A5048882927- Bariatric Surgery and Outcomes
- Pancreatic function and diabetes
- Pluripotent Stem Cells Research
- Cardiac, Anesthesia and Surgical Outcomes
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Diversity and Career in Medicine
- Diabetes Management and Research
- Genetics and Neurodevelopmental Disorders
- Body Contouring and Surgery
- Trauma and Emergency Care Studies
- Diabetes and associated disorders
- Esophageal Cancer Research and Treatment
- Cannabis and Cannabinoid Research
- Global Health Workforce Issues
- Colorectal Cancer Screening and Detection
- Pancreatitis Pathology and Treatment
- COVID-19 and healthcare impacts
- Colorectal Cancer Surgical Treatments
- Health and Medical Research Impacts
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Liver Disease and Transplantation
- Emergency and Acute Care Studies
University of Alberta
2017-2025
McGill University
2020-2025
McMaster University
2020-2025
University of Toronto
2025
University of Calgary
2018-2025
Western University
2018-2025
Dalhousie University
2020-2025
University of British Columbia
2020-2025
University of Alberta Hospital
2022-2024
University of Saskatchewan
2024
Abstract Background Induced pluripotent stem cells (iPSCs) offer potential to revolutionize regenerative medicine as a renewable source for islets, dopaminergic neurons, retinal cells, and cardiomyocytes. However, translation of these cell therapies requires cost-efficient mass manufacturing high-quality human iPSCs. This study presents an improved three-dimensional Vertical-Wheel® bioreactor (3D suspension) expansion protocol with comparison two-dimensional (2D planar) protocol. Methods...
Objective: To provide the largest single-center analysis of islet (ITx) and pancreas (PTx) transplantation. Summary Background Data: Studies describing long-term outcomes with ITx PTx are scarce. Methods: We included adults undergoing (n=266) (n=146) at University Alberta from January 1999 to October 2019. Outcomes include patient graft survival, insulin independence, glycemic control, procedure-related complications, hospital readmissions. Data presented as medians (interquartile ranges,...
Background: Despite ongoing efforts to improve the pancreaticoduodenectomy technique and perioperative care, surgical site infection (SSI) remains a contributor morbidity. Efforts reduce SSI include use of negative pressure wound therapy (NPWT), but studies meta-analyses have been met with conflicting results. We aimed provide an up-to-date large-scale cohort study assess impact NPWT on SSIs. Methods: Utilizing National Surgical Quality Improvement Program database, we included patients...
<h3>Background:</h3> Trauma educational opportunities for general surgery residents in Canada are uncharacterized. We aimed to characterize these and identify factors associated with such opportunities. <h3>Methods:</h3> performed a prospective cross-sectional study characterizing trauma within Canadian programs. Data were collected during 1 summer week winter week. summarized by site season used multivariable modelling evaluate increased likelihood of procedure <h3>Results:</h3> Nine...
Background. Preliminary studies show promise for extrahepatic islet transplantation (ITx). However, clinical comparisons with intraportal ITx outcomes remain limited. Methods. This single-center cohort study evaluates patients receiving or between 1999 and 2018. Primary outcome was stimulated C-peptide level. Secondary were fasting plasma glucose, BETA-2 scores, Multivariable logistic modeling evaluated factors independently associated a composite variable of early graft failure primary...
<h3>Background:</h3> Handover to the trauma team is crucial care. The emergency medical services (EMS) report must be concise, contain key details, and time-limited. Effective handover difficult, often occurring between unfamiliar teams, in chaotic environments, without standardization. We aimed evaluate formats comparison ad-lib communication during handover. <h3>Methods:</h3> conducted a single-blind randomized simulation trial evaluating 2 structured formats. Paramedics randomly assigned...