipt in a low-barrier substance use disorder bridge clinic located an area experiencing outbreak among PWID at the onset of COVID-19 pandemic. Methods Retrospective chart review new...

Abstract Background In the United States, methadone for opioid use disorder (OUD) is limited to highly regulated treatment programs (OTPs), rendering it inaccessible many patients. The “72-hour rule” allows non-OTP providers administer emergency withdrawal management while arranging ongoing care. Low-barrier substance (SUD) bridge clinics provide rapid access buprenorphine but offer an opportunity treat acute facilitating OTP linkage. We describe case of a patient with OUD who received in...

Abstract Background Addiction medicine providers have a key role in HIV prevention amidst rising incidence persons who inject drugs (PWID). Pre-exposure prophylaxis (PrEP) and post-exposure (PEP) are vastly underutilized this population. Inpatient hospitalization represents potential touchpoint for initiation of prophylaxis, though little research explores the addiction providers. Here we describe rates PrEP/PEP delivery to hospitalized PWID seen by an Consult Service (ACS) at urban,...

The development of eligibility criteria and use tranexamic acid in conjunction with a massive transfusion protocol (MTP) are described.The trauma surgery pharmacy departments collaborated to operationalize administration patients for whom an MTP was activated. at Boston Medical Center, urban, tertiary, academic medical center, is activated by the attending physician when patient expected require least 10 units packed red blood cells 24 hours. Tranexamic considered who arrived center within 8...

Purpose: To determine the cost-effectiveness of fulvestrant 250 mg compared to 500 in postmenopausal women with estrogen receptor-positive metastatic breast cancer and disease progression after antiestrogen therapy. Methods: A Markov model was constructed find incremental monthly when patients The duration 24 months. Clinical efficacy data inputs were derived from a phase III clinical trial demonstrating statistically significant increase progression-free survival receiving versus mg. Cost...

The position of the American College Medical Toxicology (ACMT) is as follows:The coronavirus disease 2019 (COVID-19) pandemic has created medication safety challenges affecting patients and staff.ACMT recommends modification some health care delivery practices to provide effective while responding drug shortages, infection risk, staffing changes.All must also consider staff preservation personal protective equipment (PPE).We encourage collaboration physicians clinical pharmacists at every...

Abstract Emergency medicine (EM) pharmacists provide high‐quality patient care in a fast‐paced environment by optimizing pharmacotherapy regimens and reducing medication errors. Current literature demonstrates higher rates of errors with antibiotics compared other classes. The aim this quality improvement (QI) project was to reduce 25% from baseline for antibiotic discharge prescriptions urinary tract infections (UTIs). This QI initiative utilized the Institute Healthcare Improvement Model...

Medication organizers increased compliance, but they do not contain child protective packaging. Medications have been involved in some pediatric exposures; however, previous reports describe if "one pill can kill" (1PCK) medications were the exposures. 1PCK may cause toxicity even with a single tablet.The purpose of this study is to type and presence dispensed medication at center.Adult patients who received blister packed from September 1, 2017 30, included retrospective review. excluded...

To address gender inequality, the American Society of Health-System Pharmacists (ASHP) created a steering committee that recommended collection baseline and ongoing metrics pharmacy leadership. The purpose this study was to quantify inequality in distributions residency program director (RPD) (DOP) positions investigate among recipients ASHP professional leadership awards.RPD DOP information for postgraduate year 1 (PGY1) programs included online directory were collected December 2020....

Background and Objectives: The aim of this quality improvement project was to decrease the percentage emergency department (ED) patients admitted with blood glucose (BG) level above 250 mg/dL less than 20%. Methods: A work group comprised physicians, pharmacists, endocrinologists collaborated standardize management ED hyperglycemia. Plan-Do-Study-Act cycles included education, monitoring BG 200 mg/dL, development an ED-specific insulin protocol. Results: Following initiative, 24.8% fewer...