A5033392544- Renal cell carcinoma treatment
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Renal and related cancers
- Cutaneous lymphoproliferative disorders research
- Bladder and Urothelial Cancer Treatments
- Radiomics and Machine Learning in Medical Imaging
- Autoimmune Bullous Skin Diseases
- Full-Duplex Wireless Communications
- Polyomavirus and related diseases
- Multiple and Secondary Primary Cancers
- Reproductive Biology and Fertility
- Genetic Associations and Epidemiology
- Economic and Financial Impacts of Cancer
- Antenna Design and Analysis
- Cancer and Skin Lesions
- MRI in cancer diagnosis
- Cancer Genomics and Diagnostics
- Urologic and reproductive health conditions
- Virtual Reality Applications and Impacts
- Renal and Vascular Pathologies
- DNA Repair Mechanisms
- Psoriasis: Treatment and Pathogenesis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Nonmelanoma Skin Cancer Studies
University of Maryland, Baltimore
2021-2025
John H. Stroger, Jr. Hospital of Cook County
2020-2024
West Virginia University
2024
Western University of Health Sciences
2024
University of California, Los Angeles
2019-2023
Molecular Theranostics (United States)
2022
VA Palo Alto Health Care System
2021
Stanford University
2021
Palo Alto University
2021
Salford Royal NHS Foundation Trust
2021
DNA double-strand break repair by homologous recombination entails the resection of ends to reveal ssDNA tails, which are used invade a template. CtIP and its yeast ortholog Sae2 regulate nuclease activity MRE11 in initial stage resection. Deletion mouse or SAE2 engenders more severe phenotype than inactivation, indicative broader role CtIP/Sae2. Here, we provide biochemical evidence that promotes long-range via BLM-DNA2 pathway. Specifically, interacts with BLM enhances helicase activity,...
We demonstrate the effects of a new quantitative trait locus (QTL), designated pln3, that was mapped in backcross population derived from strains bees selected for amount pollen they store combs. independently confirmed pln3 by demonstrating its on individual foraging behavior, as we did previously QTLs pln1 and pln2 (Hunt et al. 1995). QTL is very robust behavior. In this study, again shown to affect behavior workers hybrid strains. addition, stored combs colonies wide cross European...
BACKGROUND Panel testing has been recently introduced to evaluate hereditary cancer; however, limited information is available regarding its use in kidney cancer. METHODS The authors retrospectively reviewed test results and clinical data from patients who underwent targeted multigene panel of up 19 genes associated with cancer 2013 2016. frequency positive (mutation/variant likely pathogenic), inconclusive (variant unknown significance), negative was evaluated. A logistic regression...
In this work we present an inexpensive method of exploring a large immersive virtual environment (VE). More specifically, describe physically leaning to explore VE on Nintendo Wii Fit Balance Board, Wii-Leaning. two experiments described in paper, directly compare our Wii-Leaning other methods VE. Experiment 1, the feasibility and accuracy is tested by comparing it joystick navigation. spatial orientation task, find that when participants their representation more accurate. 2, then "walking...
Cervical cancer (CC) disproportionately affects minorities who have higher incidence and mortality rates. Standard of care for locally advanced CC involves a multimodality approach including brachytherapy (BT), which independently improves oncologic outcomes. Here, we examine the impact insurance status race on BT utilization with SEER database.In total, 7,266 patients stage I-IV diagnosed from 2007 to 2015 were included. utilization, overall survival (OS), disease-specific (DSS)...
Introduction: Accurate prediction of the risk ischemic stroke (IS) is vital for prevention and would be aided by multimodal biomarkers integrating genetic, clinical, functional data. The role imaging EKG based atrial measurements, other than fibrillation (AF), in IS uncertain many strokes remain cryptogenic despite extensive work-up. As an exploratory step to improve evaluation including traits, we developed a novel deep learning model demographic clinical variables with phenotypic genotypic...
Introduction: Atrial cardiomyopathy (AC) is associated with ischemic stroke (IS) in the absence of known atrial fibrillation (AF), but it not if AC causally linked to IS. We are using Mendelian randomization (MR) study whether traits Methods: used genetic variants by GWAS as proxies for defined cardiac MRI (left (LA) minimum and maximum volumes active, passive total emptying fractions (LAAEF, LAPEF, LATEF)) EKG (PQ interval). Linkage these IS TOAST subtypes was studied cases controls from...
Abstract DNA double-strand break repair by homologous recombination begins with nucleolytic resection of the 5’ strand at ends. Long-range is catalyzed EXO1 and BLM-DNA2, which likely have to navigate through ribonucleotides damaged bases. Here, we show that a short stretch terminus stimulates EXO1. Ribonucleotides within flap are resistant cleavage DNA2, extended RNA:DNA hybrids inhibit both separation BLM Moreover, 8-oxo-guanine impedes but enhances an apurinic/apyrimidinic site BLM-DNA2...
In this work, we present a simple method of "walking in place" (WIP) using the Microsoft Kinect to explore virtual environment (VE) with head-mounted display (HMD). Other studies have shown that WIP VE is equivalent normal walking terms spatial orientation. This suggests promising way large VE. The sensor great tool for implementing because it enables real time skeletal tracking and relatively inexpensive (110 USD). However, information obtained from sensors can be noisy. Thus, research...