- Photoacoustic and Ultrasonic Imaging
- Photodynamic Therapy Research Studies
- Optical Coherence Tomography Applications
- Optical Imaging and Spectroscopy Techniques
- Ultrasound Imaging and Elastography
- Nanoplatforms for cancer theranostics
- Advanced Fiber Optic Sensors
- Advanced Fiber Laser Technologies
- Photonic and Optical Devices
- Quantum optics and atomic interactions
- Innovative Energy Harvesting Technologies
- Photonic Crystal and Fiber Optics
- Nonlinear Optical Materials Studies
- Energy Harvesting in Wireless Networks
- Optical Network Technologies
- Advanced Radiotherapy Techniques
- Digital Holography and Microscopy
- Wireless Power Transfer Systems
- Cellular Mechanics and Interactions
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Diagnosis and Treatment
- Geoscience and Mining Technology
- Photorefractive and Nonlinear Optics
- Hydraulic Fracturing and Reservoir Analysis
- Reservoir Engineering and Simulation Methods
Guangdong Provincial Hospital of Traditional Chinese Medicine
2015-2025
Guangzhou University of Chinese Medicine
2025
Shandong Academy of Agricultural Sciences
2025
Institute of Plant Protection
2025
China Jiliang University
2024
Guangxi University
2023
Chang'an University
2022
Northeastern University
2019-2021
State Key Laboratory of Synthetical Automation for Process Industries
2019-2021
Syracuse University
2021
Dynamic optical coherence elastography is used to determine in vivo skin biomechanical properties based on mechanical surface wave propagation. Quantitative Young's moduli are measured human from different sites, orientations, and frequencies. Skin thicknesses, including measurements layers, also simultaneously. Experimental results show significant differences among between directions parallel orthogonal Langer's lines, under hydration states. Results suggest waves with driving frequencies...
Surface plasmon resonance (SPR) optical fiber biosensors can be used as a cost-effective and relatively simple-to-implement alternative to well established bulky prism configurations for high sensitivity biological sample measurements. The miniaturized size remote operation ability offer them multitude of opportunities single-point sensing in hard-to-reach spaces, even possibly vivo. biosensor configuration reported this work uses tilted Bragg grating (TFBG) commercial single mode coated...
We present the first three-dimensional (3D) data sets recorded using optical coherence elastography (OCE). Uni-axial strain rate was measured on human skin in vivo a spectral-domain tomography (OCT) system providing >450 times higher line than previously reported for OCE imaging. Mechanical excitation applied at frequency of 125 Hz ring actuator sample arm with, time measurements, controlled static preload. performed 3D-OCE, processed 2D and displayed 3D, normal hydrated observed more...
As the realm of smart wearable electronic devices undergoes continuous evolution, tapping into energy generated by everyday human movement presents a compelling alternative to conventional batteries for powering these devices. However, harvesting face limitations in capturing from ultra-low frequency mechanical excitation. This paper proposes novel dual piezoelectric-electromagnetic harvester (DHEH). The DHEH consists two PZTs comprising piezoelectric unit (PEH), arc-shaped driving magnets,...
Mechanical forces such as adhesion, shear stress and compression play crucial roles in tissue growth, patterning development. To understand the role of these mechanical stimuli, it is great importance to measure biomechanical properties developing, engineered, natural tissues. enable measurements on micro-scale, a novel, dynamic, non-invasive, high-speed optical coherence elastography (OCE) system has been developed utilizing spectral-domain tomography (OCT) wave driver. Experimental results...
The availability of a real-time non-destructive modality to interrogate the mechanical properties viscoelastic materials would facilitate many new investigations. We introduce optical method for measuring elastic samples which employs magnetite nanoparticles as perturbative agents. Magnetic distributed in silicone-based are displaced upon probing with small external magnetic field gradient and depth-resolved coherence phase shifts allow tracking scatterers sample nanometer-scale sensitivity....
We present an optical technique to image the frequency-dependent complex mechanical response of a viscoelastic sample. Three-dimensional hyperspectral data, comprising two-dimensional B-mode images and third dimension corresponding vibration frequency, were acquired from samples undergoing external excitation in audio-frequency range. describe coherence tomography (OCT) signal when is applied sample detail processing acquisition techniques used extract local three-dimensional data that, due...
A strain sensor based on cascaded Sagnac loops with two polarization-maintaining photonic crystal fibers (PMPCFs) has been experimentally demonstrated. Air holes distributed the cross section of PMPCF go through whole fiber, which makes special fiber more sensitive to ambient force compared conventional optical fiber. The lengths PMPCFs are close, but not same, form envelopes total output spectrum and then obtain high resolution detected parameter by Vernier effect. influences difference in...
A dynamic spectral-domain optical coherence elastography (OCE) imaging technique is reported. In this technique, audio-frequency compressive vibrations are generated by a piezoelectric stack as external excitation, and strain rates in the sample calculated mapped quantitatively using phase-sensitive tomography. At different driving frequencies, provides contrast between regions with mechanical properties, thus used to mechanically characterize tissue. We present images of three-layer...
Acoustomotive optical coherence elastography (AM-OCE), a dynamic and internal excitation technique, is reported. Acoustic radiation force was used for mechanical excitation, spectral-domain tomography detection. Mechanical properties of gelatin tissue phantoms were measured by AM-OCE verified using rheometry results. Measured including shear moduli damping parameters the samples double when their polymer concentration increases from 3% to 4%. Spectral analysis also performed on acquired...
Dosimetry of singlet oxygen (1O2) is particular interest because it the major cytotoxic agent causing biological effects for type-II photosensitizers during photodynamic therapy (PDT). An in-vivo model to determine threshold dose, [1O2]rx,sh, PDT was developed.An radiation-induced fibrosarcoma (RIF) tumor mouse used correlate radius necrosis calculation based on explicit dosimetry light fluence distribution, tissue optical properties, and photosensitizer concentrations. Inputs include five...
Aquaporin-2 (AQP2) has been identified as one of the most important biomarkers for nephrotic syndrome analysis. Here we propose and experimentally demonstrate a surface Plasmon resonance (SPR) reflective fiber-based biosensor label-free specific detection urinary AQP2 with high resolution. The utilizes tilted fiber Bragg grating 50 nm gold coating to excite SPR refractive indices change at surroundings. sensor works very controllable cross-sensitivities because core mode is temperature...
ABSTRACT Double cropping in cotton fields is a prominent agricultural practice the Yellow River basin, enhancing yields and overall production benefits. However, there limited research on agronomic performance long‐term ecological sustainability of cotton‐based systems. This study evaluates service functions various systems, focusing crop productivity security. Field experiments were conducted to examine dynamics insect pest natural enemy populations, soil nutrients, investment, economic...
We employed the scattering-phase theorem recently derived in our laboratory to extract tissue scattering properties from quantitative phase images. Using path-length maps that contain nanoscale information about tissue, mean free path l(s) and anisotropy factor g were measured a spatially resolved manner.
Macroscopic modeling of singlet oxygen (1O2) is particular interest because it the major cytotoxic agent causing biological effects for type II photosensitizers during PDT. We have developed a macroscopic model to calculate reacted concentration ([1O2]rx An in-vivo RIF tumor mouse used correlate necrosis depth calculation based on explicit PDT dosimetry light fluence distribution, tissue optical properties, and photosensitizer concentrations. Inputs include 4 specific photochemical...
A high-power low-noise fiber Brillouin amplifier (FBA) has been demonstrated for slow-light delay buffer. Its features including gain, gain saturation, and noise figure (NF), have characterized. Among them, the saturation is highlighted because it a fundamental limitation FBA-based It testified that more easily achieved lower signal-to-pump ratio (SPR), NF reduced at higher pump level when below threshold. The experiment up to 20-ns enhancement could be obtained in this FBA -30-dBm input...
In this research, a novel amphiphilic hydrophobically associative polymer nanocomposite (ADOS/OMMT) was prepared using acrylamide (AM), sodium 4-vinylbenzenesulfonate (SSS), N, N′-dimethyl octadeyl allyl ammonium bromide (DOAAB) and organo-modified montmorillonite (OMMT) through in situ polymerization. Both X-ray diffraction patterns transmission electron microscopy images verified the dispersion morphology of OMMT copolymer matrix. Then, effect introduction layers on properties studied by...