Little is known about the change of macular and peripapillary vessel density comparing to ganglion cell-inner plexiform layer (mGCIPL) thickness or retinal nerve fiber (pRNFL) in high myopic glaucoma longitudinal follow-up. A total 62 patients with myopia (71 eyes) were analyzed over an average follow-up 2.88 years, at least four optical coherence tomography angiography (OCTA) imaging sessions. Among participants, 47 eyes exhibited stable visual fields, while 24 showed progression. We...

We investigated the therapeutic effects and related mechanisms of algae oil (ALG) to protect retinal ganglion cells (RGCs) in a rat model anterior ischemic optic neuropathy (rAION).Rats were daily gavaged with ALG after rAION induction for seven days. The on evaluated using flash visual evoked potentials (FVEPs), retrograde labeling RGCs, TUNEL assay retina, ED1 staining nerves (ONs). levels inducible nitric oxide synthase (iNOS), IL-1β, TNF-α, Cl-caspase-3, ciliary neurotrophic factor...

Purpose: To investigate the diagnostic abilities of perfusion density (PD) and structural thickness parameters in peripapillary macular regions measured by optical coherence tomography angiography (OCTA) (OCT) to test if their early glaucoma are different between highly myopic (HM) non-highly (NHM) patients. Methods: A total 75 patients 65 controls were included analyses. The detection PD PD, along with ganglion cell-inner plexiform layer (mGCIPL) retinal nerve fiber (pRNFL) thicknesses...

Purpose: To describe the efficacy of laser and intravitreal injection anti-vascular endothelial growth factor (anti-VEGF) agents for patients with symptomatic retinal arterial macroaneurysm (RAM). Design: From 2009 to 2016, we collected exudative or hemorrhagic RAM all treated by focal photocoagulation. Methods: Nd:YAG was performed in subinternal limiting membrane (sub-ILM) hemorrhage. Intravitreal anti-VEGF were given eyes macular exudation as adjuncts. Changes visual acuity central foveal...

To investigate the accuracy of 6 intraocular lens (IOL) power calculation formulas in predicting refractive outcomes extremely long eyes.Department Ophthalmology, Far Eastern Memorial Hospital, Taiwan.Retrospective comparative study.In this retrospective single-center study, we reviewed 70 eyes patients with axial length (AL) ≥ 28 mm who had received an uneventful 2.2 corneal wound phacoemulsification and in-the-bag IOL placement. The actual postoperative results were compared to predicted...

As a continuing demand for booster shots against SARS-CoV-2, ocular adverse events following the coronavirus disease-2019 (COVID-19) vaccines can cause significant visual impairment, and they warrant high awareness detailed documentation of possible inflammatory manifestations. We present case series 11 patients presenting with manifestations relevant to vaccine-associated autoimmune response within 6 weeks after vaccination Oxford-AstraZeneca, Moderna, Pfizer-BioNTech at main tertiary...

Fifty-two eyes of 52 patients with treatment-naïve macular edema associated perfused branch retinal vein occlusion were retrospectively reviewed. Twenty-seven cases received PRN intravitreal bevacizumab, and 25 treated by aflibercept monthly follow-ups for 12 months. Both bevacizumab effective in reduction thickness improvement visual acuity the participants. antivascular endothelial growth factor agents had similar efficacy duration treatment these secondary to during a 12-month period. No...

Background and Objectives: Our study compared the visual anatomical outcomes of polypoidal choroidal vasculopathy (PCV) patients receiving intravitreal aflibercept (IVA) with or without photodynamic therapy (PDT) over 12 months. Materials Methods: This retrospective was performed for 60 eyes from treatment-naïve PCV. Thirty were treated using IVA monotherapy (IVA group), thirty a combination PDT (IVA/PDT group). The baseline characteristics, treatment outcomes, retreatment rates between two...

Abstract Cataract surgery leads to a sustained decrease in sitting intraocular pressure (IOP) patients with angle-closure glaucoma (ACG). The purpose of this study is evaluate whether cataract can also reduce postural IOP changes. We prospectively examined 106 eyes from 53 narrow angles scheduled for phacoemulsification. was measured the sitting, supine, and lateral decubitus positions using an ICare rebound tonometer before 1 week, month, 3 months postoperatively. mean baseline 17.9 ± 4.8...

Artificial intelligence has revolutionised smart medicine, resulting in enhanced medical care. This study presents an automated detector chip for age-related macular degeneration (AMD) using a support vector machine (SVM) and three-dimensional (3D) optical coherence tomography (OCT) volume. The aim is to assist ophthalmologists by reducing the time-consuming AMD examination. Using property of 3D OCT volume, modified feature connected method called slice-sum proposed, computational complexity...

Abstract The authors performed a retrospective and comparative study to compare the efficacy of intravitreal aflibercept bevacizumab for patients with myopic choroidal neovascularization (mCNV). treatment-naïve mCNV received 1 + PRN from March 2008 February 2013, while 2013 July 2016 were treated by aflibercept, all monthly follow-up 12 months. Primary outcome measures included change in central foveal thickness (CFT) mm spectral-domain optic coherence tomography, best corrected visual...

We report the case of a 70-year-old woman with history acute primary angle-closure glaucoma (PACG) in left eye who, 2 hours after fundus examination and mydriasis, experienced acutely elevated intraocular pressure (IOP) up to 40 mm Hg presence fully dilated pupil patent iridotomy. Gonioscopy revealed appositional angle closure 3 quadrants. After medical control IOP, sutureless cataract surgery was performed, including clear corneal incision, phacoemulsification, soft acrylic posterior...

Dexamethasone (DEX) implant has been shown to improve visual and anatomic function in patients with diabetic macular edema (DME). The purpose of this study was investigate the efficacy safety DEX between refractory naive eyes DME.We retrospectively reviewed data from pseudophakic center-involved DME who received (1 + as needed retreatment) May 2015 2017. Baseline clinical characteristics, changes best-corrected acuity (BCVA) central foveal thickness (CFT) were analyzed compared two groups....

We report a case of persistent pupillary membrane (PPM) associated with cataract managed by sequential argon-YAG laser membranectomy and phacoemulsification. A 30-year-old woman had an extensive PPM anterior capsular opacity the lens in right eye. Best corrected visual acuity (BCVA) was 20/60. Argon photocoagulation performed at junction iris collarette. Subsequently, neodymium:YAG used to sever strands PPM. These procedures resulted shrinkage without hemorrhage or other complications. The...

Abstract Macular retinal layer thickness asymmetry indices, particularly for the ganglion cell layer, are promising early indicators of glaucomatous damage. We evaluated macular perfusion density (MPDA) among normal, preperimetric glaucoma (PPG), and perimetric (PG) eyes, we tested performance MPDA in differentiating between control eyes with or without visual field (VF) defects. In this study, 116 (39 27 PPG, 50 PG eyes) optical coherence tomography angiography images macula were analysed....

Objective: We report the tri-center 1-year outcomes of a treat-and-extend (T&E) regimen in four-week intervals with ranibizumab for diabetic macular edema (DME). Methods: In this retrospective study, all eyes received 3 monthly loading injections 0.5 mg ranibizumab, followed by T&E DME. Regression models were used to evaluate associating factors visual and anatomical outcomes. Results: Ninety one from 64 patients enrolled. Mean LogMAR best-corrected acuity (BCVA) improved...