A5036042109- Gene Regulatory Network Analysis
- Computational Drug Discovery Methods
- Bioinformatics and Genomic Networks
- Microbial Metabolic Engineering and Bioproduction
- Alzheimer's disease research and treatments
- Protein Structure and Dynamics
- Sustainability and Ecological Systems Analysis
- RNA and protein synthesis mechanisms
- Mathematical and Theoretical Epidemiology and Ecology Models
- Misinformation and Its Impacts
- Electrochemical Analysis and Applications
- Metabolism, Diabetes, and Cancer
- Bayesian Modeling and Causal Inference
- Fungal Biology and Applications
- Antifungal resistance and susceptibility
- Complex Network Analysis Techniques
- COVID-19 epidemiological studies
- Metabolomics and Mass Spectrometry Studies
- Cognitive Science and Mapping
- Machine Learning in Bioinformatics
- Agriculture Sustainability and Environmental Impact
- Fungal Infections and Studies
- Influenza Virus Research Studies
- Plant and animal studies
- Cocoa and Sweet Potato Agronomy
De La Salle University
2016-2025
La Salle University
2019-2022
Malaviya National Institute of Technology Jaipur
2020
Jawaharlal Nehru Technological University, Kakinada
2020
University of the Philippines Manila
2020
University of the Philippines Diliman
2020
Max Planck Institute of Biochemistry
2019
Mariano Marcos State University
2019
University of the Philippines Los Baños
2019
Ludwig-Maximilians-Universität München
2019
Due to the outbreaks of Highly Pathogenic Avian Influenza A (HPAI) H5N6 in Philippines (particularly Pampanga and Nueva Ecija) August 2017, there has been an increase need cull domestic birds control spread infection. However, this method poses a negative impact on poultry industry. In addition, pathogenicity transmissibility both humans remain largely unknown which call for necessity develop more strategic methods virus. study, we constructed mathematical model bilinear half-saturated...
Two networks are said to be linearly conjugate if the solution of their dynamic equations can transformed into each other by a positive linear transformation. The study on dynamical equivalence in chemical kinetic systems was initiated Craciun and Pantea 2008 eventually led Johnston-Siegel Criterion for conjugacy (JSC). Several studies have applied Mixed Integer Linear Programming (MILP) approach generate conjugates MAK (mass action kinetic) systems, Bio-CRNs (which is subset Hill-type when...
This paper studies a chemical reaction network's (CRN) reactant subspace, i.e. the linear subspace generated by its complexes, to elucidate role in system's kinetic behaviour. We introduce concepts such as rank and deficiency compare them with their analogues currently used network theory. construct classification of CRNs based on type intersection between R stoichiometric S identify subnetwork S-complexes, complexes which, when viewed vectors, are contained S, tool study classes, which play...
We propose a process graph (P-graph) approach to develop ecosystem networks from knowledge of the properties component species. Originally developed as engineering tool for designing industrial plants, P-graph framework has key advantages over conventional ecological network analysis techniques based on input-output models. A is bipartite consisting two types nodes, which we represent components an ecosystem. Compartments within ecosystems (e.g., organism species) are represented by one...
Abstract Background Proteolytic breakdown of the amyloid precursor protein (APP) by secretases is a complex cellular process that results in formation neurotoxic Aβ peptides, causative neurodegeneration Alzheimer’s disease (AD). Processing involves monomeric and dimeric forms APP traffic through distinct compartments where various reside. Amyloidogenic processing also influenced modifiers such as sorting receptor-related (SORLA), an inhibitor major AD risk factor. Results In this study, we...
For a reaction network N with species set S , log-parametrized (LP) is non-empty of the form E(P, x * ) = {x ∈ R > | log -log P ⊥ } where (called LP set's flux subspace) subspace reference point) given element and parameter orthogonal complement .A kinetics K positive equilibria (PLP) system if its an set, i.e., E+(N K) E(PE, PE
This paper presents novel decomposition classes of chemical reaction networks (CRNs) derived from S-system kinetics. Based on the network theory initiated by Feinberg in 1987, we introduce concept incidence independent decompositions and develop $\mathscr{C}$- $\mathscr{C}^*$- which partition set complexes nonzero respectively, including their structure theorems terms linkage classes. Analogous to Feinberg's decomposition, demonstrate important relationship between sets complex balance...
Understanding how different diseases are related to one another based on their shared pathways could provide new insights into disease etiology and classification. The exploration of disease-disease associations by using a system-level biological data is made possible as the now publicly available via databases such in database maintained Kyoto Encyclopedia Genes Genomes (KEGG). By being able cluster visualize relationships with respect entities human diseases, researchers would be fully use...
Cacao farms worldwide lose up to 40% of their crops annually due several diseases. To reduce the damage, farmers and agricultural technicians regularly monitor well-being crops. But at present many still rely on visual inspection assess degree infection crops, resulting errors inconsistencies subjective nature assessment procedure. improve procedure, this research developed a framework for detecting segmenting infected parts fruit measure level cacao pods based k-means algorithm supplemented...
Pancreatic cancer is one of the most fatal types due to its difficulty being diagnosed in early stages. Presently, multiple screening procedures for this disease are required determine presence. In study, a pancreatic detection support tool implementing machine learning be created with vector machines (SVM) algorithm and mass spectrometry data patients controls as training testing datasets. The final output would aid researchers detecting (complementing current common procedures), finding...