- Cellular Mechanics and Interactions
- Electrospun Nanofibers in Biomedical Applications
- Muscle Physiology and Disorders
- Malaria Research and Control
- 3D Printing in Biomedical Research
- Hippo pathway signaling and YAP/TAZ
- Clostridium difficile and Clostridium perfringens research
- Hemoglobinopathies and Related Disorders
- Gout, Hyperuricemia, Uric Acid
- Dietary Effects on Health
- Gut microbiota and health
- Complement system in diseases
- Liver Disease and Transplantation
Indiana University – Purdue University Indianapolis
2023-2025
Indiana University School of Medicine
2023-2025
University of Colorado Boulder
2019-2021
Skeletal muscle stiffening after injury induces proliferation and activation of stem cells via YAP TAZ signaling.
There is a growing interest in materials that can dynamically change their properties the presence of cells to study mechanobiology. Herein, we exploit 365 nm light mediated [4+4] photodimerization anthracene groups develop cytocompatible PEG-based hydrogels with tailorable initial moduli be further stiffened. A hydrogel formulation stiffen from 10 50 kPa, corresponding stiffness healthy and fibrotic heart, respectively, was prepared. This system used monitor stiffness-dependent localization...
Abstract Acute kidney injury (AKI) is common and predicts mortality in severe malaria. Studies have reported an increased incidence of AKI males with hemolytic features SM. G6PD deficiency, X-linked enzymopathy, can induce hemolysis. We evaluated whether the African allele (A-) was associated children The prevalence deficiency 16.7% among hemizygous 2.4% females. 2.56-fold odds (95% CI, 1.33 to 4.93, p=0.005), adjusting for age, sex, site, nutritional status,
Abstract There is a growing interest in materials that can dynamically change their properties the presence of cells to study mechanobiology. Herein, we exploit 365 nm light mediated [4+4] photodimerization anthracene groups develop cytocompatible PEG‐based hydrogels with tailorable initial moduli be further stiffened. A hydrogel formulation stiffen from 10 50 kPa, corresponding stiffness healthy and fibrotic heart, respectively, was prepared. This system used monitor stiffness‐dependent...
There is increasing evidence that microbes residing within the intestines (gut microbiota) play important roles in well-being of humans. Yet, there are considerable challenges determining specific role gut microbiota human diseases owing to complexity diverse internal and environmental factors can contribute diseases. Mice devoid all microorganisms (germ-free mice) be colonized with stool samples examine contribution a disease. These approaches have been primarily focused on obtained from...