Xiangjian Chen

ORCID: 0000-0003-3119-4322
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Cardiovascular Function and Risk Factors
  • Peroxisome Proliferator-Activated Receptors
  • Mitochondrial Function and Pathology

Nanjing Medical University
2022

Jiangsu Province Hospital
2022

Although statins are shown to have cardiac pleiotropic effects independent of lowering cholesterol, the underlying mechanism remains unclear. Mitochondrial dysfunction induced by increased fatty acid oxidation (FAO) is culprit in development hypertrophy and dysfunction. This study was explore whether atorvastatin were associated with FAO regulation, a specific focus on carnitine palmitoyltransferase 1 (CPT1). High-fat diet (HFD)-fed mice palmitic (PA)-stimulated neonatal rat primary...

10.1016/j.biopha.2022.114024 article EN Biomedicine & Pharmacotherapy 2022-11-17
Coming Soon ...