A5026382883- Thyroid Cancer Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Bone health and osteoporosis research
- Bone health and treatments
- BRCA gene mutations in cancer
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Anomalies
- Medical Imaging Techniques and Applications
- Growth Hormone and Insulin-like Growth Factors
- Medical Imaging and Pathology Studies
- Radiopharmaceutical Chemistry and Applications
- Neuroendocrine Tumor Research Advances
- Cardiac Imaging and Diagnostics
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
- Ultrasound and Hyperthermia Applications
- Radioactive Decay and Measurement Techniques
- Radiation Dose and Imaging
- Renal and Vascular Pathologies
- Voice and Speech Disorders
- Airway Management and Intubation Techniques
- Myasthenia Gravis and Thymoma
- Lymphoma Diagnosis and Treatment
Medical University of Lodz
2015-2025
Polish Mother’s Memorial Hospital Research Institute
2011-2021
Wojewódzki Szpital Specjalistyczny Nr 2
2004
Wojewódzki Szpital Zespolony
1996
The guidelines Thyroid Cancer 2022 are prepared based on previous Polish recommendations updated in 2018. They consider international - American Association (ATA) 2015 and National Comprehensive Network (NCCN); however, they adapted according to the ADAPTE process. strength of quality scientific evidence assessed GRADE system ATA NCCN recommendations. core changes made is inclusion results those studies that have already proven themselves prospectively. These extensions allow de-escalation...
The aim of the study was to evaluate functionality vocal folds (VF) by real-time, high-resolution ultrasonography (US) and correlate imaged features results laryngological examination (LE).The group comprised 50 patients (41 females nine males), qualified thyroidectomy. All had LE US before 2 days, months, 3 months after surgery. We used imaging identify VFs and, subsequently, a pulsed Doppler gate quantify tissue displacement velocity in vibrating VF section.LE revealed unilateral paralysis...
Significant advances have been made in thyroid cancer research recent years, therefore relevant clinical guidelines need to be updated. The current Polish "Diagnostics and Treatment of Thyroid Carcinoma" formulated at the "Thyroid Cancer Other Malignancies Endocrine Glands" conference held Wisła November 2015 [1].
Abstract Background Cardiac gamma cameras dedicated for myocardial perfusion imaging (MPI) perform studies faster and acquire higher quality images than traditional cameras. However, they are susceptible to some artifacts. We observed a previously unreported artifact, caused by residual radiopharmaceutical activity in injection site cubital fossa caught camera field of view. This study aims assess the impact these artifacts on image possibility their elimination. Study included 50 male...
Background: Since 1977 the susceptibility to SAT has been known be HLA-B*35-related in ~70% of patients. Recently it demonstrated that is associated with presence HLA-B*18:01 and DRB1*01, as well HLA-C*04:01. The association between type genetic background sonographic pattern disease never analyzed. aim study was evaluate potential correlation individual HLA haplotypes pattern, provide US characteristics analyzed cases. Methods: HLA-A, -B, -C, -DQB1, -DRB1 were genotyped using a...
Numerous scientific societies around the world have published their TIRADS (Thyroid Imaging Reporting and Data System) classifications that evaluate risk of malignancy focal thyroid lesions, presenting different ultrasound features for each category lesion size thresholds to determine eligibility biopsy. The use such estimation systems in lesions facilitates reporting findings improves qualification fine-needle aspiration biopsy (FNAB). In this publication, three most popular...
Computer-aided diagnosis (CAD) and other risk stratification systems may improve ultrasound image interpretation. This prospective study aimed to compare the diagnostic performance of CAD European Thyroid Imaging Reporting Data System (EU-TIRADS) classification applied by physicians with S-Detect 2 software based on Korean (K-TIRADS) combinations both methods (MODELs 1 5). In all, 133 nodules from 88 patients referred thyroidectomy available histopathology or unambiguous results cytology...
The standard management in patients with thyroid nodules is to assess the risk of malignancy, based on cytological examination. On other hand, there are patterns ultrasound (US) image, associated an increased malignancy. aim our study was create a diagnostic algorithm that would employ both data from US examination (expressed by total score, according scoring system) and FNAB results, classified Bethesda system (The System for Reporting Thyroid Cytopathology - TBSRTC categories).100 cancer...
To validate the European Thyroid Imaging and Reporting Data System EU-TIRADS classification in a multi-institutional database of thyroid nodules by analyzing obtained scores histopathology results.A total 842 lesions (613 benign, 229 malignant) were identified 428 patients (mean age 62.7 years) scored according to EU-TIRADS, using ultrasound examination. In all tumors, histopathological verification was performed.In 2 (154 nodules) benign; 3, only 3/93 malignancies identified. 4, 12/103...
Sclerostin, a product of SOST gene, is protein expressed by osteocytes that inhibits osteoblastic bone formation. Several hormones, including PTH and glucocorticosteroids, have been suggested to be possible regulators sclerostin production. The influence thyroid hormones on synthesis has not investigated, so far. aim the study was evaluate concentrations in patients before after treatment thyrotoxicosis.The involved 15 (4 men), mean age 51.8±15.3 years, BMI value - 24.7±3.5, with...
Iodine deficiency in pregnant women, even of a mild degree, may have adverse effects on both the mother and foetus. Despite obligatory model functioning iodine prophylaxis Poland, supply women during pregnancy physiological lactation is insufficient. Therefore, those groups should take additional supplementation at dose 150-200 μg/day. The aim this study was to examine effectiveness Poland.The assessment supply, urine concentration (UIC) spot sample, as well levels TSH, fT4, thyroid...
Background: Thyroid nodules with ultrasound (US) cancer risk features, and extra-thyroid lesions suggesting malignant lymph nodes, require prompt diagnosis, especially in children. The US pattern of intrathyroidal ectopic thymus (IET) can strongly suggest papillary thyroid carcinoma (PTC). thymic tissue (EET) mimic pathological nodes US. aim the study has been to demonstrate features diagnostic methods allowing finally confirm presence IET EET Material Methods: elastographic 16 (ET) were...
Aim: Evaluation of the diagnostic value first thyroglobulin (Tg) level measurement, performed after thyroidectomy, before another treatment, as an early marker either metastases or local recurrence differentiated thyroid carcinoma (DTC). Materials and methods: Data 178 patients (160 women, 18 men, 14-79 years) with DTC without known interference in Tg assay were evaluated retrospectively. In all patients, neck radioiodine uptake (Tup24), remnants volume (V), TSH measured. The Tg/V Tg/Tup24...
Sclerostin, a protein expressed by osteocytes, is negative regulator of bone formation. The aim the study was to investigate relationship between parathyroid hormone (PTH) and markers metabolism changes sclerostin concentrations before after treatment hyperthyroidism. Patients Methods . involved 33 patients (26 women), age (mean ± SD) 48 15 years, with Serum sclerostin, PTH, calcium, [osteocalcin (OC) collagen type I cross-linked C-telopeptide (CTX)] were measured at diagnosis...
Angiogenesis is a process of new blood vessel development from pre-existing vasculature. It crucial in normal physiology, as well several pathological conditions. The vascular endothelial growth factor (VEGF) represents family specific cell mitogens, involved angiogenesis and tumour development. aim the present study was to estimate influence L-thyroxine (L-T4) administration on poor-platelet plasma (P-PP) VEGF concentrations patients with induced short-term hypothyroidism, monitored for...
1. Youssef T, Mahdy Farid M, Latif AA. Thyroid surgery: Use of the LigaSure Vessel Sealing System versus conventional knot tying. Int J Surg. 2008; 6(4): 323–327. CrossRef Google Scholar
In 1997 a currently obligatory model of iodine prophylaxis, based on mandatory iodization household salt with 30 mg KI/kg, was introduced. The aim our study to assess the intake among school-age children living in Opoczno 3 subsequent time points - 1994, before establishment operating 1999 2 years after implementation prophylaxis and 2010, 14 its implementation.We assessed goitre incidence urine concentration (UIC) 104 207 174 2012. Age examined ranged from 6 15 years. thyroid volumes...
Recent reports suggested dendritic cells (DCs) to be important players in the pathogenesis of autoimmune thyroid processes humans. However, there are virtually no data addressing influence autoaggression-associated disturbances thyrometabolic conditions on DCs biology. The aim study was evaluate L-thyroxine supplementation conventional and plasmacytoid peripheral blood subtypes patients with hypothyroidism due Hashimoto's thyroiditis (HT). Eighteen newly diagnosed HT were included into...
Numerous TIRADS (Thyroid Image Reporting and Data System) classifications have been developed, various ultrasound (US) parameters are employed in different countries. The aim of our study was to introduce risk classification management a native population based on the Guidelines Polish National Societies Diagnostics Treatment Thyroid Carcinoma but with addition sonoelastography. Materials methods We examined prospectively 208 patients 305 thyroid lesions employing B-mode sonoelastography...
Aim: The aim of this study was to evaluate the inter- and intra-observer variability accuracy ultrasound assessment thyroid nodules using a descriptive lexicon. Materials methods: A prospective performed on complete examinations, including sonoelastography color Doppler 18 patients with 20 nodules. total records from these techniques were duplicated, numbered, randomly arranged. Five radiologists assessed recordings independently. Cohen Kappa Fleiss statistics used determine degree intra-...
Multiple cellular and humoral components of the immune system play a significant role in physiology pathophysiology various organs including thyroid. On other hand, both thyroid hormones thyroid-stimulating hormone (TSH) have been shown to exert immunoregulatory activities, which are difficult assess independently vivo . In our study we employed unique clinical model for assessment TSH biological function humans. The structure peripheral blood mononuclear cell populations was investigated,...