Marek Chojnowski

ORCID: 0000-0003-3156-0740
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About
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Research Areas
  • Systemic Sclerosis and Related Diseases
  • Musculoskeletal synovial abnormalities and treatments
  • Cardiac Imaging and Diagnostics
  • Skin Diseases and Diabetes
  • Diabetic Foot Ulcer Assessment and Management
  • Osteomyelitis and Bone Disorders Research
  • Inflammatory Myopathies and Dermatomyositis
  • Medical Imaging Techniques and Applications
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Genital Health and Disease
  • transportation and logistics systems
  • Thyroid Cancer Diagnosis and Treatment
  • Cardiac Structural Anomalies and Repair
  • Elbow and Forearm Trauma Treatment
  • Globalization, Economics, and Policies
  • Economic and Fiscal Studies
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • ECG Monitoring and Analysis
  • Pressure Ulcer Prevention and Management
  • Infrared Thermography in Medicine
  • Cardiovascular Function and Risk Factors
  • Cardiac electrophysiology and arrhythmias
  • Heterotopic Ossification and Related Conditions
  • Bone and Joint Diseases
  • Esophageal Cancer Research and Treatment

The Maria Sklodowska-Curie National Research Institute of Oncology
2019-2023

National Institute of Geriatrics, Rheumatology and Rehabilitation
2016-2022

Center for Rheumatology
2021

Centrum Onkologii
2020

Central Clinical Hospital
2016-2019

Medical University of Warsaw
2014-2017

Background and aims: Systemic sclerosis (SSc) is an autoimmune, rare multisystem chronic disease that still not well-understood aetiologically challenging diagnostically. In the literature, there are ever-increasing assumptions regarding epigenetic mechanisms involved in SSc development; one of them circulating microRNAs. Many regulate TLR pathways significant autoimmune balance. The aim this study was to determine profile expression selected microRNAs patients, including miR-126, -132,...

10.3390/ijms231810731 article EN International Journal of Molecular Sciences 2022-09-14

Radioguided surgery using 68-gallium labelled somatostatin analogues is a promising method for detection of small, intra-abdominal, neuroendocrine neoplasm (NEN). However, due to high background activity (physiological uptake in e.g. spleen, adrenal glands and kidneys) tumours the tail body pancreas might be impossible detect with hand-held gamma probe. Therefore new concept intraoperative PET/CT scan resected tissue can helpful determining whether tumour has been excised within margins...

10.5603/nmr.2014.0028 article EN cc-by-nc-nd Nuclear Medicine Review 2014-07-31

Recent studies point to analysis of T-wave alternans as a promising indicator an increased risk life-threatening ventricular arrhythmias. In this study the occurrence in high-resolution ECGs recorded during exercise stress test and scintigraphic tests (SPECT) patients with ischemic heart disease was examined.The group consisted 33 after myocardial infarction. infarction low left ejection fraction correlations 70% between results SPECT 60% were found.In but high respectively 39% 48%. The...

10.5114/aoms.2013.39939 article EN cc-by-nc-sa Archives of Medical Science 2014-09-12

Radionuclide synovectomy (RSV) is a form of minimally invasive treatment persistent joint inflammation. The procedure has high safety profile and the occurrence serious adverse events, such as full-thickness skin radiation necrosis, rare. Less severe while more common, are usually benign self-limiting. We present two cases low-grade beta burns that developed after RSV, despite proper injection technique. potential long-term risk exposure also discussed, with reference to historical...

10.5114/reum.2018.76905 article EN cc-by-nc-sa Reumatologia/Rheumatology 2018-06-30

Clinical experience and basic science studies show that Negative Pressure Wound Therapy (NPWT) is a promising yet still under-used treatment method for patients with diabetic foot syndrome (DFS). Despite its advantages, it may carry the risk of serious side effects if indications contraindications are not strictly observed. The aim this article to discuss myths facts about NPWT in conditions such as: inadequate blood supply, insufficient wound debridement, osteomyelitis or necessity monitor...

10.18487/npwtj.v2i1.13 article EN cc-by Negative Pressure Wound Therapy Journal 2015-04-01

Pigmented villonodular synovitis (PVNS) is a rare disease that has clinical and histopathological characteristics of both benign proliferative disorder chronic inflammatory process the synovial tissue. The primary mode treatment surgery followed by an adjuvant radiotherapy; however, risk recurrence significant (40-70%). Several publications suggest TNF-α inhibitors might be option. We present case 29-year-old female diagnosed with PVNS knee joint, refractory to 3 radionuclide synovectomies....

10.5114/reum.2021.110601 article EN cc-by-nc-sa Reumatologia/Rheumatology 2021-11-07

The objective of this study was to semiquantitatively assess the degree myocardial fluorodeoxyglucose (FDG) uptake in glucose-loaded viability positron emission tomography/computed tomography (PET/CT) scans, calculate background index, and correlate index with image quality assessed on basis visual qualitative assessment.The FDG-PET/CT carried out 69 non-diabetic patients, who had known coronary artery disease, by intravenous injection 250 ± 70 MBq (range: 180-320 MBq) FDG. Images were...

10.5603/nmr.a2017.0010 article EN cc-by-nc-nd Nuclear Medicine Review 2017-05-25

Purpose Clinical symptoms and electrocardiographic changes in patients with Takotsubo syndrome can be similar to myocardial infarction. The aim of the study was assess impact SPECT/CT imaging on diagnosis management (TTS). Methods Gated single photon emission computed tomography (SPECT)/CT after injection 99Tc-MIBI resting conditions performed 27 TTS using dual-head Symbia T6SPECT/CT hybrid device. CT data were used for attenuation correction SPECT images risk coronary artery disease basis...

10.2459/jcm.0000000000000820 article EN Journal of Cardiovascular Medicine 2019-05-25

<h3>Background:</h3> Radionuclide synovectomy (RSV) is a form of minimally invasive treatment persistent joint inflammation. Primary indication for RSV hypertrophic synovitis refractory to disease-modifying anti-rheumatic drugs (DMARDs), whether synthetic or biological, and intraarticular steroid injections. This procedure has high rate success with low adverse events complications in properly selected patients. Moreover, due bactericidal properties the radiocolloids, risk infection after...

10.1136/annrheumdis-2019-eular.7064 article EN Annals of the Rheumatic Diseases 2019-06-01

This article presents a patient with long history of type 1 diabetes mellitus complicated neuropathy and Charcot disease.The most common cause neuropathic osteoarthropathy, called is poorly controlled diabetes.The clinical picture characterized by considerable edema, redness increased skin temperature relatively slight pain due to injury nerve fibers responsible for sensation.The differential diagnosis should include bacterial or autoimmune arthritis, arthritis associated gout as well venous...

10.15557/jou.2016.0022 article EN cc-by-nc-nd Journal of Ultrasonography 2016-04-30

Radiosynovectomy (RSV) is a minimally invasive method of treating and controlling joint inflammation refractory to conventional pharmacotherapy. It consist in intraarticular injection radioactive colloids which irradiate the inflamed synovial membrane cause its subsequent involution. Despite fact that hip involvement quite common systemic inflammatory arthropathies, RSVs are rarely performed. The aim this paper assess safety efficacy radioisotope treatment.We retrospectively analyzed effects...

10.5114/reum/166608 article EN cc-by-nc-sa Reumatologia/Rheumatology 2023-07-02

We report a case of 67-year-old man suffering from psoriatic arthritis, type 2 diabetes and diabetic foot syndrome. The patient presented symptoms inflammation the right ankle joint. Scintigraphic imaging with radiolabeled white blood cells was performed to differentiate whether related arthritis or After revealing that, inflammatory process restricted only articular space subtalar joint, diagnosed exacerbation qualified for radionuclide synovectomy. In patients coexistent syndrome it is...

10.5603/nmr.2017.0016 article EN cc-by-nc-nd Nuclear Medicine Review 2017-05-25
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