A5101508111- Nerve injury and regeneration
- Glioma Diagnosis and Treatment
- Histone Deacetylase Inhibitors Research
- Advanced Breast Cancer Therapies
- Mycobacterium research and diagnosis
- Reproductive Health and Technologies
- Pancreatic and Hepatic Oncology Research
- Sperm and Testicular Function
- Tuberculosis Research and Epidemiology
- Microtubule and mitosis dynamics
- Cancer, Hypoxia, and Metabolism
- Mindfulness and Compassion Interventions
- Infectious Diseases and Tuberculosis
- Periodontal Regeneration and Treatments
- South Asian Cinema and Culture
- Mitochondrial Function and Pathology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Gender Roles and Identity Studies
- Amino Acid Enzymes and Metabolism
- Antiplatelet Therapy and Cardiovascular Diseases
- Boron Compounds in Chemistry
- Smart Cities and Technologies
- South Asian Studies and Conflicts
- Sustainability and Climate Change Governance
- Dietary Effects on Health
All India Institute of Medical Sciences
2023-2025
St. John's University
2021-2025
VIT-AP University
2024
SRM University
2023
Dayalbagh Educational Institute
2023
St. John's University
2023
National Cheng Kung University
2020-2022
University of Delhi
2019-2022
Academia Sinica
2021
Medanta The Medicity
2021
Background and objective Alzheimer’s disease (AD) presents profound challenges, significantly impairing quality of life (QOL) for patients increasing the burden on caregivers. This study aims to investigate effectiveness a tailored 12-week yoga intervention in improving individuals with mild moderate AD reducing caregiver (CB). Methods is interventional healthy controls enrolled 30 participants (18 males, 12 females) diagnosed by an expert neurologist. Participants were aged 60 years or...
Abstract Glioblastoma multiforme (GBM) remains one of the most aggressive brain tumors, with a 5-year survival rate only 6%. GBM resistance to standard-of-care therapies underscores need for novel treatment approaches. Metabolic reprogramming is promising hallmark cancer, indicating therapeutic avenue. Lactate dehydrogenase (LDH) upregulated in and adversely affects patients. In this study, we investigated repurposing potential putative LDH inhibitor Stiripentol (STP), an FDA-approved...
The failure of peripheral nerve regeneration is often associated with the inability to generate a permissive molecular and cellular microenvironment for repair. Autologous therapies, such as platelet-rich plasma (PRP) or its derivative growth factors (PRGF), may improve via unknown mechanistic roles actions in macrophage polarization. In current study, we hypothesize that excessive prolonged inflammation might result pro-inflammatory M1 transit anti-inflammatory M2 macrophages large defects....
Epigenetic regulation by histone deacetylases (HDACs) in Schwann cells (SCs) after injury facilitates them to undergo de- and redifferentiation processes necessary support various stages of nerve repair. Although de-differentiation activates the synthesis secretion inflammatory cytokines SCs initiate an immune response during repair, changes either timing or duration prolonged inflammation mediated can affect later associated with repair regeneration. Limited studies have investigated...
Peripheral compressive neuropathy causes significant neuropathic pain, muscle weakness and prolong neuroinflammation. Surgical decompression remains the gold standard of treatment but outcome is suboptimal with a high recurrence rate. From mechanical compression to chemical propagation local inflammatory signals, little known about distinct neuropathologic patterns genetic signatures after nerve decompression. In this study, controllable constriction forces over rat sciatic induces...
Eradicating Human Trafficking: Culture, Law, and Policy by Gabriella Curras DeBELLIS. Leiden/Boston: Brill Nijhoff, 2021. xx + 258 pp. Hardcover: €138.00; USD 166.00. doi: 10.1163/9789004473348 - Volume 14 Issue 1
AbstractExperimental investigation and computational analysis with the DFT approach were done on 4-amino-3-hydroxy naphthalene-1-sulfonic acid (ANSA). Different spectroscopic analyses like NMR, FT-IR, UV-Visible performed. The molecular structure was optimized, wavenumbers of typical vibrational modes calculated using B3LYP method 6-311++G (d, p) basis set. After optimization, bond lengths angles compared experimental ones found well matched, described by RMSD values. Potential energy...
In the healing of our body mind plays vital role. Several researches show that thoughts constantly instructs out immune system. Our perception guides to respond. Investigative instantaneous state becomes important get mind-body interactions. A Significant study congestive heart failure and connection analysis is termed as interaction. It necessary find routine application therapies in patients with failure. has been proved incorporation medicine treatment will help a lot. States Stress or...
<b>Abstract ID 29107</b> <b>Poster Board 440</b> Glioblastoma multiforme (GBM), a grade IV malignant astrocytoma, is highly proliferative primary brain tumor with dismal 5-year survival rate of ∼5%. Current treatment strategies including surgery, radiation, and chemotherapy have limited success due to resistance the standard chemotherapeutic temozolomide (TMZ). Moreover, other drug therapies difficulty permeating blood barrier, invasion in regions makes surgical removal challenging. The dire...
<b>Abstract ID 18966</b> <b>Poster Board 433</b> Currently, pancreatic cancer has a 5-year survival rate of about 11%, making it one the deadliest malignancies. Better treatment strategies are required for due to late diagnosis, early metastasis, and drug resistance. Tumor growth metastasis facilitated by changes in epigenetic profile caused DNA histone alterations. Another key feature is ability elude control suppressors that monitor cell cycle. We aimed investigate combination drugs...
Aims: The current 5-year survival rate of pancreatic cancer is about 10%, making it one the deadliest malignancies. Rapid metastasis, acquired drug resistance, and poor patient prognosis require better therapeutic strategies for ductal adenocarcinoma (PDAC). Non-mutational epigenetic changes evasion cell cycle checkpoints are emerging hallmarks proliferation growth. Combining chemotherapeutic agents in most solid tumors has been successful. HDAC inhibitors CDK4/6 effective but prone to...
Pancreatic cancer is one of the deadliest cancers with 5-year survival rate ~ 10 percent. Late diagnosis, early metastasis, and resistance to therapeutics necessitate a better treatment approach for pancreatic cancer. Alterations in epigenetic profile through DNA histone modifications enable tumor growth metastasis. Evading control suppressors that regulate cell cycle also major hallmark pathophysiology. We aimed study combination therapeutic targeting deacetylase (HDAC) key regulator...
Glioblastoma multiforme (GBM) is a highly proliferative grade IV malignant astrocytoma with 5-year survival rate of ~5%. The current treatment strategies for GBM including surgery, radiation, and chemotherapy face multiple challenges such as resistance to standard chemotherapeutic temozolomide (TMZ), sensitive location, presence blood-brain barrier that hinders permeation various chemotherapeutics. dire need urgency develop new therapeutic the led us explore metabolic vulnerabilities cancer....