A5014424674- Respiratory and Cough-Related Research
- Asthma and respiratory diseases
- Gastroesophageal reflux and treatments
- Pediatric health and respiratory diseases
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Airway Management and Intubation Techniques
- Pleural and Pulmonary Diseases
- Inhalation and Respiratory Drug Delivery
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pneumonia and Respiratory Infections
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory viral infections research
- Medical Imaging and Pathology Studies
- Infant Health and Development
- Cardiac Arrest and Resuscitation
- Health Sciences Research and Education
- Pharmaceutical industry and healthcare
- Otolaryngology and Infectious Diseases
- Meta-analysis and systematic reviews
- Family and Patient Care in Intensive Care Units
- Clinical practice guidelines implementation
University of Massachusetts Chan Medical School
2014-2025
UMass Memorial Medical Center
2015-2024
UMass Memorial Health Care
2014-2024
Institute of Biomedical Science
2024
Nationwide Children's Hospital
2023
RELX Group (United States)
2016-2020
American College of Chest Physicians
2010-2019
Chandigarh University
2016-2019
King's College London
2018
St Thomas' Hospital
2018
A successful, systematic, anatomic, diagnostic protocol for evaluating patients with chronic cough was presented in 1981. To determine whether it still valid, we prospectively evaluated, over a 22-month interval, 102 consecutive and unselected immunocompetent complaining of an average 53 +/- 97 months (range, 3 wk to 50 yr). Utilizing the modified include prolonged esophageal pH monitoring (EPM), causes were determined 101 (99%) patients, leading specific therapy that successful 98%. Cough...
Six patients with chronic cough, without history of dyspnea or wheezing, had normal base-line spirometry but hyper-reactive airways, as demonstrated methacholine. Maintenance therapy bronchodilators promptly eliminated the cough in all patients. Three to 12 months later was discontinued for three days, returned, and detailed pulmonary-function studies were carried out. Again, values normal, after methacholine one-second forced expiratory volume decreased an average 40 per cent compared 30...
<h3>Background</h3> Cough is the most common complaint for which adult patients seek medical care in United States; however, reason(s) this unknown. <h3>Objectives</h3> To determine whether chronic cough was associated with adverse psychosocial or physical effects on quality of life and elimination specific therapy improved these effects. <h3>Methods</h3> The study design a prospective before-and-after intervention trial serving as their own controls. Study subjects were convenience sample...
It is not clear whether careful history taking with detailed questioning of the characteristics cough diagnostically useful.To determine if character, timing, or complications chronic were helpful in determining its cause.A prospective, descriptive study consecutive, unselected, immunocompetent patients referred to our university outpatient clinic because cough. All evaluated by a previously published and validated systematic diagnostic protocol, self-administered questionnaire, observing...
Nine patients complaining only of chronic cough unknown cause were prospectively studied with prolonged esophageal pH monitoring (EPM) before and after had disappeared as a complaint in order to determine if why gastroesophageal reflux (GER) was causing their coughs. Coughs an average 161 ± 75 days medical therapy for GER. Comparisons pretreatment post-treatment EPM data revealed the following: numbers coughs (p = 0.029), total refluxes 0.001), ⩾ 5 min 0.019), reflux-induced 0.005)...
To compare the incidence of cough in patients with a history angiotensin converting enzyme (ACE) inhibitor-related who received losartan [a type 1 II (Ang II) receptor antagonist], lisinopril (an ACE inhibitor) or hydrochlorothiazide (a diuretic).An international, multicentre, randomized double-blind, parallel-group controlled trial.Outpatient clinics at 20 tertiary care medical centres 11 countries.One hundred and thirty-five uncomplicated primary hypertension were randomly assigned to...
This study is a retrospective survey of the variables that may influence development pneumothorax after thoracentesis. In 30-month period, computer search hospital records identified 342 thoracenteses, which 154 were done with conventional techniques by clinical services, and 188 sonographic guidance. Other factors surveyed included patients' age, sex, underlying pulmonary disease, overall condition; size effusion; type tap (diagnostic or therapeutic); amount (exudate transudate) fluid...
To determine whether the cough of common cold arises from upper respiratory stimuli and antihistamine-decongestant therapy is an effective treatment for this cough, we prospectively evaluated volunteers with uncomplicated colds in a randomized, double-blind, placebo-controlled study. After completing standardized questionnaire undergoing physical examination, throat-culturing, pulmonary function testing, subjects took active drug or identical-appearing placebo 7 days while they kept diary...
An understanding of the anatomic, physiologic, and pathophysiologic aspects cough is necessary to appropriately diagnose treat patients with cough. In majority persons, that acute self-limiting usually secondary a viral upper respiratory tract infection; chronic persistent due bronchitis or postnasal drip. remaining determine cause cough, it systematically consider anatomic locations where receptors afferent nervous pathways are located. Definitive treatment depends on determining its...