A5062293499- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Lipid Membrane Structure and Behavior
- Tea Polyphenols and Effects
- Nanoparticles: synthesis and applications
- Genetic Syndromes and Imprinting
- SARS-CoV-2 detection and testing
- Supramolecular Self-Assembly in Materials
- Bone Tissue Engineering Materials
- Proteins in Food Systems
- Sperm and Testicular Function
- Bone Metabolism and Diseases
- COVID-19 Clinical Research Studies
- Artificial Intelligence in Healthcare
- Biometric Identification and Security
- MXene and MAX Phase Materials
- Electrohydrodynamics and Fluid Dynamics
- Polymer Nanocomposite Synthesis and Irradiation
- Dendrimers and Hyperbranched Polymers
- Face and Expression Recognition
- Seed Germination and Physiology
- Biosensors and Analytical Detection
- interferon and immune responses
Vignana Jyothi Institute of Management
2024
Manipal Academy of Higher Education
2015-2024
Kuvempu University
2024
Context: Asenapine maleate (ASPM) is an antipsychotic drug for the treatment of schizophrenia and bipolar disorder. Extensive metabolism makes oral route inconvenient ASPM.Objective: The objective this study to increase ASPM bioavailability via transdermal by improving skin permeation using combined strategy chemical nano-carrier (transfersomal) based approaches.Materials methods: Transfersomes were prepared thin film hydration method soy-phosphatidylcholine (SPC) sodium deoxycholate (SDC)....
Zn 1− x Eu O ( = 0, 0.25, and 0.5) nanoparticles prepared via co-precipitation method for multifunctional applications.
Aim: To prepare nanostructured lipid carriers (NLCs) loaded with asenapine maleate (ASPM) to increase its oral bioavailability by intestinal lymphatic uptake. Materials & methods: ASPM-NLCs were prepared ultrasound dispersion technique, adopting Design of Experiment approach, and characterized. Results: The optimized formulation exhibited good physicochemical parameters. Differential scanning calorimetry x-ray diffraction studies indicated the amorphized nature ASPM in matrix. In vitro drug...
Abstract Asenapine maleate (ASPM) is a second-generation atypical antipsychotic that approved for treating acute schizophrenia and bipolar disorder in adults by the US FDA. The major downside of ASPM therapy rapid, extensive first-pass hepatic metabolism following its oral administration with very low bioavailability < 2%. In this work, we developed nanoformulations conjugated ligands such as arginine-glycine-aspartic acid (RGD) peptide dendrimers (PDs) intention improving drug targeting...
Abstract Background The purpose of this study was to evaluate the effect nanoparticles (NPs) a plant extract on implant osseointegration in vivo. NPs Cissus quadrangularis (CQ) were synthesized. Twenty Wistar rats included study. test group ( n = 5) had NPs-incorporated, control no incorporation NPs, and sham did not have implants placed. toxicity profile carried out by biochemical analysis before after placement. rate integration assessed using Cone Beam Computed Tomography (CBCT), Digital...
Zinc, an essential micronutrient, is important mediator of sperm function. Supplementation zinc oxide nanoparticle (ZnONPs) to semen cryopreservation medium has shown beneficial effects on function, mainly due its antioxidant and membrane stabilization properties. However, the ZnONPs are known be impermeable. In current study, we explored properties permeable nanoparticles outcome. For 52 liquefied human ejaculates were cryopreserved with chitosan-coated stored in liquid nitrogen for one...