Sowmya Gopalan

ORCID: 0000-0003-3117-433X
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Venous Thromboembolism Diagnosis and Management
  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Burkholderia infections and melioidosis
  • Systemic Lupus Erythematosus Research
  • Acute Ischemic Stroke Management
  • Blood groups and transfusion
  • Diabetes Management and Research
  • Hemoglobinopathies and Related Disorders
  • Viral Infections and Vectors
  • SARS-CoV-2 and COVID-19 Research
  • Diabetes and associated disorders
  • Atrial Fibrillation Management and Outcomes
  • Antifungal resistance and susceptibility
  • Infectious Aortic and Vascular Conditions
  • Venomous Animal Envenomation and Studies
  • Complement system in diseases
  • Rabies epidemiology and control
  • Neonatal Health and Biochemistry
  • Inflammatory Biomarkers in Disease Prognosis
  • Aluminum toxicity and tolerance in plants and animals
  • Ultrasound in Clinical Applications
  • Pediatric Hepatobiliary Diseases and Treatments
  • COVID-19 and healthcare impacts

Sri Ramachandra Institute of Higher Education and Research
2012-2025

Directorate of Medicinal and Aromatic Plants Research
2024

Institute of Medical Sciences
2017

Yahoo (United Kingdom)
2015

10.7326/aimcc.2024.0432 article EN cc-by-nc-nd Annals of Internal Medicine Clinical Cases 2025-02-01

Background: From 2019 to 2021, the world was caught in grappling clutches of novel coronavirus, claiming almost 6.9 million lives, thus adding burden on healthcare system. Aim: We aim determine rate co-infections COVID-19-affected individuals, describe their characteristics, and compare mortality rates. Methods: Patients admitted with COVID-19 pneumonia between June 2020 March 2021 who tested positive were identified from hospital RT-PCR records, data collected using information The primary...

10.5455/ijmsph.2025.v11.i1.2 article EN International Journal of Medical Science and Public Health 2025-01-01

Objective: Coronavirus disease 2019 (COVID-19) causes multiorgan dysfunction due to hyperinflammation, dysregulated immune response and cytokine storm. Throughout the COVID-19 pandemic, a number of inflammatory biomarkers, including neutrophil lymphocyte ratio (NLR), have been investigated. The aim this study is assess correlation systemic immune-inflammation index (SII) ferritin percentage (FLPR) with among patients severe COVID-19. Methods: This retrospective observational was conducted...

10.21272/eumj.2025;13(1):198-208 article EN cc-by Eastern Ukrainian Medical Journal 2025-01-01

Accurate diagnosis of glucose-6-phosphate dehydrogenase (G6PD) deficiency is required to avoid the risk acute hemolysis associated with 8-aminoquinoline treatment. The performance BinaxNOW G6PD test compared quantitative spectrophotometric analysis activity was assessed in 356 Plasmodium vivax- infected subjects Brazil, Peru, Thailand, and India. In assay, median 8.81 U/g hemoglobin (range = 0.05–20.19), 11 (3%) identified as deficient. Sensitivity detect deficient 54.5% (6 11), specificity...

10.4269/ajtmh.14-0298 article EN cc-by American Journal of Tropical Medicine and Hygiene 2014-11-11

Background The purpose of this study was to investigate the correlation between computed tomography pulmonary artery obstruction index and parameters functional lung impairment in acute embolism, establish value these prognosticating right ventricular dysfunction 30-day mortality. Methods This included 322 consecutive patients (mean age 45.6 ± 13.2 years, 46.9% male) with free other cardiopulmonary disease, who underwent angiography. Correlations arterial CO2, O2, alveolar-arterial oxygen...

10.1177/0218492317746252 article EN Asian Cardiovascular and Thoracic Annals 2017-12-20

The pattern of bleeding tendencies in dengue and its corellation with platelet count other factors requires clarification.A retrospective study on adults counts less than 100,000 per mm(3) was conducted. Factors associated were analyzed. cohort grouped as severe thrombocytopenia when < 50,000/mm(3) moderate if 50,000-100,000/mm(3) RESULTS: A total 638 patients formed the cohort. 24.1% prevalence observed. Prior anti-platelet drug intake, 70,000/mm(3), international normalized ratio > 2.0,...

10.3855/jidc.5031 article EN cc-by The Journal of Infection in Developing Countries 2015-01-15

Background/Aim: Strict glycaemic control delays the onset as well progression of diabetes related microvascular complications. The major roadblock in achieving target glycated haemoglobin (HbA 1 c) and blood glucose levels is hypoglycaemia. aim this study was to assess clinical characteristics outcomes hypoglycaemia type 2 mellitus (T2DM) hospitalised patients. Methods: This an observational done for nine months T2DM patients who had documented (blood &lt; 70 mg/ dL) during hospital stay....

10.5937/scriptamed55-50079 article EN cc-by SCRIPTA MEDICA 2024-01-01

Background: Arterial and venous thrombosis is one of the major complications coronavirus disease 2019 (COVID-19) infection. Studies have not assessed difference in D-dimer levels between patients who develop those do not. Methods: Our study retrospectively all virus confirmed hospitalized May to September, 2020. Patients were divided into three groups: group 1 with normal < 0.5 g/mL, 2 elevation up six folds, 3 more than six-fold elevation. Statistical analysis was done using SPSS software...

10.14740/jocmr4550 article EN Journal of Clinical Medicine Research 2021-07-01

From the Department of Medicine, Sri Ramachandra Medical College and Research Institute, Chennai, India. The authors declare no conflict interest. Correspondence: Emmanuel Bhaskar, MD, Chennai-600116, E-mail: [email protected].

10.1097/rhu.0b013e318247f3a2 article EN JCR Journal of Clinical Rheumatology 2012-03-01

Increase in the incidence of drug resistance and association with HIV has led to a resurgence tuberculosis. However, tubercular arteritis continues remain rare entity prelidection for thoracic aorta. We report ascending aortic pseudoaneurysm patient already on treatment disseminated tuberculosis who underwent successful surgical repair also review literature pertaining this entity.

10.1136/bcr-2015-211910 article EN BMJ Case Reports 2015-10-06

Paroxysmal nocturnal hemoglobinuria (PNH), a clonal hematopoietic stem cell disorder, arises from the increased sensitivity of red blood cells (RBC) to complement due an acquired deficiency certain glycosylphosphatidylinositol (GPI)-linked proteins, resulting in chronic intravascular hemolysis, arterial and venous thrombotic phenomena, multi-organ damage, failure. We present intriguing case hemolytic anemia, initially suspected be drug-induced, later found associated with PNH, despite being...

10.7759/cureus.67194 article EN Cureus 2024-08-19

Primary hyperparathyroidism (PHPT), often caused by a parathyroid adenoma, is rare but important cause of hypercalcemia. Though PHPT typically presents with symptoms bone pain, kidney stones, and gastrointestinal disturbances, it can occasionally lead to acute pancreatitis. Hypercalcemia-induced pancreatitis, while uncommon, diagnostic challenge due its non-specific overlapping causes. We report the case 60- year-old female who presented persistent epigastric pain ,vomiting loss apetite for...

10.36106/paripex/3708137 article EN PARIPEX-INDIAN JOURNAL OF RESEARCH 2024-10-15

Melioidosis is caused by Burkholderia pseudomallei, a Gram-negative, saprophytic bacillus, commonly found in soil or contaminated water. As infection with this bacterium produces wide variety of clinical manifestations the organism aptly called 'great mimicker'. Even though it non-fastidious and an easily cultivable organism, can be misidentified automated identification systems.A 24-year-old primigravida presented complaints fever myalgia 45 days' duration. She was diagnosed to have...

10.1099/acmi.0.000520.v3 article EN cc-by-nc Access Microbiology 2023-09-01

Diabetics who develop severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) are more likely to have disease, higher odds of intensive care requirement and mortality. Fifteen percent patients new onset hyperglycemia. We studied the comparative outcomes between prior DM, newly detected hyperglycemia assessed role secondary sepsis on RWe performed a r etrospective study confirmed SARS-CoV-2 at tertiary hospital in Chennai, India. Patients were divided as groups (Group 1: With preexisting...

10.4081/monaldi.2022.2037 article EN cc-by-nc Monaldi Archives for Chest Disease 2022-04-12

Presentation of Aspergillus infections the lung is varied. Allergic bronchopulmonary aspergillosis (ABPA) one such presentation in which there hypersensitivity reaction to antigens. It occurs commonly asthmatics and patients with cystic fibrosis. We report a case ABPA 55-year-old male initially evaluated for left cancer who had never been diagnosed asthma.

10.4103/0972-6691.195264 article EN cc-by-nc-sa Indian Journal of Allergy Asthma and Immunology 2016-01-01

Accurate identification of low-risk patients with acute pulmonary embolism (PE) who may be eligible for outpatient treatment or early discharge can have substantial cost-saving benefit. The purpose this study was to derive and validate a prediction model effectively identify PE at low risk short-term mortality, right ventricular dysfunction, other nonfatal outcomes. This analyzed data from 400 consecutive PE. We derived internally validated our rule based on clinically significant variables...

10.1016/j.ihj.2017.09.123 article EN cc-by-nc-nd Indian Heart Journal 2017-10-27

Objectives: This study aimed to assess the outcome and mortality predictors of SARS-CoV-2 infection requiring hospitalization among elderly population. Methods: In this retrospective study, hospitalized people with virologically confirmed were evaluated. Participants divided into three groups mild, moderate, severe based on oxygenation. The primary was death or discharge home. Results: A total 169 patients studied (mean age: 68 years). Apart from respiratory symptoms, other reported symptoms...

10.5812/archcid.112397 article EN Archives of Clinical Infectious Diseases 2021-06-16

Dear Editor, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes adverse outcomes in those with prior medical comorbidities such as diabetes mellitus, hypertension, obesity, chronic kidney disease, and the elderly.[1] Global registries EULAR–COVID-19 database COVID-19 Rheumatology Alliance aim to share of SARS-CoV-2 infection rheumatological disorders.[2] However, there is a lack data from South Asia. Patients rheumatoid arthritis (RA) have higher risk, due disease process...

10.4103/injr.injr_299_20 article EN cc-by-nc Indian Journal of Rheumatology 2021-01-01
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