Simona Hapca

ORCID: 0000-0003-3148-9657
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About
Contact & Profiles
Research Areas
  • Soil and Unsaturated Flow
  • Diabetes Management and Research
  • Soil Geostatistics and Mapping
  • Diabetes Treatment and Management
  • Bacterial biofilms and quorum sensing
  • Mineral Processing and Grinding
  • Microbial bioremediation and biosurfactants
  • Intensive Care Unit Cognitive Disorders
  • Microbial Community Ecology and Physiology
  • Dementia and Cognitive Impairment Research
  • Soil Carbon and Nitrogen Dynamics
  • Chronic Kidney Disease and Diabetes
  • Peptidase Inhibition and Analysis
  • Heart Failure Treatment and Management
  • Diabetes and associated disorders
  • Nematode management and characterization studies
  • Frailty in Older Adults
  • Geochemistry and Geologic Mapping
  • Clay minerals and soil interactions
  • Medical Image Segmentation Techniques
  • Plant Pathogens and Fungal Diseases
  • Lichen and fungal ecology
  • Diabetes Management and Education
  • Mycorrhizal Fungi and Plant Interactions
  • Pancreatic function and diabetes

University of Stirling
2019-2023

University of Dundee
2016-2023

Genomics (United Kingdom)
2018-2023

Ninewells Hospital
2019-2023

Abertay University
2009-2018

Cognitive impairment of various kinds is common in older people admitted to hospital, but previous research has usually focused on single conditions highly-selected groups and rarely examined associations with outcomes. This study prevalence outcomes cognitive a large unselected cohort aged 65+ an emergency medical admission. Between January 1, 2012, June 30, 2013, admissions general hospital acute unit underwent structured specialist nurse assessment (n = 10,014). We defined 'cognitive...

10.1186/s12916-017-0899-0 article EN cc-by BMC Medicine 2017-07-21

To investigate the association between visit-to-visit HbA1c variability and cardiovascular events microvascular complications in patients with newly diagnosed type 2 diabetes.This retrospective cohort study analyzed from Tayside Fife Scottish Care Information-Diabetes Collaboration (SCI-DC) who were observable diagnosis of diabetes had at least five measurements before outcomes evaluated. We used previously reported score (HVS), calculated as percentage number changes >0.5% (5.5 mmol/mol)...

10.2337/dc19-0823 article EN Diabetes Care 2019-11-14

There are few observational studies evaluating the risk of AKI in people with type 2 diabetes, and even fewer simultaneously investigating CKD this population. This limits understanding interplay between diabetes compared nondiabetic population.In retrospective, cohort study participants or without we used electronic healthcare records to evaluate rates various statistical methods determine their relationship status further renal function decline.We followed 16,700 (9417 7283 controls...

10.1681/asn.2020030323 article EN Journal of the American Society of Nephrology 2020-09-18

The characterization of the dispersal populations non-identical individuals is relevant to most ecological and epidemiological processes. In practice, movement quantified by observing relatively few individuals, averaging estimate rate population as a whole. Here, we show that this can lead serious errors in predicted if disperse at different rates. We develop stochastic model for diffusion heterogeneous populations, inspired parasitic nematode Phasmarhabditis hermaphrodita . Direct...

10.1098/rsif.2008.0261 article EN Journal of The Royal Society Interface 2008-08-15

There is currently a significant need to improve our understanding of the factors that control number critical soil processes by integrating physical, chemical and biological measurements on soils at microscopic scales help produce 3D maps related properties. Because technological limitations, most can be carried out only exposed surfaces or 2-dimensional cuts through samples. Methods developed properties based spatial sequences 2D maps. In this general context, objective research described...

10.1371/journal.pone.0137205 article EN cc-by PLoS ONE 2015-09-15

To assess the real-world cardiovascular (CV) safety for sulfonylureas (SU), in comparison with dipeptidyl peptidase 4 inhibitors (DPP4i) and thiazolidinediones (TZD), through development of robust methodology causal inference a whole nation study.A cohort study was performed including people type 2 diabetes diagnosed Scotland before 31 December 2017, who failed to reach HbA1c 48 mmol/mol despite metformin monotherapy initiated second-line pharmacotherapy (SU/DPP4i/TZD) on or after 1 January...

10.2337/dc22-1238 article EN Diabetes Care 2023-03-21

Abstract. Despite the importance of fungi in soil ecosystem services, a theoretical framework that links management strategies with fungal ecology is still lacking. One key challenges to understand how complex geometrical shape pores affects spread and species interaction. Progress this area has long been hampered by lack experimental techniques for quantification. In paper we use X-ray computed tomography quantify characterize pore geometry at microscopic scales (30 μm) are relevant soil....

10.5194/bg-7-3731-2010 article EN cc-by Biogeosciences 2010-11-18

SUMMARY Entomopathogenic nematodes (EPN) are soil-transmitted parasites and their foraging strategies believed to range from ‘ambush’ ‘cruise’ foragers. However, research on behaviour has not considered the natural habitat of these nematodes. We hypothesized that EPN would be influenced by soil quality tested this hypothesis using 2 species Steinernema carpocapsae (an ‘ambusher’) Heterorhabditis megidis (a ‘cruiser’) in contrasting habitats, sand peat. As predicted previous studies, most S....

10.1017/s0031182009991326 article EN Parasitology 2009-10-16

Recent advances in imaging techniques offer the possibility of visualizing three‐dimensional structure soils at very fine scales. To make use such information, a thresholding process is commonly implemented to separate image into solid particles and pores. Despite multitude algorithms available, their performance being challenged by complexity soil structure. Experience shows that, improve performance, existing methods require significant input from skilled operator, making subjective. In...

10.2136/vzj2012.0172 article EN cc-by-nc-nd Vadose Zone Journal 2013-06-21

Abstract Background Diabetic retinopathy (DR) is a major sight-threatening microvascular complication in individuals with diabetes. Systemic inflammation combined oxidative stress thought to capture most of the complexities involved pathology diabetic retinopathy. A high level neutrophil–lymphocyte ratio (NLR) an indicator abnormal immune system activity. Current estimates association NLR diabetes and its complications are almost entirely derived from cross-sectional studies, suggesting that...

10.1186/s12916-023-02976-7 article EN cc-by BMC Medicine 2023-08-10
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