A5101960320- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Immune Cell Function and Interaction
- Aquaculture Nutrition and Growth
- Immunotherapy and Immune Responses
- Galectins and Cancer Biology
- Cancer-related Molecular Pathways
- scientometrics and bibliometrics research
- Silkworms and Sericulture Research
- interferon and immune responses
- Cancer therapeutics and mechanisms
- Wnt/β-catenin signaling in development and cancer
- Cancer Mechanisms and Therapy
- Clostridium difficile and Clostridium perfringens research
- Lung Cancer Research Studies
- Microscopic Colitis
- Plant Gene Expression Analysis
- Cancer Immunotherapy and Biomarkers
- Inflammatory Biomarkers in Disease Prognosis
- Aquatic life and conservation
- Genetic diversity and population structure
- Photosynthetic Processes and Mechanisms
- Gastric Cancer Management and Outcomes
Shantou University
2024
Shantou University Medical College
2024
Beibu Gulf University
2020-2024
Nanchang Institute of Technology
2021-2023
Northwest A&F University
2022
Zhejiang University
2019-2022
Hangzhou First People's Hospital
2013-2022
Hangzhou Cancer Hospital
2020
Southwest University
2014
State Key Laboratory of Silkworm Genomic Biology
2014
Gene flow plays an important role in domestication history of domesticated species. However, little is known about the demographic silkworm involving gene with its wild relative.In this study, four model-based evolutionary scenarios to describe B. mori were hypothesized. Using Approximate Bayesian Computation method and DNA sequence data from 29 nuclear loci, we found that at bottleneck model most likely scenario for domestication. The starting time was estimated be approximate 7,500 years...
Due to the short freshness period of vegetables, ensure commodities should be stocked in superstores facilitate replenishment pricing. so a reasonable strategy is crucial more effectively help around world manage inventory, improve sales efficiency, optimize business management and maximize revenue. Based on this, this paper determines future as well pricing strategies using pricing, wastage, vegetables superstore for last three years Goods Sample This data based time series study. Wavelet...
The primary purpose of this study was to investigate the correlation between single nucleotide polymorphisms (SNPs) ATP binding cassette superfamily G member 2 (ABCG2) and outcome tyrosine kinase inhibitions (TKIs) therapy in Chinese advanced non-small-cell lung cancer (NSCLC) patients. secondary objective identify biomarkers evaluate response treatment targeted therapy.SNP genotyping (34 G/A, 421 C/A, 1143 C/T -15622 C/T) ABCG2 gene 100 patients performed using matrix-assisted laser...
Gefitinib has come to be the most widely used epidermal growth factor receptor-tyrosine kinase inhibitor in treatment of advanced non-small cell lung cancer (NSCLC) Asian patients. Common side effects include mild moderate skin rash and diarrhea, however, drug-induced liver injury varying severity is overlooked long-term gefitinib administration rarely reported. The current case report presents a female Chinese NSCLC patient who developed severe gefitinib-induced hepatotoxicity was...
Serine-arginine protein kinase (SRPK) belongs to a class of cell cycle regulating kinases that can phosphorylate proteins containing serine/arginine-Rich (SR) regions. SR are family RNA binding phosphoproteins control both constitutive and alternative pre-mRNA splicing events. However, little is known about their role in non-small lung cancer (NSCLC). In the present study, we found serine-arginine 2 (SRPK2) expression was upregulated NSCLC tissues compared with adjacent normal tissues....
Crizotinib is an oral small-molecule inhibitor of anaplastic lymphoma kinase (ALK) tyrosine‑kinase that has been approved for treating patients with advanced echinoderm microtubule associated protein like 4‑ALK rearranged non‑small‑cell lung cancer (NSCLC). Toxic epidermal necrolysis (TEN) a rare adverse event crizotinib. The present study reported case 75‑year‑old Chinese male patient NSCLC ALK fusion, who developed TEN after 56 days crizotinib treatment and demised due to this...
Immune checkpoint inhibitors (ICIs) therapy has revolutionized the treatment patterns of non-small cell lung cancer (NSCLC). However, patients treated with ICIs may experience immune-related adverse events (irAEs). Markers that could predict onset irAEs are still unclear. Here, we report possible correlation baseline peripheral lymphocytes and clinical outcomes in advanced NSCLC receiving ICIs. A total 109 from April 2017 to January 2021 were analyzed retrospectively. Logistic Cox regression...
Classical cadherin gene family relies on calcium ions in playing an important role adhesion between cells. However, comprehensive studies to identify classical families Nile tilapia (Oreochromis niloticus) have not been conducted. In this study, 18 members were screened from using various bioinformatics methods. These cadherins randomly scattered across eight different linkage groups and shared a conserved LDRE motif. A phylogenetic tree was constructed explore the evolution of members. The...
Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI
To confirm a new allele HLA-B*13:01:06 and analyze its nucleotide sequence.Genomic DNA was extracted using Qiagen extraction kit. Nucleotide sequences of HLA-A, HLA-B, HLA-C HLA-DRB1 were analyzed by polymerase chain reaction-sequence based typing (PCR-SBT). HLA high-resolution results assigned, the HLA-B locus compared with that HLA-B*13:01:01.The sequence shows strong similarity to HLA-B*13:01:01. One in exon 2 has changed from G A at position 219 (codon 49 GCG>GCA), which however did not...
Manganese superoxide dismutase (MnSOD) and catalase (CAT) could eliminate reactive oxygen species (ROS) maintain the reduction-oxidation balance in cells. This study aimed to investigate their functions turbot (Scophthalmus maximus) response Vibro anguillarum challenge. SmMnSOD, full-length liver cDNA of MnSOD from S. maximus , was cloned by fast amplification ends (RACE). Sequencing nucleotides indicated that SmMnSOD 1267 base pairs with a 684-base-pair open reading frame, encoding 228...
Gastric cancer has high mortality rates worldwide. Therefore, there is a need to identify prognostic biomarkers. This study evaluated the association between GFRA2 expression levels with clinicopathological features and prognosis in gastric using data extracted from The Cancer Genome Atlas (TCGA) database series of algorithms. Survival analysis was performed Kaplan-Meier method. Univariate multivariate Cox regression analyses were used analyze different clinical survival. Single-sample gene...
To analyze the full nucleotide sequence of a null allele major histocompatibility complex class I chain-related gene (MICA).A sequence-based typing method was used to determine MICA gene. Potential alleles were identified with computer program.The has possessed similar that MICA*027 except for C→T substitution at position 184 in codon 62 (CAG→TAG) exon 2. As stop codon, this may result truncated protein.A been identified. The submitted Genbank database (submission No. HWS10011131), which...