A5062283874- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Breast Cancer Treatment Studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- T-cell and Retrovirus Studies
- Breast Implant and Reconstruction
- Hematopoietic Stem Cell Transplantation
- Breast Lesions and Carcinomas
- Platelet Disorders and Treatments
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Neutropenia and Cancer Infections
- Complement system in diseases
- Hematological disorders and diagnostics
- Renal Diseases and Glomerulopathies
- Spinal Hematomas and Complications
- Eosinophilic Disorders and Syndromes
- Liver Disease Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Lipid metabolism and disorders
- Glycosylation and Glycoproteins Research
- Melanoma and MAPK Pathways
- Liver physiology and pathology
- Management of metastatic bone disease
- Protein Degradation and Inhibitors
Moffitt Cancer Center
2013-2024
University of South Florida
2009-2023
Florida College
2009-2011
University of Central Florida
2007
e15753 Background: Microsatellite instability (MSI) is a feature of cancers related to defective mismatch repair protein functions and has been well characterized in colorectal cancer (CRC). In CRC, high levels MSI have found predict better overall prognosis increased benefit immune based therapies. Pancreatic few systemic treatment options available highly resistant chemotherapy radiation. Immune therapies had great success many cancers, however they shown little clinical pancreatic cancer....
Abstract Learning Objectives After completing this course, the reader will be able to: Identify patients likely to benefit from preoperative axillary ultrasound.Define clinical implications of a ultrasound and FNA in patient care. CME This article is available for continuing medical education credit at CME.TheOncologist.com Purpose. Preoperative sonography with fine needle aspiration (FNA) invasive breast cancer identifies nodal metastasis who can spared further surgery. Indiscriminate use...
Abstract Current management of locoregional and oligometastatic melanoma is typically with surgery; however, some patients are unable to undergo resection due location/size their tumors and/or the anticipated morbidity surgery. While there currently no established guidelines for neoadjuvant therapy in melanoma, BRAF‐targeted may make more feasible. A retrospective analysis was conducted 23 BRAFV600‐mutant, stage III/IV treated prior surgery, adjuvant treatment. Surgical specimens,...
Pancytopenia and neutropenia due to coronavirus disease 2019 (COVID-19) are rare. Here we report a case of as sequela COVID-19 with concern for bone marrow infiltration. The patient was successfully treated granulocyte colony-stimulating factor.
Caplacizumab prevents platelet adhesion and has been approved for acquired thrombotic thrombocytopenic purpura (aTTP). This study was retrospective, including all patients diagnosed with aTTP treated caplacizumab since commercial availability in 2019 until 28 February 2021 at a single academic hospital no exclusion criteria. Results used definitions outcomes from the International Working Group Consensus. Ten received caplacizumab. The median age 52 years. Six (60%) had refractory while 4...
Abstract Introduction: Autoimmune hypophysitis (AH) is an immune-related adverse effect (ir-AE) of the human IgG1 monoclonal antibody ipilimumab. Evidence suggests AH mediated by complement deposition in adenohypophyseal cells expressing cytotoxic T lymphocyte antigen-4 (CTLA-4). Despite increasing incidence, remains poorly characterized. We conducted a retrospective cohort study melanoma subjects treated with ipilimumab, primary objective to characterize and examine its association overall...
Abstract Background Complement‐mediated thrombotic microangiopathy (CM‐TMA), also called atypical hemolytic uremic syndrome (aHUS), is a difficult‐to‐diagnose rare disease that carries severe morbidity and mortality. Anti‐C5 monoclonal antibodies (aC5‐mab) are standard treatments, but large studies long‐term data scarce. Here, we report our single institution experience to augment the knowledge of CM‐TMA treated with aC5‐mab therapy. Methods We aimed assess short effects in patients...
Eosinophilic esophagitis is an under-recognized inflammatory disorder of the esophagus. It has been frequently diagnosed in pediatric patients; however, over last few years, there increase number cases recognized adults as well. Despite this fact, eosinophilic (EE) often a delayed diagnosis primary care setting due to overlapping symptoms it shares with other esophageal and gastrointestinal disorders such gastroesophageal reflux disease gastroenteritis, well lack awareness among physicians...