A5089831833- Sperm and Testicular Function
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Sexual Differentiation and Disorders
Zhejiang Wanli University
2022-2023
ABSTRACT KDM6B-mediated epigenetic modification of the testicular regulator Dmrt1 has previously been identified as primary switch male pathway in a temperature-dependent sex-determination (TSD) system; however, molecular network female not yet established. Here, we have functionally characterized for first time an upstream pathway, forkhead transcription factor FOXL2, Trachemys scripta, turtle species with TSD system. FOXL2 exhibited female-specific expression patterns before onset gonadal...
Abstract Estrogen signaling exerts a decisive role in female sex determination and differentiation chicken fish. Aromatase encoded by Cyp19a1 is the key enzyme that catalyzes conversion of androgen to estrogen. Correlative analyses implicate potential involvement aromatase reptilian sexual development, however, direct genetic evidence lacking. Herein, we found exhibited temperature-dependent sexually dimorphic expression, located medullary somatic cells early embryos red-eared slider turtle...