- Bacterial biofilms and quorum sensing
- Microbial Community Ecology and Physiology
- Water Treatment and Disinfection
- Oral microbiology and periodontitis research
- Wastewater Treatment and Nitrogen Removal
- Legionella and Acanthamoeba research
- Polysaccharides and Plant Cell Walls
- Enzyme Catalysis and Immobilization
- Fecal contamination and water quality
- Probiotics and Fermented Foods
- Vibrio bacteria research studies
- Bacterial Genetics and Biotechnology
- Enzyme Production and Characterization
- Polysaccharides Composition and Applications
- Polymer Surface Interaction Studies
- Analytical chemistry methods development
- Minerals Flotation and Separation Techniques
- Marine Biology and Environmental Chemistry
- Microplastics and Plastic Pollution
- Membrane Separation Technologies
- Planetary Science and Exploration
- Gut microbiota and health
- Protist diversity and phylogeny
- Spaceflight effects on biology
- Biocrusts and Microbial Ecology
University of Duisburg-Essen
2014-2024
IWW Water Centre
1995-2021
Mercator Institute for China Studies
2003
Entwicklungszentrum für Schiffstechnik und Transportsysteme
2001
Ruhr West University of Applied Sciences
1999-2001
Institut für Korrosionsschutz Dresden
1996
Society for Chemical Engineering and Biotechnology
1996
Federal Institute For Materials Research and Testing
1996
French Corrosion Institute
1996
Klinikum Leverkusen
1996
Extracellular polymeric substances are the construction materials for microbial aggregates such as biofilms, flocs ("planktonic biofilms") and sludge. Their major components not only polysaccharides but also proteins in some cases lipids, with minor contents of nucleic acids other biopolymers. In EPS, biofilm organisms can establish stable arrangements function multicellularly synergistic microconsortia. The matrix facilitates retention exoenzymes, cellular debris genetic material; it be...
Pseudomonas aeruginosa is an opportunistic pathogen which causes a variety of diseases, including respiratory tract infections in patients suffering from cystic fibrosis. Therapeutic treatment P. still very difficult because the bacteria exhibit high intrinsic resistance against different antibiotics and, addition, form stable biofilms, e.g. human lung. Several virulence factors are produced by , among them two lectins LecA and LecB, exert cytotoxic effects on epithelial cells presumably...
The genomic relatedness of 573 Pseudomonas aeruginosa strains from environmental and clinical habitats was examined by digesting the genome with rare-cutting enzyme SpeI. Thirty-nine were collected mainly aquatic origin, like rivers, lakes, or sanitary facilities. Four hundred fifty 76 patients cystic fibrosis (CF) treated at four different centers, 25 additional isolates suffering other diseases. Twenty-nine P. environment one CF clinic. Thirty culture collections clinic origin. A common...
The mechanical properties of biofilms and in particular their strength is great importance for both biofilm reactors the removal undesired as cases biofouling biocorrosion. By uniaxial compression measurements, it possible to determine apparent elastic or Young's modulus yield stress parameters stability. This was performed with a recently developed device, using model mucoid strain Pseudomonas aeruginosa SG81. were grown on membrane filters placed nutrient agar medium different...
ABSTRACT Most naturally occurring biofilms contain a vast majority of microorganisms which have not yet been cultured, and therefore we little information on the genetic content these communities. Therefore, initiated work to characterize complex metagenome model drinking water grown rubber-coated valves by employing three different strategies. First, sequence analysis 650 16S rRNA clones indicated high diversity within biofilm communities, with microbes being closely related Proteobacteria...
The Perfect Slime presents the latest state of knowledge and a wide range aspects extracellular polymeric substances (EPS) matrix - from ecological health to antifouling perspectives. book brings together all current material in order expand our understanding functions, properties characteristics as well possibilities strengthen or weaken it.The EPS represents immediate environment which biofilm organisms live. From their point view, this has paramount advantages. It allows them stay for...
Extracellular polymeric substances (EPSs) are involved in both detrimental and beneficial consequences of microbial aggregates such as biofilms, flocs biological sludges. In biofouling, they responsible for the increase friction resistance, change surface properties hydrophobicity, roughness, colour, etc. biocorrosion metals by their ability to bind metal ions. bioweathering, contribute complexing dissolution minerals. The EPSs represent a sorption site pollutants heavy ions organic...
Pseudomonas aeruginosa secretes a variety of hydrolases, many which contribute to virulence or are thought play role in the nutrition bacterium. As most studies concerning extracellular enzymes have been performed on planktonic cultures non-mucoid P. strains, knowledge potential these biofilm formation mucoid (alginate-producing) remains limited. Here we show that produces hydrolases during growth. Overexpression lipases LipA and LipC, esterase EstA proteolytic elastase LasB from plasmids...
As an opportunistic human pathogen Pseudomonas aeruginosa is able to cause acute and chronic infections. The biofilm mode of life significantly contributes the growth persistence P. during infection process mediates pathogenicity bacterium. Within a mucoid strains simultaneously produce secrete several hydrolytic enzymes extracellular polysaccharide alginate. focus current study was interaction between lipase LipA alginate, which may be physiologically relevant in biofilms aeruginosa....
Extracellular polymeric substances (EPS) are the major structural and functional components of microbial biofilms. The aim this study was to establish a method for EPS isolation from biofilms thermoacidophilic archaeon, Sulfolobus acidocaldarius, as basis analysis. Biofilms S. acidocaldarius were cultivated on surface gellan gum-solidified Brock medium at 78°C 4 days. Five extraction methods compared, including shaking biofilm suspensions in phosphate buffer, cation-exchange resin (CER)...