- Global Cancer Incidence and Screening
- Economic and Financial Impacts of Cancer
- Colorectal Cancer Screening and Detection
- Cancer Risks and Factors
- BRCA gene mutations in cancer
- Viral-associated cancers and disorders
- Endometrial and Cervical Cancer Treatments
- Genetic factors in colorectal cancer
- Polyomavirus and related diseases
- Childhood Cancer Survivors' Quality of Life
- Ovarian cancer diagnosis and treatment
- Acute Lymphoblastic Leukemia research
- Multiple and Secondary Primary Cancers
- Cervical Cancer and HPV Research
- Breast Cancer Treatment Studies
- Health Systems, Economic Evaluations, Quality of Life
- Adolescent and Pediatric Healthcare
- Lung Cancer Treatments and Mutations
- Microbial infections and disease research
- Gastric Cancer Management and Outcomes
- Healthcare Policy and Management
- Glioma Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Colorectal Cancer Treatments and Studies
- Hepatocellular Carcinoma Treatment and Prognosis
UC Davis Comprehensive Cancer Center
2019-2023
University of California, Davis
2013-2023
Veterinary Medical Teaching Hospital
2023
University of Missouri
2023
UC Davis Health System
2013-2021
London Cancer
2021
London School of Hygiene & Tropical Medicine
2020-2021
Cedars-Sinai Medical Center
2013-2020
University Hospitals of Derby and Burton NHS Foundation Trust
2019
Public Health Institute
2000-2016
BackgroundNational cancer incidence trends are presented for eight Asian American groups: Indians/Pakistanis, Chinese, Filipinos, Japanese, Kampucheans, Koreans, Laotians, and Vietnamese.
To identify characteristics associated with long-term survival for patients epithelial ovarian cancer using the California Cancer Registry.A descriptive analysis of all residents diagnosed between 1994 and 2001 was conducted identified through registry follow-up 2011. Characteristics who survived more than 10 years (long-term survivors) were compared three other cohorts: less 2 years, those at least but no 5 years.A total 3,582 out 11,541 (31%, confidence interval 30.2-31.8%) years. Younger...
Survival from metastatic cutaneous melanoma is substantially lower than for localized disease. Treatments have been limited, but remarkable clinical improvements reported in trials the last decade. We described characteristics of US patients diagnosed with during 2001-2013 and assessed trends short-term survival distant-stage disease.Trends 1-year net were estimated using Pohar Perme estimator, controlling background mortality life tables all-cause rates by county residence, single year age,...
BACKGROUND. Anal cancer is an uncommon malignancy in the US; up to 93% of anal cancers are associated with human papillomavirus. METHODS. Cases diagnosed between 1998 and 2003 from 39 population-based registries were analyzed. The following histologies included analysis: squamous cell, adenocarcinoma, small cell/neuroendocrine carcinomas. Incidence rates age-adjusted 2000 US standard population. RESULTS. From through 2003, annual invasive incidence rate was 1.5 per 100,000 persons. Squamous...
For breast cancer, guidelines direct the delivery of adjuvant systemic therapy on basis lymph node status, histology, tumor size, grade, and hormonal receptor status. We explored how race/ethnicity, insurance, census tract-level poverty education, hospital Commission Cancer (CoC) status were associated with receipt guideline-concordant therapy.Locoregional cancers diagnosed in 2004 (n = 6,734) from National Program Registries-funded seven-state Patterns Care study Centers for Disease Control...
BACKGROUND. Cancers of the colon and rectum are third most common malignancy among males females in United States, although incidence mortality have declined recent years. We evaluated trends colorectal cancer States by subsite stage at diagnosis. METHODS. Data for this analysis included all cases diagnosed between 1992 2001 reported to National Cancer Institute's Surveillance, Epidemiology, End Results (SEER) Program. Incidence rates were stratified gender, race/ethnicity, anatomic subsite,...
Abstract Background: Cancer is the leading cause of death among Hispanics. The burden cancer mortality within Hispanic groups has not been well quantified. Methods: rates for 2008–2012 in Florida were computed on basis race, ethnicity, and birthplace, specifically focusing major groups—Mexicans, Puerto Ricans, Cubans, Central Americans, South Dominicans. Age-adjusted rate ratios derived from negative binomial regression used to compare Hispanics, aggregated by group, nonHispanic whites...
Escalating costs and concerns about quality of cancer care have increased calls for measurement performance accountability providers health plans. The purpose the present cross-sectional study was to assess variability in by insurance type California.Persons with breast, ovary, endometrium, cervix, colon, lung, or gastric during period 2004 2014 were identified California Cancer Registry. Individuals stratified into 5 categories: private insurance, Medicare, Medicaid, dual Medicare Medicaid...
Abstract Background Transplant recipients have an elevated risk of cancer because immunosuppressive medications used to prevent organ rejection, but the authors’ knowledge no study date has comprehensively examined associations between transplantation status and mortality after a diagnosis. Methods The authors assessed cases in US general population (N=7,147,476) for 16 different types as ascertained from 11 registries. presence solid transplant prior diagnosis (N=11,416 cases) was...
Abstract Background: Through adequate screening and follow-up, cervical cancer can be prevented or detected at early-stage (stage I), which is related to excellent survival. Current guidelines recommend discontinuing for women ≥65 years with history of normal Pap and/or HPV tests, potentially leaving this age group vulnerable. This study examined late-stage disease in a population-based cohort. Methods: Using California Cancer Registry data, we identified 12,442 patients ages ≥21 first...
Patients with ovarian cancer often report having symptoms for months before diagnosis, but such findings are subject to recall bias. The aim of this study was provide an objective evaluation that precede a diagnosis cancer.Medicare provider claims linked records in the California Surveillance, Epidemiology, and End Results data base were utilized extract procedure codes 1985 women age 68 years or older who resided cancer, 6024 elderly localized breast 10,941 age-matched, Medicare-enrolled...
Very few studies have simultaneously examined incidence of the leading cancers in relation to socioeconomic status (SES) and race/ethnicity populations including Hispanics Asians. This study aims describe SES disparity cancer within each four major racial/ethnic groups (non-Hispanic white, black, Hispanic, Asian/Pacific Islander) for five sites, female breast cancer, colorectal cervical lung prostate cancer.Invasive sites diagnosed from 1998 2002 (n = 376,158) California were included study....
Liver cancer is highly fatal and the most rapidly increasing in US, where chronic hepatitis C (HCV) infection leading etiology. HCV particularly prevalent among 1945-1965 birth cohort, so-called "baby boomers". Focusing on this cohort-etiology link, we aim to characterize liver patterns for 15 unique US populations: White, African American, Mexican Immigrant, Cuban Chinese, others.Individual-level mortality data from 2012-2016 health departments of 3 large states - California, Florida, New...
A small percentage of bladder cancers in the general population have been found to harbor DNA viruses. In contrast, up 25% tumors solid organ transplant recipients, who are at an increased risk developing cancer and overall poorer outcomes, BK polyomavirus (BKPyV). To better understand biology mechanisms carcinogenesis from potential oncoviruses, we performed whole genome transcriptome sequencing on specimens 43 patients. Nearly half this patient contained viral sequences. The most common...
Abstract Background Uninsured adolescents and young adults (AYAs) those with publicly funded health insurance are more likely to be diagnosed cancer at later stages. However, prior population-based studies have not distinguished between AYAs who were continuously uninsured from gained Medicaid coverage the time of diagnosis. Methods AYA patients (ages 15–39 years) nine common cancers 2005 2014 identified using California Cancer Registry data. This cohort was linked enrollment files determine...
Asian American and Native Hawaiian/Pacific Islanders (AANHPI) are the fastest growing minority in United States. Cancer is leading cause of death for AANHPIs, despite relatively lower cancer morbidity mortality. Their recent demographic growth facilitates a detailed identification AANHPI populations with higher risk.
OBJECTIVES: The purpose of this study was to determine temporal trends in breast-conserving surgery California from 1988 through 1995. METHODS: Logistic regression used analyze data on 104,466 cases early-stage breast cancer reported the Cancer Registry. RESULTS: A monotonically increasing trend detected after adjustment for age, race/ethnicity, stage at diagnosis, and neighborhood education level. Breast-conserving increased similar rates among all racial/ethnic groups. Older Asian or...
Abstract BACKGROUND: Interactions with comorbidity burden and comorbidity‐related care have not been examined as potential explanations for racial/ethnic disparities in advanced‐stage breast cancer at diagnosis. METHODS: The authors used linked Surveillance, Epidemiology, End Results‐Medicare data to determine whether are associated stage diagnosis, these associations mediated by mammography use, they explain disparities. Stage diagnosis use were analyzed multivariate regression models,...
Lack of annual population estimates for disaggregated Native Hawaiian and Other Pacific Islander (NHOPI) populations limits the ability to examine cancer incidence rates trends understand burdens among NHOPIs.Utilizing 1990 2000 census data, we estimated by age sex Hawaiians, Samoans, Guamanians/Chamorros 1990-2008 in regions covered 13 National Cancer Institute's SEER registries. diagnoses during from these registries were used calculate age-adjusted (2000 US Standard) sex, calendar...
Background Solid organ transplant recipients have an elevated risk of cancer. Quantifying deaths attributable to cancer can inform priorities reduce burden. Methods Linked transplantation and registry data were used identify incident cancers among solid in the United States (1987‐2014). Population‐attributable fractions (PAFs) due corresponding cancer‐attributable mortality rates estimated using Cox models. Results Among 221,962 recipients, 15,012 developed Approximately 13% (PAF, 13.2%)...
The presence of comorbid medical conditions can significantly affect a cancer patient's treatment options, quality life, and survival. However, these important data are often lacking from population-based registries. Leveraging routine linkage to hospital discharge data, comorbidity score was calculated for patients in the California Cancer Registry (CCR) database.California cases diagnosed between 1991 2013 were linked statewide data. A Deyo Romano adapted Charlson Comorbidity Index each...