- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Bladder and Urothelial Cancer Treatments
- Diverticular Disease and Complications
- Renal cell carcinoma treatment
- Systemic Sclerosis and Related Diseases
- Adrenal and Paraganglionic Tumors
- Pituitary Gland Disorders and Treatments
- Hormonal Regulation and Hypertension
- Urinary and Genital Oncology Studies
- Abdominal Surgery and Complications
- Infectious Disease Case Reports and Treatments
- Biliary and Gastrointestinal Fistulas
- Esophageal and GI Pathology
- Sarcoma Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Ureteral procedures and complications
- Cardiac tumors and thrombi
- MicroRNA in disease regulation
- Streptococcal Infections and Treatments
- Sexual function and dysfunction studies
- Kidney Stones and Urolithiasis Treatments
- Tuberous Sclerosis Complex Research
- Urinary Tract Infections Management
- Prostate Cancer Diagnosis and Treatment
University of Perugia
2017-2024
Santa Maria Nuova Hospital
2022
Azienda Ospedaliera di Perugia
2017
Abstract The lack of symptoms at the early stages clear cell renal carcinoma (ccRCC) allows tumour to metastasize, leading a dramatic reduction in patient survival. Therefore, we studied and set up method based on urinary microRNAs (miRNAs) for diagnosis ccRCC. First, miRNA expression ccRCC specimens kidney tissues from healthy subjects (HSs) was investigated through analysis data banks validated by comparing miRNAs adjacent non-cancerous tissue RT-qPCR. Subsequently, developed an algorithm...
Abstract Surgical Site Infection (SSI) is the most frequent source of infection in surgical patients and second cause hospital-acquired infection. The primary aim this prospective study was to compare SSI occurrences between minimally invasive surgery (MIS) open urological surgery. Secondly, perioperative outcomes were evaluated two different approaches. A consecutive group 60 undergoing prospectively enrolled a single high-volume center May October 2018. We included procedures that...
Renal artery embolization is performed before radical nephrectomy (RN) for renal mass in order to induce preoperative infarction and facilitate surgical intervention through decrease of intraoperative bleeding. Moreover, metastatic cancer it seems stimulate tumour-specific antibodies, even if no established benefits clinical response or survival have been reported. The role (PRAE) management masses has often debated its real are still unclear. Nevertheless, huge complex masses, which...
PD-L1 represents a crucial immune checkpoint molecule in the tumor microenvironment, identified as key target for cancer immunotherapy. A correlation between and EMT-related genes expression various human cancers has been suggested.By ScreenCell filtration, digital droplet PCR confocal microscopy analysis, we aimed to investigate of EMT/invasive (TWIST1, ZEB1, VIMENTIN, TIMP2) circulating cells (CTCs) collected from blood non-muscle-invasive bladder (NMIBC) patients, assessing prognostic...
Abstract Fournier’s gangrene is a potentially fatal emergency condition characterized by necrotizing fasciitis and supported an infection of the external genital, perineal perianal region, with rapid progressive spread from subcutaneous fat tissue to fascial planes. In this case report, 52-year-old man, history hepatitis C-virus (HCV)-related chronic liver disease cocaine use disorder for which he was receiving methadone maintenance therapy, admitted Emergency Department necrotic involving...
Angiosarcoma (AS) is an aggressive malignant tumour of endothelial origin, most frequently compelling the skin. The kidney a rare site primary occurrence AS with quite challenging diagnosis and poor prognosis, mainly due to its raw metastasising power. We described our first case treatment. A comprehensive literature review in this field also carried out.
Several studies have shown the consequences of COVID-19 pandemic on perceived stress different populations, but none them analyzed urological patients who underwent elective surgery.We enrolled prospectively surgery between March and October 2020. A survey 4-item Perceived Stress Scale (PPS-4) questionnaire were administered at hospital admission. Demographic medical history data also collected. Uni- multivariate analyses performed to identify independent predictors higher PSS-4 values...
Primary renal extra-skeletal Ewing sarcoma is a rare neoplasm, often metastatic at diagnosis, and with poor outcome. A multimodal approach the treatment of choice in this aggressive neoplasm. We present case primary 45-year-old woman who underwent tumor resection without clear margins. After no response to first cycle chemotherapy, we documented an early onset local recurrence. The patient refused any other died four months after surgery.
Background: Voiding and sexual dysfunction in Multiple Sclerosis represent the most devastating dimensions of disease.Pharmacological treatment voiding could improve life patients affected by disease.We investigated effects Onabotulinum toxin A intradetrusor injections on urinary symptoms dysfunction, psychological status women with refractory overactive bladder.Methods: 41 underwent neurologic urologic clinical evaluations were administered Female Sexual Function Index, Incontinence-Quality...
Purpose: Prostatourethrorectal fistula (PURF) is an uncommon complication resulting from surgery, radiation or trauma (1). The most common therapeutic management transperineal surgery Transabdominal approach less used and limited to large fistulae needing cystectomy rectal resection aim of this study was show original robotic technique conservative treatment for PURF. Materials Methods: A 75 years old man referred recurrent UTI, pneumaturia urinary loss rectum due PURF arising after TURP...
Bladder cancer (BC) is one of the most expensive lifetime cancers to treat because high recurrence rate, repeated surgeries, and long-term cystoscopy monitoring treatment. The lack an accurate classification system predicting risk or progression leads search for new biomarkers strategies. Our pilot study aimed identify a prognostic gene signature in circulating tumor cells (CTCs) isolated by ScreenCell devices from muscle invasive non-muscle BC patients. Through PubMed database Cancer Genome...
Introduction: Genital condylomatosis is a highly contagious disease caused by the human papilloma virus (HPV). The aim of this prospective multicentre study was to evaluate safety and efficacy Holmium:YAG (yttrium-aluminium-garnet) laser in treatment genital intra-urethral warts; secondary assess patients’ postoperative satisfaction cosmetic results. Methods: From December 2016 March 2019, patients with warts were prospectively enrolled three hospitals. inclusion criteria male gender, age...
You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Neurogenic Voiding Dysfunction1 Apr 20131715 URINARY SYMPTOMS AND SEXUAL DYSFUNCTION IN PATIENTS AFFECTED BY MULTIPLE SCLEROSIS Silvia Proietti, Marilena Gubbiotti, Jacopo Adolfo Rossi de Vermandois, Massimo Porena, and Antonella Giannantoni ProiettiSilvia Proietti Milano, Italy More articles by this author , GubbiottiMarilena Gubbiotti Perugia, VermandoisJacopo Vermandois PorenaMassimo Porena GiannantoniAntonella View...
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Incontinence: Evaluation (Urodynamic Testing)1 Apr 2018MP27-11 OVERACTIVE BLADDER, URINARY INCONTINENCE AND DEPRESSION Antonella Giannantoni, Marilena Gubbiotti, Ettore Mearini, Pierfrancesco Maria Balducci, and Jacopo Adolfo Rossi de Vermandois GiannantoniAntonella Giannantoni More articles by this author , GubbiottiMarilena Gubbiotti MeariniEttore Mearini BalducciPierfrancesco Balducci...