A5072292164- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiation Detection and Scintillator Technologies
- Prostate Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Advanced X-ray and CT Imaging
- Zeolite Catalysis and Synthesis
- Glioma Diagnosis and Treatment
- Mesoporous Materials and Catalysis
- Gastric Cancer Management and Outcomes
- Head and Neck Cancer Studies
- Breast Lesions and Carcinomas
- Cancer and Skin Lesions
- Esophageal Cancer Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Sarcoma Diagnosis and Treatment
- Pancreatic function and diabetes
- Radiation Dose and Imaging
- Radiation Effects in Electronics
- Advances in Oncology and Radiotherapy
Okayama Medical Center
2001-2025
Osaka University
2004-2025
Seirei Hamamatsu General Hospital
2009-2024
Hokkaido University
2014-2023
Sapporo Medical University
2019-2023
Hokkaido University Hospital
2012-2023
National Hospital Organization
2020-2022
Saitama Cancer Center
2017-2021
Kanagawa Cancer Center
2015-2017
Kanagawa Prefectural Hospital Organization
2015-2017
Image guidance in radiotherapy and extracranial radiosurgery offers the potential for precise radiation dose delivery to a moving tumour. Recent work has demonstrated how locate track position of tumour real-time using diagnostic x-ray imaging find implanted radio-opaque markers. However, treatment plan through gating or beam tracking requires adequate consideration system latencies, including image acquisition, processing, communication delays, control inductance within motor, mechanical...
The zona pellucida is an extracellular glycocalyx that surrounds the growing oocyte and mediates specific biological functions essential to early mammalian development.We have isolated by a novel technique intact zonae pellucidae from murine follicle culture system which mimics in vivo granulosa cell-oocyte interactions.Using radioactive precursors we demonstrated all three proteins, ZP-1,ZP-2, ZP-3, are sulfated glycoproteins.Incubation of with tunicamycin (0.5 pg/ml), antibiotic blocks...
Recently, COL4A1 mutations have been reported in porencephaly and other cerebral vascular diseases, often associated with ocular, renal, muscular features. In this study, we aimed to clarify the phenotypic spectrum incidence of mutations.We screened for 61 patients 10 schizencephaly, which may be similarly caused by disturbed supply leading degeneration, but can distinguished depending on time insult.COL4A1 were identified 15 (21%, 5 schizencephaly), who showed a variety findings, including...
Scatter is a major factor degrading the image quality of cone beam computed tomography (CBCT). Conventional scatter correction strategies require handcrafted analytical models with ad hoc assumptions, which often leads to less accurate removal. This study aims develop an effective method using residual convolutional neural network (CNN).A U-net based 25-layer CNN was constructed for CBCT correction. The establishment model consists three steps: training, validation, and testing. For total...
Objective. Applying carbon ion beams, which have high linear energy transfer and low scatter within the human body, to Spatially Fractionated Radiation Therapy (SFRT) could benefit treatment of deep-seated or radioresistant tumors. This study aims simulate dose distributions spatially fractionated beams (SFB) accurately determine delivered model cell survival rate following SFB irradiation.Approach. Dose are calculated using Triple Gaussian Model. The sensitive volume detector used in...
Abstract BACKGROUND The authors developed fluoroscopic real‐time tumor‐tracking radiation therapy (RTRT) by insertion of a gold marker using bronchofiberscopy to reduce uncertainties in organ motion and set‐up error external radiotherapy for moving tumors. purpose the current study was evaluate RTRT's feasibility lung carcinoma treatment. METHODS three‐dimensional position 1.0‐2.0 mm or near tumor detected two sets fluoroscopies every 0.03 seconds. treatment beam gated irradiate only when...
Abstract The pathogenesis of periarticular osteopenia in rheumatoid arthritis (RA) was investigated by histomorphometry on juxtaarticular bone removed during joint surgery. Twenty areas from 12 RA patients were compared with 14 6 osteoarthritis (OA) patients. There no difference between the 2 groups percent total volume. However, increased formation suggested an increase active osteoid surface that OA. Bone resorption also RA, as evidenced increases versus OA resorptive surface, and number...
Purpose A proton beam therapy (PBT) system has been designed which dedicates to spot-scanning and a gating function employing the fluoroscopy-based real-time-imaging of internal fiducial markers near tumors. The dose distribution treatment time newly real-time-image gated, (RGPT) were compared with free-breathing (FBPT) in simulation. Materials Methods In-house simulation tools planning VQA (Hitachi, Ltd., Japan) used for estimating time. Simulations performed 48 motion parameters (including...
Abstract Aim To prospectively evaluate the efficacy and safety of stereotactic body radiotherapy (SBRT) for patients with previously untreated solitary primary hepatocellular carcinoma (HCC). Methods The main eligibility criteria included following: (1) HCC; (2) no prior treatment (3) Child–Turcotte–Pugh score seven or less; (4) unsuitability refusal surgery radiofrequency ablation (RFA). prescribed dose SBRT was 40 Gy in five fractions. endpoint 3‐year overall survival (OS); secondary...