- Cardiac Imaging and Diagnostics
- Jewish and Middle Eastern Studies
- Global Peace and Security Dynamics
- Advanced MRI Techniques and Applications
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Advanced X-ray and CT Imaging
- Middle East Politics and Society
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Cardiac tumors and thrombi
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Structural Anomalies and Repair
- Middle East and Rwanda Conflicts
- COVID-19 and healthcare impacts
- Vascular Tumors and Angiosarcomas
- Diet and metabolism studies
- Pericarditis and Cardiac Tamponade
- Blood Pressure and Hypertension Studies
- Nutritional Studies and Diet
- Metallurgy and Cultural Artifacts
- Cardiac Arrest and Resuscitation
Soroka Medical Center
2012-2025
Ben-Gurion University of the Negev
2008-2023
University Medical Center
2020
University Hospital and Clinics
2020
Cedars-Sinai Medical Center
2011-2019
Cedars-Sinai Smidt Heart Institute
2019
Wockhardt (United States)
2018
Cornell University
2016
Barzilai Medical Center
2012
Hebrew University of Jerusalem
2005
Objective To examine the effectiveness of green-Mediterranean (MED) diet, further restricted in red/processed meat, and enriched with green plants polyphenols on non-alcoholic fatty liver disease (NAFLD), reflected by intrahepatic fat (IHF) loss. Design For DIRECT-PLUS 18-month randomized clinical trial, we assigned 294 participants abdominal obesity/dyslipidaemia into healthy dietary guidelines (HDG), MED green-MED weight-loss diet groups, all accompanied physical activity. Both isocaloric...
High levels of circulating cell free DNA (CFD) have been associated with poor prognosis in various diseases. Data pertaining to CFD acute myocardial infarction (MI) are scarce. The available data obtained by either electrophoresis or polymerase chain reaction. We evaluated a novel method for the detection patients ST elevation (STEMI) and examined its correlation established markers necrosis ventricular function.Serum concentrations CFD, troponin-T creatine kinase (CK) were measured...
Hybrid PET myocardial perfusion imaging (MPI) with CT allows the incorporation of coronary artery calcium (CAC) into clinical protocol. We aimed to determine whether combined analysis MPI and CAC could improve diagnostic accuracy in detection obstructive disease (CAD).Consecutive patients (n = 152; mean age ± SD, 69 12 y) without prior CAD, referred (82)Rb followed by invasive angiography performed within 14 days, were studied. Myocardial was quantified automatically for left anterior...
Abstract Background ST-Elevation Myocardial Infarction (STEMI) is a critical condition, especially in the older population, who are at increased risk due to comorbidities and delayed diagnosis. This study aimed investigate impact of ethnicity on clinical characteristics, treatment timelines, outcomes patients with STEMI southern Israel, comparing Jewish Bedouin populations. Methods We conducted retrospective cohort Soroka University Medical Center from 2016 2022, including (≥ 65 years)...
Circulating miRNAs are increasingly being considered as biomarkers in various medical contexts, but the value of analyzing isomiRs (isoforms canonical miRNA sequences) has not frequently been assessed. Here we hypothesize that an in-depth analysis full circulating landscape could identify specific stronger biomarkers, compared to their corresponding miRNA, for identifying increased CV risk patients with non-alcoholic fatty liver disease (NAFLD)—a clinical unmet need. Plasma were sequenced...
Background : Until recently, the membrane protein ZnT‐1 was studied mainly in context of zinc homeostasis. However, new findings indicate that it acts as an inhibitor L‐type calcium channels. We recently found acute rapid pacing rat atria vivo augments expression ZnT‐1, while knockdown culture can oppose inhibition channels following pacing. This pilot study, first to assess cardiac humans, designed look for possible correlation between atrial and fibrillation. Methods: Right appendage...
Abstract Context Lower fasting ghrelin levels (FGL) are associated with obesity and metabolic syndrome. Objective We aimed to explore the dynamics of FGL during weight loss its adiposity-related manifestations beyond loss. Methods This was a secondary analysis clinical trial that randomized participants abdominal obesity/dyslipidemia 1 3 diets: healthy dietary guidelines (HDG), Mediterranean diet (MED), or green-MED diet, all combined physical activity (PA). Both MED diets were similarly...
Studies of atrial electrophysiology (EP) in rodents are challenging, and available data sparse. Herein, we utilized a novel type bipolar electrode to evaluate the EP through small lateral thoracotomy. In anesthetized rats mice, attached two electrodes right atrium third ventricle. This standard setup enabled high-resolution studies. Moreover, permanent implantation procedure studies conscious freely moving rats. Atrial was evaluated rats, mice (ICR C57BL6 strains), Signal resolution...
Selective pharmacological activation of the adenosine 1 receptor (A<sub>1</sub>R) is a promising new approach to achieve potent block atrioventricular (A-V)–nodal conduction without significant cardiovascular side effects. The purpose present study was evaluate profile INO-8875, highly selective A<sub>1</sub>R agonist, and compare its properties with <i>N</i>-[3(<i>R</i>)-tetrahydrofuranyl]-6-aminopurine riboside (CVT-510), which has already been shown induce negative dromotropic effects...
SYNTAX score is a useful metric determined at the time of invasive coronary angiography (ICA) to assess complexity artery disease, and improves prediction complications percutaneous complex intervention (PCI). We aimed determine whether can be reliably from computed tomography (CCTA) CCTA-derived predict PCI.SYNTAX scores were calculated on per-patient, per-vessel, per-segment basis in 154 consecutive patients who underwent CCTA ICA. PCI 113 was defined by total fluoroscopy contrast...
Abstract: Tacrolimus and cyclosporin A (CsA), the mainstay of preventive therapy for solid organ rejection, may cause various side‐effects, such as hypertension nephrotoxicity. Furthermore, tacrolimus is associated with cardiac hypertrophy. In immediate post‐transplant period, both drugs raise levels Endothelin‐1 (ET), a potent vasoconstrictor; B‐type Natriuretic Peptide (BNP), sensitive marker left ventricular volume overload, which precede echocardiographic changes dysfunction. The aim...
The aim of the current study was to evaluate effect α blockers on cardiac outcomes hypertensive patients who underwent myocardial perfusion imaging (MPI).A retrospective analysis nuclear cardiology laboratory database performed. group included only (n = 19 ,495). cohort divided into three groups - a reference no α-blocker therapy 17 ,053), for benign prostatic hypertrophy (BPH) 1164), and doxazosin hypertension (HTN) 1258). We used Cox proportional regression models examine patient...
We present a case of an adolescent girl with cardiac mass which was characterized as malignant on FDG PET/CT. In addition, PET/CT revealed multiple hypermetabolic pulmonary lesions. The final diagnosis primary angiosarcoma metastases, rare malignancy especially in female patients at this age group. emphasize the potential role neoplasm and literature review uptake benign versus tumors.