A5025665749- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Anorectal Disease Treatments and Outcomes
- Sexual function and dysfunction studies
- Urinary and Genital Oncology Studies
- Pelvic and Acetabular Injuries
- Urologic and reproductive health conditions
- Prostate Cancer Treatment and Research
- Genital Health and Disease
- Cancer Immunotherapy and Biomarkers
- Hormonal and reproductive studies
- Hernia repair and management
- Renal cell carcinoma treatment
- Sexuality, Behavior, and Technology
- Sexual Differentiation and Disorders
- Ureteral procedures and complications
- Ovarian cancer diagnosis and treatment
- Surgical Sutures and Adhesives
- Cardiovascular Disease and Adiposity
- Esophageal and GI Pathology
- Cancer, Lipids, and Metabolism
University of Foggia
2014-2024
Ospedali Riuniti di Foggia
2019-2023
University of Bari Aldo Moro
2005-2014
Pentraxin-3 (PTX3) belongs to the pentraxine family, innate immune regulators involved in angiogenesis, proliferation and escape cancer.Here, we evaluated PTX3 tissue expression serum levels as biomarkers of clear cell renal carcinoma (ccRCC) analyzed possible role complement system activation on tumor site.A 10-year retrospective cohort study including patients undergoing nephrectomy for ccRCC was also performed.PTX3 elevated both neoplastic lines tissues, while it absent normal proximal...
Background: Bladder cancer (BCa) is a heterogeneous disease with variable prognosis and natural history. Cardiovascular (CVD), although completely different, has several similarities possible interactions cancer. The association between them still unknown, but common risk factors the two suggest shared biology. Materials Methods: This was retrospective study that included patients who underwent transurethral resection of bladder tumor at high-volume institutions. Depending on presence...
The association between PSA density, prostate cancer (PCa) and BPH is well established. aim of the present study was to establish whether density can be used as a reliable parameter predict csPCa determine its optimal cutoff exclude increased levels due intraprostatic inflammation. This large prospective single-center, observational evaluating role in discrimination inflammation clinically significant PCa (csPCa). Patients with ≥ 4 ng/ml and/or positive digito-rectal examination (DRE)...
Abstract Introduction Overactive bladder (OAB) and underactive (UAB) could be associated with metabolic syndrome, affective disorders, sex hormone deficiency, changes in urinary microbiota, functional gastrointestinal or autonomic nervous system dysfunction. Objectives The aim of this Think Tank was to provide a guide on how investigate OAB and/or detrusor underactivity (DU) patients better clarify the underlying pathophysiology possibly personalize treatment. Methods A compendium discussion...
Dendritic cells (DCs) are potent antigen presenting and represent attractive candidates for use in novel immunotherapies patients with renal cell carcinoma (RCC), a disease that has proven refractory to conventional treatment modalities, such as chemotherapy radiotherapy. Given the perceived need augment antitumor type-1 immunity (TC1 Th1) therapeutic end point, known functional plasticity of DC populations may display heterogeneous capacity promote T-cell responses, we sought identify...
The present study aimed to determine the ability of novel nomograms based onto readily-available clinical parameters, like those related benign prostatic obstruction (BPO), in predicting outcome first prostate biopsy (PBx). To do so, we analyzed our Internal Review Board-approved prospectively-maintained PBx database. Patients with PSA>20 ng/ml were excluded because their high risk harboring cancer (PCa). A total 2577 found be eligible for analyses. age, PSA, digital rectal examination...
Intravesical immunotherapy with bacillus Calmette-Guerin (BCG) is the standard therapy for high-risk non-muscle invasive bladder cancer (NMIBC). The superiority of any BCG strain over another could not be demonstrated yet.Patients NMIBCs underwent adjuvant induction ± maintenance schedule intravesical either TICE or RIVM at two high-volume tertiary institutions. Only BCG-naïve patients and those treated same course follow-up were included. One-to-one (1:1) propensity score matching (PSM)...
The purpose of this study was to investigate the relationship between bladder outlet obstruction (BOO) and risk being diagnosed with prostate cancer (PCa). Study population consisted 2673 patients scheduled for first biopsy (PBx). All underwent uroflowmetry before PBx; those a peak flow rate (PFR) <10 mL/s were considered have BOO. incidence PCa 41.3% (1104/2673) in overall 34.1% (659/1905) serum prostate-specific antigen (PSA) ≤ 10 ng/mL. Univariate multivariate logistic regression analyses...
Background: the aim of this study was to perform an Italian telematics survey analysis on changes in couples’ sex lives during coronavirus disease 2019 (COVID-19) lockdown. Methods: a multicenter cross sectional conducted people sexually active and stable relationships for at least 6 months. To evaluate male female sexual dysfunctions, we used international index erectile function (IIEF-15) (FSFI), respectively; marital quality stability were evaluated by adjustment test (items 10–15);...
Abstract Introduction Overactive bladder (OAB) and Underactive (UAB) could be associated with metabolic syndrome, affective disorders, sex hormone deficiency, changes in urinary microbiota, functional gastrointestinal or autonomic nervous system dysfunction. Objectives The aim of this Think Tank was to provide a guide on how investigate OAB and/or detrusor underactivity (DU) patients better clarify the underlying pathophysiology possibly personalize treatment. Methods A compendium discussion...
Previous published studies have shown an improvement of penile hemodynamic parameters after low-intensity extracorporeal shockwave therapy (Li-ESWT). However, the clinical significance these findings remains unclear, and definitive selection criteria for Li-ESWT based on preexisting comorbidities yet to be established. This was observational study 113 patients with ED, evaluated between January 2019 December 2021 in Andrology Unit at Department Urology Renal Transplantation, University...
The autologous rectus fascia pubovaginal sling has been a safe and effective means of correcting stress urinary incontinence. We tested the feasibility using larger graft to correct cystocele with or without incontinence.Between January 2006 October 2010, 30 patients symptomatic underwent procedure, including 14 16 concomitant technique is modification standard procedure. A large trapezoidal (major base 6 cm, minor 4 cm height 5 cm) used instead 2 sutures suspend corners. at level mid...