- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiac Health and Mental Health
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Vascular Procedures and Complications
- Cardiovascular and exercise physiology
- COVID-19 Clinical Research Studies
- Genetic Syndromes and Imprinting
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Kawasaki Disease and Coronary Complications
- Hepatitis C virus research
- Parathyroid Disorders and Treatments
- Medical Imaging and Pathology Studies
- Cardiovascular Effects of Exercise
- Central Venous Catheters and Hemodialysis
- Pancreatic function and diabetes
- Iron Metabolism and Disorders
- Heart Failure Treatment and Management
- Palliative and Oncologic Care
- Liver Disease Diagnosis and Treatment
- PARP inhibition in cancer therapy
Hunter Medical Research Institute
2023-2024
John Hunter Hospital
2016-2024
University of Newcastle Australia
2021-2024
Hospital de Santa Maria
2023-2024
Hunter New England Local Health District
2024
Centro Hospitalar Lisboa Norte
2024
University of Lisbon
2024
Institute for Systems Engineering and Computers
2023
University of Coimbra
2014-2023
Pontifical Catholic University of Rio de Janeiro
2022
Abstract Background and Aims Current guidelines recommend 6 hours of solid food 2 clear liquid fasting for patients undergoing cardiac procedures with conscious sedation. There are no data to support this practice, previous single centre studies the safety removing requirements. The objective study was determine non-inferiority a strategy prior catheterisation which require Methods This is multicentre, investigator-initiated, randomised trial conduced in Australia prospective open label...
Objective: To evaluate the effect of relative maximum strength intensity during a conditioning activity on women seated shot put performance. Methods; Nineteen physical active were subjected, at 24-hour intervals and in randomized order, to following conditions: control, 40% one repetition (1RM), 80% 1RM (2 sets 5 repetitions for each condition). The activities consisted contractions performed using vertical bench press apparatus. Three minutes after these contractions, participants executed...
Cardiac catheterization procedures are typically performed with local anaesthetic and proceduralist guided sedation. Various fasting regimens routinely implemented prior to these procedures, noting the absence of prospective evidence, aiming reduce aspiration risk. However, there additional risks from including patient discomfort, intravascular volume depletion, stimulus for neuro-cardiogenic syncope, glycaemic outcomes, unnecessary delayed/cancelled procedures.
To compare the performance of Nanra and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation for estimating glomerular filtration rate in pregnancy against 24 h urine creatinine clearance.Pregnant women had collections with simultaneous serum levels. Measured clearance was compared to two equations: CKD-EPI. Level concordance measured, an a priori bias acceptance ±15 ml/min/1.73 m2.A total 53 synchronous samples were analysed. The -13.4 m2 while CKD-EPI 14.2 m2. Both...
Background: The 1.5mm ‘Baby J’ hydrophilic narrow J tipped wire is a development of the standard 0.035” 3mm peripheral guidewire, designed to improve efficiency transradial coronary procedures by safely navigating small caliber radial arteries aorta. There currently lack evidence comparing procedural success and safety different guidewires used in cardiac procedures. We compared efficacy (intervention - Radifocus™ TERUMO Co., Tokyo, Japan). versus fixed core (FC) (control). Methods:...
Hungry bone syndrome (HBS) is one of the most serious complications following parathyroidectomy for severe hyperparathyroidism. There a lack literature informing treatment and risk factors this condition ideal pre-operative strategy prevention.The primary aims were to examine incidence HBS with calcitriol loading 10 days determine HBS. The secondary rate intravenous calcium replacement in those assess whether cinacalcet removal has increased rates end-stage kidney disease population.We...
Streptococcus oralis is part of the normal flora oropharyngeal, nasal, gastrointestinal and genitourinary tracts. Classically, it shows low pathogenicity virulence, but can very rarely cause meningitis in patients who have undergone dental procedures poor oral hygiene. The purpose this report to highlight importance considering S. as a with A 53-year-old man was admitted emergency department high fever (39.4°C), headache drowsiness. His mouth unhygienic. He diagnosed empiric antibiotics...
This paper presents a new computer-aided design tool specifically developed for the efficient time-domain simulation of strongly nonlinear heterogeneous RF circuits whose stimuli are turned off unknown periods time, hence leaving systems in natural response state. The proposed technique is implemented completely different approach comparison to techniques previously published literature. It based on time-slot division strategy with automatic switching between algorithms along process....
A 26 year old female with a history of cystic fibrosis (homozygous delta F508) and bilateral lung transplant presented bi-frontal headache one month post sinus surgery for chronic sinusitis. The provisional diagnosis was bacterial Although nasal swabs had grown Candida Staphylococcus aureus, …
Pure red cell aplasia is an uncommon cause of anaemia rarely associated with thymoma. A combination immunosuppressive therapy and thymectomy offers a potential cure. Thymectomy alone results in resolution. seventy-three-year-old male Klinefelter syndrome presented progressively increasing shortness breath anaemia. Serological testing supported primary bone marrow pathology, biopsy was performed. pure seen on examination, computed tomography the chest demonstrated performed, histology...
Objective To assess the changes in cardiac hospitalisations, acute coronary syndromes (ACS) and out-of-hospital arrest (OOHCA) during COVID-19 isolation compared with prior time periods an area of low disease incidence. Methods Review all cardiology admissions, non-ST segment elevation myocardial infarction (NSTEMI), ST-segment (STEMI) requiring urgent catheter laboratory activation OOHCA. The 10-week period government-imposed social (23 March–31 May 2020) was same 2018, 2019 a to (6...
Abstract Introduction Cardiac resynchronization therapy (CRT) benefits have been established in patients with heart failure and reduced left ventricular ejection fraction (HFrEF) who a broad QRS remain symptomatic despite optimized medical therapy. Responders typically are female, LBBB broader QRS. It remains uncertain to what extent do non-LBBB complex morphology respond CRT also if there differences among various types of intraventricular conduction delays. Purpose To evaluate the impact...
Abstract Introduction Cardiac rehabilitation (CR) plays a key role in secondary prevention of patients (pts) with cardiovascular (CV) disease. The control CV risk factors is cornerstone comprehensive CR program. Purpose To analyze the impact on factor optimization. Methods Single-center prospective cohort study including consecutive pts enrolled phase 2 program, from 2015 to 2023. Body weight, body mass index (BMI), waist circumference (WC), blood pressure (BP), smoking habits, and...
Abstract Introduction Cardiac rehabilitation (CR) is a structured program that combines exercise and education to help patients (pts) recover from cardiac conditions, in order improve their cardiovascular health enhance overall well-being quality of life. Purpose To compare cardiopulmonary test (CPET) parameters 6 minute walking (6MWT) performance before after CR completion. Methods Single center prospective study consecutive pts completed center-based 2015 April 2023. The included...
Abstract Introduction Acute ST segment elevation myocardial infarction (STEMI) remains a leading cause of premature mortality and morbidity, even in younger patients (pts), with an important loss quality adjusted life years. Recent studies have tried to identify specific characteristics young pts STEMI help stratify risk factors optimize prevention measures. Purpose To characterize evaluate outcomes population STEMI. Methods Retrospective, single-center study consecutive pts, age below 50...
Abstract Introduction Phase 3 Cardiac Rehabilitation (CR) is a maintenance exercise program for which clinical benefits are less well defined comparing to phase 2. Purpose To assess impact of CR on physical activity (PA) levels. Methods A single-center cohort study was conducted, involving patients (pts) who completed 2 at least 6 months prior the and answered International Physical Activity Questionnaire (IPAQ) short form version 2.0. The were divided in groups according progression...
Abstract Introduction As transcatheter aortic valve replacement (TAVR) is increasingly relevant for patients with severe symptomatic stenosis, having a reliable procedure specific risk-prediction tool paramount to provide high-quality care. Surgical scores as the EuroScore II and Society of Thoracic Surgeons (STS) score have been widely used identify high surgical risk in whom percutaneous treatment might be more favorable. However, current literature lacks consensual predictive model...
Abstract Background and Purpose The standard J tip peripheral guidewire used to perform coronary angiography was originally designed for transfemoral access large vascular interventions over 70 years ago. 3mm on the wire is larger than typical radial artery diameter has limited ability navigate smaller tortuous arteries increasing risk of vessel spasm, potentially reducing procedural success. We compared efficacy safety a hydrophilic 1.5mm (intervention - ‘baby wire’) upfront versus fixed...
Abstract Introduction Although implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy (CRT-D) play a life-saving role, patient’s understanding of their device warrants thorough analysis implementation educational programs. Purpose To study expectations regarding ICDs CRT-Ds. Methods Using convenience sampling method, this cross-sectional was conducted on sample 129 patients referred to the pacing clinic or emergency department tertiary hospital, from October...