A5110853298- Inflammatory Bowel Disease
- Microscopic Colitis
- COVID-19 Clinical Research Studies
- Eosinophilic Esophagitis
- Gastric Cancer Management and Outcomes
- Diverticular Disease and Complications
- Consumer Behavior in Brand Consumption and Identification
- Colorectal Cancer Surgical Treatments
- Intensive Care Unit Cognitive Disorders
- Helicobacter pylori-related gastroenterology studies
- Diagnosis and treatment of tuberculosis
- Thermal Regulation in Medicine
- Kawasaki Disease and Coronary Complications
- Celiac Disease Research and Management
- Neuroendocrine Tumor Research Advances
- Chronic Lymphocytic Leukemia Research
- Immunodeficiency and Autoimmune Disorders
- Biosimilars and Bioanalytical Methods
- Autoimmune and Inflammatory Disorders
- Coronary Artery Anomalies
- Cytokine Signaling Pathways and Interactions
- Long-Term Effects of COVID-19
- Smoking Behavior and Cessation
- Digital Marketing and Social Media
- Mechanical Circulatory Support Devices
Torbay Hospital
2022-2024
Torbay and South Devon NHS Foundation Trust
2018-2024
Manchester University NHS Foundation Trust
2024
University of Oxford
2019-2022
Oxford Health NHS Foundation Trust
2022
Boston Children's Health Physicians
2020
Oxford BioMedica (United Kingdom)
2019
Oxford University Hospitals NHS Trust
2016
Hospital Clínic de Barcelona
2009
Influencer marketing is a strategy that businesses use to promote their products or services through partnerships with popular individuals entities, known as influencers, on various social media platforms. This study embarks bibliometric analysis of influencer marketing, utilizing the Scopus and Web Science (WoS) databases collect comprehensive bibliographic data. Employing PRISMA Flow diagram methodology, this research meticulously identifies, screens, includes pertinent papers in analysis,...
A defunctioning stoma is a therapeutic option for colonic or perianal Crohn's disease. In the pre-biologic era response rate to in our unit was high (86%), but intestinal continuity only restored 11-20%. Few data exist on outcome of since widespread introduction biologicals.All patients undergoing colonic/perianal disease 2003-2011 were identified from prospective database. Indications surgery, medical therapy, and long-term clinical recorded. Successful restoration defined as no at last...
Abstract Aim Temporary faecal diversion after ileocolic resection (ICR) for Crohn’s disease reduces postoperative anastomotic complications in high‐risk patients. The aim of this study was to assess if approach also long‐term surgical recurrence. Method This a multicentre retrospective review prospectively maintained databases. Patient demographics, medical and details were collected by three specialist centres. All patients had undergone an ICR between 2000 2012. primary end‐point Results...
Abstract Background Upadacitinib, a selective Janus Kinase inhibitor, is the newest advanced therapy in our armamentarium for treatment of Crohn’s Disease (CD). It has been licensed use moderate-to-severely active CD. However, we have limited evidence its effectiveness ‘real-world’ setting. Methods We undertook retrospective cohort study on CD patients treated with upadacitinib 24 UK hospitals. Clinical endpoints were reviewed at 12 weeks compared to baseline. remission was defined as...
Abstract Background Tofacitinib, filgotinib, and upadacitinib are Janus Kinase inhibitors (JAKi) effective in inducing maintaining remission moderate-to-severe ulcerative colitis (UC). Limited data exists regarding outcomes patients on a second JAKi after prior treatment failure. Here we describe the effectiveness of induction with cohort UC patients. Methods In this retrospective study, from 20 UK hospitals treated were included. Clinical endpoints, as defined Table 1, assessed at week 8....
CD, 2 for UC and one indeterminate colitis. The mean age at diagnosis of HLH was 35 years (range 19 61). Twenty five patients were under thiopurines in monotherapy (n = 17), combination with steroids 3), anti-TNF 4) or both 1); patient received on steroids, tacrolimus mycophenolate mophetil. At the time diagnosis, immunosuppressive drugs discontinued all patients. clinical features were: fever (39 40oC) (27/27), rash (9/27), lymphadenopathy (11/27), splenomegaly (11/26), dyspnea (8/27),...
Abstract Background Vedolizumab, a gut-selective monoclonal antibody targeting α4β7-integrin, was recently licenced as subcutaneous (SC) preparation after demonstrating efficacy compared to placebo at maintaining remission in IBD patients who had clinical response intravenous (IV) induction therapy. We aimed assess real-world experience of switching SC administration. Methods Patients across 10 UK centres completed with IV vedolizumab were offered Demographic data and baseline disease...
Presentationsrecurrence.Statistical analysis: Kaplan Meier survival method, Chi-square, Student t-test.Results: The two groups were comparable as gender, age at surgery, smoking habits, pattern of CD (perforating / not perforating), and disease duration before surgery.One year after a small, even if statistically significant, risk reduction clinical recurrence was observed in mesalamine treated group ( 7.6%; 95% CI 18.0% to 2.8%).Within 10 years the cumulative probability surgical similar...
s of the 4th Congress ECCO European Crohn’s and Colitis Organisation S91 (year 1 5) to 83.0% 11 15). There was no relation these data age, gender, disease extension, medication. Conclusion: UC activity reduced during long time course independent other investigated parameters. P204 IBD care in Europe: a comparative audit ulcerative colitis between Oxford Milan using validated National UK Audit Tool A. Cassinotti1 *, S. Keshav2, Ardizzone1, N. Mortensen2, G. Sampietro1, P. Fociani1, B.F....
Steroid-free remission is an important goal of IBD therapy. Improved access to effective therapies and changes in physician awareness excess steroid exposure might impact this goal. The aim study was evaluate temporal prescribing UK outpatients the context major guidelines participation audit tailored service changes. Steroid use over previous 12 months recorded for unselected outpatient attenders against a definition from ECCO guidelines. Data were collected seven centres that had completed...
Abstract Background The L!RIC trial confirmed that surgical treatment of limited ileocaecal Crohn’s disease (ICCD) has comparable outcomes to antiTNF therapy. However, strict exclusion criteria for a randomised controlled make it difficult determine if results can be generalised wider population. We therefore compared clinical between resection or other biologic therapy amongst biologic-naïve patients with provide real world experience. Methods All ICCD who were naïve both and surgery,...