A5058665744- Motor Control and Adaptation
- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Hemispheric Asymmetry in Neuroscience
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Neuroscience and Neural Engineering
- Tactile and Sensory Interactions
- Spatial Neglect and Hemispheric Dysfunction
University of California, San Francisco
2024
University of California, Berkeley
2020-2022
Bioengineering Center
2020-2021
Neurophysiological studies in humans and nonhuman primates have revealed movement representations both the contralateral ipsilateral hemispheres. Inspired by clinical observations, we ask if this bilateral representation differs for left right Electrocorticography was recorded human participants during an instructed-delay reaching task, with movements produced either or arm. Using a cross-validated kinematic encoding model, found stronger hemisphere, effect that present preparation amplified...
ABSTRACT Deep brain stimulation (DBS) has garnered widespread use as an effective treatment for advanced Parkinson’s Disease (PD). Conventional DBS (cDBS) provides electrical to the basal ganglia at fixed amplitude and frequency, yet patients’ therapeutic needs are often dynamic with residual symptom fluctuations or side-effects. Adaptive (aDBS) is emerging technology that modulates respect real-time clinical, physiological, behavioral states, enabling therapy dynamically align...
Pronounced activity is observed in both hemispheres of the motor cortex during preparation and execution unimanual movements. The organizational principles bi-hemispheric signals functions they serve throughout planning remain unclear. Using an instructed-delay reaching task monkeys, we identified two components population responses spanning PMd M1. A “dedicated” component, which segregated at level individual units, emerged preparation. It was most prominent following movement when M1...
ABSTRACT Pronounced activity is observed in both hemispheres of the motor cortex during preparation and execution unimanual movements. The organizational principles bi-hemispheric signals functions they serve throughout planning remain unclear. Using an instructed-delay reaching task monkeys, we identified two components population responses spanning PMd M1. A “dedicated” component, which segregated at level individual units, emerged preparation. It was most prominent following movement when...
ABSTRACT Neurophysiological studies in humans and non-human primates have revealed movement representations both the contralateral ipsilateral hemisphere. Inspired by clinical observations, we ask if this bilateral representation differs for left right hemispheres. Electrocorticography (ECoG) was recorded human participants during an instructed-delay reaching task, with movements produced either or arm. Using a cross-validated kinematic encoding model, found stronger hemisphere, effect that...