A5084888655- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Fermentation and Sensory Analysis
- Probiotics and Fermented Foods
- Mast cells and histamine
- Immune Cell Function and Interaction
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Animal Disease Management and Epidemiology
- IL-33, ST2, and ILC Pathways
- Adipokines, Inflammation, and Metabolic Diseases
- Gut microbiota and health
- Escherichia coli research studies
- Microbial Metabolism and Applications
- Plant and Fungal Interactions Research
- Immune cells in cancer
- Dermatology and Skin Diseases
- Cholesterol and Lipid Metabolism
- Invertebrate Immune Response Mechanisms
- Transgenic Plants and Applications
- Cancer-related molecular mechanisms research
- Metabolomics and Mass Spectrometry Studies
- Biochemical and biochemical processes
- Exercise and Physiological Responses
China Agricultural University
2020-2023
Ministry of Education of the People's Republic of China
2021
The increase in high-fat diet (HFD)-induced obesity and food allergy leads to an assumption that the 2 are related. This study aims (1) systematic verification of HFD-induced aggravates (2) explore correlation molecular mechanisms promotes allergy.Female BALB/c mice divided into control group (control), ovalbumin (OVA)-sensitized (OVA), (HFD), allergic (HFD + OVA).In vivo data showed HFD feed enhance clinical symptoms intestinal mucosa villi shed on mice. Moreover, we found OVA irritation...
Baijiu, one of the world’s oldest distilled liquors, is widely consumed globally and has gained increasing popularity in East Asia. However, a comprehensive understanding underlying principles behind this traditional liquor product remains elusive. Currently, Baijiu facing industrial challenge modernization standardization, particularly terms food quality, safety, sustainability. The current study selected Lactobacillus brevis strain based on experiments conducted to assess its environmental...
Scope Oral food challenges (OFCs) are currently the gold standard for determining clinical reactivity of allergy (FA) but time‐consuming, expensive, and risky. To screen novel peripheral biomarkers FA characterize aberrant lipid metabolism in serum, 24 rats divided into four groups: peanut, milk, shrimp (PA, MA, SA, respectively) control groups, with six each group, used widely targeted lipidomics transcriptomics analysis. Methods results Widely reveal 144, 162, 206 differentially...
Shrimp allergy (SA) is pathological type 2 inflammatory immune responses against harmless shrimp protein allergen, which caused by complex interactions between dendritic cells (DCs) and other cells. Lipid metabolism in different DCs states are significantly changed. However, the lipid of spleen SA remain ambiguous. In this study, we established a BALB/c mouse extract-induced model to determine profile SA, molecular mechanism inflammation was preliminarily studied. Spleen were sorted...
There is no universally accepted uniform research to classify the severity of allergic reactions triggered by different food allergens. We established a allergy model based on repeated intragastric administrations proteins from peanut, egg, milk, or soybean mixed with cholera toxin followed oral challenges high dose sensitizing proteins. Increased specific IgE, IgG1, symptom scores, histamine, murine mast cell proteases-1, vascular leakage, Th2 cytokines, and infiltration in lungs intestine...
Peanut allergy (PA) has become a clinical and public health problem, which is mainly regulated by genetics, immune responses, environmental factors. Diagnosis treatment for PA have always remained huge challenges due to its multiple triggers. Studies shown that long non-coding RNAs (lncRNAs) play critical role in the development of allergic diseases.In current study, we examined plasma lncRNA expression profiles peanut Brown Norway rats healthy controls 496 differently expressed lncRNAs were...