- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Optical Coherence Tomography Applications
- Ocular Surface and Contact Lens
- Intraocular Surgery and Lenses
- Ophthalmology and Eye Disorders
- Cerebral Venous Sinus Thrombosis
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Ophthalmology and Visual Impairment Studies
- Neurological Disorders and Treatments
- Flavonoids in Medical Research
- Proteoglycans and glycosaminoglycans research
- Protease and Inhibitor Mechanisms
- Corneal Surgery and Treatments
- Retinal Development and Disorders
- Cell Adhesion Molecules Research
- Ocular and Laser Science Research
- Calpain Protease Function and Regulation
- Ocular Diseases and Behçet’s Syndrome
- Osteoarthritis Treatment and Mechanisms
- Ocular Disorders and Treatments
- Connexins and lens biology
University of Ulsan
2016-2025
Asan Medical Center
2016-2025
Ulsan College
2016-2025
National Research Foundation of Korea
2020
Ophthalmology Associates (United States)
2012-2014
IS Instruments (United Kingdom)
2011
Nune Eye Hospital
2011
University of Pittsburgh
1988-2009
Eye and Ear Foundation
2007
Visual Sciences (United States)
2007
To evaluate and compare the glaucoma discrimination ability of macular inner retinal layer (MIRL) thickness with that peripapillary nerve fiber (pRNFL) measured by spectral-domain optical coherence tomography (RTVue-100; Optovue Inc, Fremont, CA) in patients normal-tension (NTG).Sixty-five healthy subjects 102 NTG were enrolled. MIRL provided a ganglion cell complex (GCC) scan two RNFL thicknesses NHM4 (RNFL1) 3.45 (RNFL2) modes RTVue-100 system analyzed. The areas under receiver operating...
Purpose.: To investigate the relationship between clinical factors including 24-hour mean ocular perfusion pressure (MOPP, ⅔ × arterial [MAP] − intraocular [IOP]) and visual field (VF) progression in eyes with medically treated normal-tension glaucoma (NTG). Methods.: One hundred one of 101 NTG patients followed up for more than 4 years (mean follow-up, 6.2 ± 12.1 months) were included after retrospective chart review. Several demographic, systemic, risk factors, MOPP explored associations...
<h3>Background/aims:</h3> To investigate retinal nerve fibre layer (RNFL) thickness measurement reproducibility using conventional time-domain optical coherence tomography (TD-OCT) and spectral-domain OCT (SD-OCT), to evaluate two methods defining the optic head (ONH) centring: Centred Each Time (CET) vs Once (CO), in terms of RNFL variability on SD-OCT. <h3>Methods:</h3> Twenty-seven eyes (14 healthy subjects) had three circumpapillary scans with TD-OCT raster (three-dimensional or 3D image...
To evaluate the strength and pattern of relationship between visual field (VF) mean sensitivity (MS), assessed by standard automated perimetry (SAP), macular ganglion cell complex thickness (GCCT), measured with spectral-domain optical coherence tomography (SD-OCT).Ninety-seven glaucoma patients were enrolled. GCCT, determined (GCC) scanning, two peripapillary retinal nerve fiber layer (pRNFLT) measurements, using NHM4 (RNFL1) RNFL 3.45 (RNFL2) modes, recorded. MS was recorded on decibel...
Purpose.: We evaluated the clinical use of segmented macular layer thickness measurement in terms glaucoma diagnosis and ability to detect progression, compare such outcomes those by circumpapillary retinal nerve fiber (cRNFLT) total (TMT) measurements. Methods.: The study included 141 glaucomatous 61 healthy eyes. All eyes were subjected at least four spectral domain optical coherence tomography (SD-OCT) examinations (mean follow-up, 2.13 years). Segmented layers (NFL), ganglion cell inner...
To compare the glaucoma diagnostic capabilities of optic nerve head (ONH) parameters with retinal fiber layer thickness (RNFLT) using Cirrus spectral-domain optical coherence tomography (Carl Zeiss Meditec Inc, Dublin, CA; version 5.0.0.326).Two hundred twenty-nine glaucomatous patients, 405 preperimetric and 109 healthy individuals were imaged by disc cube mode. Correlations sought between RNFLT ONH (disc rim area, average vertical cup-to-disc ratio, cup volume). Areas under receiver...
The purpose of our study is to evaluate the effect age on various anterior segment (AS) parameters in healthy eyes using AS optical coherence tomography (OCT), and examine their relationship chamber angle (ACA) narrowing with age.A total 388 consecutive Korean subjects aged 30 89 years was imaged by OCT. Anterior depth (ACD), iris cross-sectional area (IA), thickness at 750 1500 μ from scleral spur (IT(750, 1500)), curvature (IC), lens vault (LV), (AA) were determined Image J software...
Purpose.: To evaluate the effect of myopia on progression primary open-angle glaucoma. Methods.: In this retrospective cohort study, eyes were classified into nonmyopic (NMG, >0 diopters [D]), mild to moderate (MMG, 0 −6 D), and highly myopic glaucoma (HMG, <−6 D) groups according level spherical equivalent. Glaucoma was determined either by optic disc/retinal nerve fiber layer (RNFL) photographs or serial visual field (VF) data. Cox's proportional hazard models used detect associations...
<h3>Background/aims</h3> This study aimed to investigate treatment patterns and medication adherence of glaucoma. It also identified key factors associated with non-adherence. <h3>Methods</h3> was a cross-sectional, observational study. Patients who use eye-drops for ≤2 years were recruited at 15 eye clinics from March November 2013. Data collected through self-administered questionnaires medical chart review. Medication evaluated using patients' self-report on pill count defined as...
Purpose: To evaluate the effect of age on global and sectoral vascular parameters peripapillary area macula in healthy eyes by using optical coherence tomography angiography (OCT-A). Methods: This retrospective cross-sectional study included 239 172 subjects. Subjects were scanned high-definition disc angio scan (4.5 × 4.5 mm), retina (6 6 optic nerve head/ganglion cell complex (GCC) modes OCT-A. Global circumpapillary vessel density (VD), parafoveal VD, retinal fiber layer (RNFL), GCC...
To investigate the characteristics of visual field (VF) progression in medically treated normal-tension glaucoma (NTG) patients (Koreans) with unstable ocular perfusion pressure (OPP).One hundred one eyes 101 NTG followed up for more than 4 years (mean follow-up, 6.2 ± 12.1 months) were included. Modified Anderson criteria (MC) and linear regression analysis (LA) VF mean deviation (MD) within central 10° to 24° area assessed determining groups lowest (LMF) highest (HMF) 24-hour OPP [MOPP =...
To investigate whether asymmetry in hemifield macular thickness can serve as an early indicator of glaucomatous structural damage using spectral domain optical coherence tomography.Five zones the map were defined. Each zone included reciprocal areas superior and inferior hemifield. Differences average retinal (DRT) between corresponding regional pairs measured each five 50 healthy eyes. An abnormality was defined DRT value lying outside 95% confidence intervals. eye considered to yield...
To evaluate whether intravitreal ranibizumab injection at cataract surgery prevents postoperative diabetic macular edema (PME) in patients with stable retinopathy without significant edema.Eighty cataract, retinopathy, and no were randomized to a sham group (cataract only) or undergoing plus intraoperative injection. Best-corrected visual acuities, central subfield thickness, total volume assessed baseline 1 week, 1, 3, 6 months postoperatively by spectral domain optical coherence...
To quantify long-term changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS optical coherence tomography (OCT) primary angle-closure suspect (PACS).Thirty-two PACS subjects were imaged at pre-LPI and 2 weeks 18 months post-LPI OCT. Anterior chamber depth (ACD), iris curvature (IC), thickness 750 1500 μm from the scleral spur (IT750, 1500), lens vault (LV), area (AA), (IA) estimated by ImageJ software (version 1.46). angle (ACA) (angle opening distance...
Purpose: To evaluate peripapillary microvascular changes in patients with primary open-angle glaucoma (POAG) after trabeculectomy using optical coherence tomography (OCT) angiography, and to determine the influence of lamina cribrosa (LC) displacement on microvasculature. Methods: The retinal microvasculature LC were imaged OCT angiography OCT-enhanced depth imaging, respectively. (LCD) measured before, 1 week, month, 3 months trabeculectomy. improvement was arbitrarily defined as a...