A5045117836- Thyroid Cancer Diagnosis and Treatment
- Nutrition and Health Studies
- Hypothalamic control of reproductive hormones
- Ovarian cancer diagnosis and treatment
- Radiopharmaceutical Chemistry and Applications
- PI3K/AKT/mTOR signaling in cancer
- Neuroendocrine Tumor Research Advances
- Metabolism, Diabetes, and Cancer
- Medical Imaging Techniques and Applications
- Estrogen and related hormone effects
- Cancer Cells and Metastasis
- Lung Cancer Research Studies
- Adrenal and Paraganglionic Tumors
- Gout, Hyperuricemia, Uric Acid
- S100 Proteins and Annexins
- Ovarian function and disorders
- Cancer-related Molecular Pathways
- TGF-β signaling in diseases
- Cancer, Hypoxia, and Metabolism
- Liver physiology and pathology
- Prostate Cancer Treatment and Research
- Alcohol Consumption and Health Effects
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Bone health and treatments
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
The Maria Sklodowska-Curie National Research Institute of Oncology
2021-2024
Central Clinical Hospital
2021
Medical University of Lodz
2009
The guidelines Thyroid Cancer 2022 are prepared based on previous Polish recommendations updated in 2018. They consider international - American Association (ATA) 2015 and National Comprehensive Network (NCCN); however, they adapted according to the ADAPTE process. strength of quality scientific evidence assessed GRADE system ATA NCCN recommendations. core changes made is inclusion results those studies that have already proven themselves prospectively. These extensions allow de-escalation...
Background: GnRH-II has been shown to exert a strong antiproliferative action on tumors of the female reproductive system. The data so far reported effects prostate cancer growth are controversial. Moreover, it is still unclear through which receptor [type I or type II GnRH-receptor (GnRH-R)] might modulate cell proliferation. Objective: objective this work was investigate whether affect proliferation cells and identify GnRH-R peptide its activity. Design: We investigated then transfected...
Advances in the diagnosis and treatment of adrenocortical carcinoma (ACC), along with development new therapeutic diagnostic methods, have prompted a team experts to formulate first Polish guidelines for managing ACC. This article presents recommendations resulting from discussion specialists various medical specialities, who participated series online meetings aimed at developing consistent effective under National Oncology Strategy. These aim optimise ACC Poland through coordinated efforts...
Abstract Introduction: The Duonen project aims to test the efficacy of tandem PRRT therapy neuroendocrine tumors with DOTA-TATE labeled 177 Lu and 90 Y radionuclides compared conventional mono-radionuclide using a fixed activity 7.4 GBq. paper presents dosimetric procedure used preliminary results obtained from treatment 40 patients 113 cycles therapy. Material Methods: Dosimetry is performed QDose program based on 4 SPECT/CT scans 5 blood samples taken for bone marrow dosimetry. Calculation...
The aim of this study was to assess the incidence point mutations in RAS oncogenes papillary thyroid carcinoma (PTC). Tumour specimens were obtained from 29 PTCs. fragments exons 1 and 2 family (H-RAS, K-RAS, N-RAS) amplified then, detected by SSCP and/or RFLP analysis. Several DNA samples directly sequenced confirm results. Two found (GAA/CAA at codon 31 K-RAS CAA/CAC 61 N-RAS oncogene). These data results previous studies, showing that are more rarely PTC than follicular neoplasms....
Type 2 diabetes is one of the most common diseases in aging population; however, data concerning correlates age-advanced individuals are limited. The study aimed to identify socioeconomic representative groups oldest-old (≥ 85 years) and younger (65 84 Polish Caucasian seniors.PolSenior a multicentre, population-based conducted Poland. Fasting plasma glucose levels from detailed medical questionnaires were obtained 2128 male 1961 female participants aged ≥ 65 years. Multivariate logistic...
Transforming growth factor beta 1 (TGFB1) stimulates the production of various extracellular matrix components; at same time, it inhibits degradation. These actions TGFB1 contribute to tissue repair, however, an altered expression can be a causative fibrosis processes, including thyroid which follows chronic thyroiditis. The aim our study was examine potential correlation between gene level in fine-needle aspiration biopsy (FNAB) specimens and gland two types lesions. Fibrosis assessed,...
The data demonstrating a correlation between sonographic markers of malignancy thyroid cancer (TC) and its genetic status are scarce. This study aimed to assess whether the addition analysis at preoperative step TC patients’ stratification could aid their clinical management. material consisted formalin-fixed paraffin-embedded tumor fragments 49 patients who underwent thyroidectomy during early stages papillary (PTC). Tumor DNA RNA were subjected next-generation sequencing (NGS) on Ion...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
GnRH-II has been shown to exert a strong antiproliferative action on tumors of the female reproductive system. The data so far reported effects prostate cancer growth are controversial. Moreover, it is still unclear through which receptor [type I or type II GnRH-receptor (GnRH-R)] might modulate cell proliferation. objective this work was investigate whether affect proliferation cells and identify GnRH-R peptide its activity. We investigated then transfected PC3 with small interfering RNA...