A5068357554- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Lung Cancer Diagnosis and Treatment
- Urinary and Genital Oncology Studies
- Head and Neck Cancer Studies
- Oral health in cancer treatment
- Inflammatory Biomarkers in Disease Prognosis
- Spine and Intervertebral Disc Pathology
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- Advances in Oncology and Radiotherapy
- Cancer, Lipids, and Metabolism
- Esophageal Cancer Research and Treatment
- Management of metastatic bone disease
- Lung Cancer Research Studies
- Urological Disorders and Treatments
- Cancer survivorship and care
- Oral Health Pathology and Treatment
- Medical Imaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Nonmelanoma Skin Cancer Studies
- Infectious Diseases and Mycology
Azienda Ospedaliera S.Giuseppe Moscati
2019-2023
University of Catania
2021
European Institute of Oncology
2016-2021
Federico II University Hospital
2017-2021
Istituti di Ricovero e Cura a Carattere Scientifico
2020
University of Naples Federico II
2018
University of Milan
2016-2017
Ospedale D. Cotugno
2017
Fondazione Gimema Onlus
2014
Nagano National Hospital
2000
: Multiparametric magnetic resonance is an established imaging utilized in the diagnostic pathway of prostate cancer. The aim this study to evaluate accuracy and reliability multiparametric (mpMRI) detection clinically significant cancer, defined as Gleason Score ≥ 4 + 3 or a maximum cancer core length 6 mm longer, patients with previous negative biopsy.
A systemic inflammatory marker, the modified Glasgow prognostic score (mGPS), could predict outcomes in non-muscle-invasive bladder cancer (NIMBC). We aimed to investigate predictive power of mGPS oncological HG/G3 T1 NMIBC patients undergoing Bacillus Calmette-Guérin (BCG) therapy.We retrospectively reviewed patient's medical data from multicenter institutions. total 1382 with have been administered adjuvant intravesical BCG therapy, every week for 3 weeks given at 3, 6, 12, 18, 24, 30 and...
The aim of this multi-institutional study was to identify predictors residual high-grade (HG) disease at re-transurethral resection (reTUR) in a large cohort primary T1 HG/Grade 3 (G3) bladder cancer patients. A total 1155 patients with HG/G3 from 13 academic institutions that underwent reTUR within 6 weeks after first TUR were evaluated. Logistic regression analysis performed assess the association predictive factors HG reTUR. Residual found 288 (24.9%) Patients presenting more likely have...
Abstract Aim Radiation-induced oral mucositis (RIOM) is the most frequent side effect in head and neck cancer (HNC) patients treated with curative radiotherapy (RT). A standardized strategy for preventing treating RIOM has not been defined. of this study was to perform a real-life survey on management among Italian RT centers. Methods 40-question administered 25 radiation oncologists working different centers across Italy. Results total 1554 HNC have participating 2021, majority (median 91%)...
Abstract Background Palliative antalgic treatments represent an issue for clinical management and a challenge scientific research. Radiotherapy (RT) plays central role. Techniques such as stereotactic body radiotherapy (SBRT) were largely investigated in several phase 2 studies with good symptom response, becoming widely adopted. However, evidence from randomized, direct comparison of RT SBRT is still lacking. Methods/design The PREST trial was designed interventional study without medicinal...
An accurate and early diagnosis of bladder cancer (BC) is essential to offer patients the most appropriate treatment highest cure rate. For this reason, need be best stratified by class risk factors. We aimed develop a score able better predict outcomes, using serum variables inflammation.A total 1,510 high-risk non-muscle invasive (NMIBC) were included in retrospective observational study. Patients with pathologically proven T1 HG/G3 at first TURBT included. Systemic combined inflammatory...
Objective The aim of this work was to evaluate the impact stereotactic radiosurgery/fractionated radiotherapy with Cyberknife system on local disease control, clinical outcome and toxicity in patients meningioma, according site histological grade lesion. From January 2013 April 2017, 52 intracranial meningiomas were treated system. Twenty-four had undergone previous surgery: 38% gross total resection, 10% subtotal resection; 27 underwent no surgery; 22 a recurrence meningioma. Methods...
BACKGROUND: We aimed to test the hypothesis that immune-modulatory effect of statins may improve survival outcomes in patients with non-muscle invasive bladder cancer (NMIBC). focused on a cohort diagnosed high risk NMIBC, were treated intravesical BCG immunotherapy.METHODS: included at first diagnosis T1 grade NMIBC after transurethral resection (TURB). All procedures performed 18 different tertiary institutions between January 2002 and December 2012. Univariable multivariable models used...
Background Three or four cycles of cisplatin-based chemotherapy is the standard neoadjuvant treatment prior to cystectomy in patients with muscle-invasive bladder cancer. Although NCCN guidelines recommend 4 cisplatin-gemcitabine, three are also commonly administered clinical practice. In this multicenter retrospective study, we assessed a large and homogenous cohort urothelial cancer (UBC) treated cisplatin-gemcitabine followed by radical cystectomy, order explore whether vs. were...
Abstract Hypofractionation for localized prostate cancer treatment is rapidly spreading in the medical community and it supported by radiobiological evidences (lower α/β ratio compared with surrounding tissues). Stereotactic body radiation therapy (SBRT) a technique to administer high doses great precision, which commonly performed CyberKnife (CK) treatment. Since not available at all radiotherapy center, alternative SBRT techniques are such as Volumetric Modulated Arc Therapy (VMAT) Helical...
INTRODUCTION: We aimed to test the hypothesis that immune-modulatory effect of statins may improve survival outcomes in patients with non-muscle invasive bladder cancer (NMIBC). focused on a cohort diagnosed high risk NMIBC, were treated intravesical BCG immunotherapy.PATIENTS AND METHODS: included at first diagnosis T1 grade NMIBC after transurethral resection (TURB). All procedures performed 18 different tertiary institutions between January 2002 and December 2012. Univariable...
In recent years, stereotactic body radiation therapy (SBRT) has gained popularity among clinical methods for the treatment of medium and low risk prostate cancer (PCa), mainly as an alternative to surgery. The hypo-fractionated regimen allows administration high doses in a small number fractions; such fractionation is possible by exploiting different intrinsic radiosensitivity compared with surrounding healthy tissues. addition, SBRT guaranteed better quality life surgery, avoiding risks,...
Purpose:The aim of this retrospective study is to evaluate patient profile, feasibility, and acute toxicity RadioTherapy (RT) delivered by VERO® in the first 20 months clinical activity.Methods: Inclusion criteria: 1) adult patients; 2) limited volume cancer (M0 or oligometastatic); 3) small extracranial lesions; 4) treatment between April 2012 December 2013 5) written informed consent.Two techniques were employed: intensity modulated radiotherapy (IMRT) stereotactic body (SBRT).Toxicity was...