- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Intracranial Aneurysms: Treatment and Complications
- Cardiac Arrhythmias and Treatments
- Prostate Cancer Treatment and Research
- Atrial Fibrillation Management and Outcomes
- Hormonal and reproductive studies
- Inflammatory Biomarkers in Disease Prognosis
- Nerve Injury and Rehabilitation
- Spinal Fractures and Fixation Techniques
- Infectious Encephalopathies and Encephalitis
- Neurological disorders and treatments
- Estrogen and related hormone effects
- Botulinum Toxin and Related Neurological Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Neurosurgical Procedures and Complications
- Ophthalmology and Eye Disorders
- Peripheral Nerve Disorders
- Cerebral Venous Sinus Thrombosis
- Pharmacological Effects of Medicinal Plants
- Neurological Disorders and Treatments
- Cerebrospinal fluid and hydrocephalus
- Spinal Cord Injury Research
Hospital Israelita Albert Einstein
2023-2025
Irmandade da Santa Casa de Misericórdia de São Paulo
2018-2024
Faculdade de Ciências Médicas da Santa Casa de São Paulo
2014-2024
Hospital Samaritano de São Paulo
2023
Universidade Federal de São Paulo
2016-2020
Hospital São Paulo
2020
University of Bari Aldo Moro
2017
Federico II University Hospital
2003
Background and Purpose— Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in elderly. We undertook an international survey to characterize frequency AF-associated stroke, methods AF detection, patient features. Methods— Consecutive patients hospitalized for 2013 2014 were surveyed from 19 research centers different countries. Data analyzed by global regions World Bank income levels. Results— Of 2144 with 590 (28%; 95%...
Background: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor symptoms like bradykinesia, tremor, rigidity, and postural instability. Additionally, PD severely impacts physical abilities independence. Chronic pain, affecting 67.6% of patients, varies in form presentation, it often underdiagnosed. Objectives: This study investigated the association between chronic pain symptom severity patients. Methods: analysis used data from cross-sectional on 52 patients...
SUMMARY Orchiectomy is often used in the management of metastatic adenocarcinoma prostate, an androgen dependent tumour, since it markedly reduces concentrations plasma testosterone (to a mean level 28 ± 16 (SD) ng/100 ml) and temporarily inhibits growth neoplasma. In some orchiectomized patients, however, values androstenedione do not drop to these levels, but remain higher, around 137 23 ml 213 39 respectively. treatment with dexamethasone significantly decreased levels 22 20 ( P...
Purpose To describe the long-term efficacy and side effects of treatment blepharospasm with botulinum neurotoxin type A (Botox). Methods total 178 patients were treated by injections toxin in Eye Clinic University Naples from 1980 to 2001. The severity spasm for each patient was graded on a four-point scale. Duration improvement assessed reported months. Results Of cases, 10 lost follow-up; remaining patients, 93% after treatments. mean duration 3.6 Twelve (76%) who underwent more than 14...
Cerebrovascular disease is one of the most important causes death and disability worldwide. The patient's inability to identify warning signs stroke substantially delays search for emergency services, which related directly a worse outcome. Thus, during 2011 Stroke Campaign in Brazil, survey was conducted lay population's knowledge with regard recognition, treatment, prevention stroke.This retrospective, cross-sectional, multicenter study held cities throughout southeastern Brazil.The...
ABSTRACT Intracerebral hemorrhage (ICH), defined as bleeding into the brain parenchyma, is a significant public health issue. Although it accounts for only 10 to 15% of strokes, associated with highest morbidity and mortality rates. Despite advances in field stroke neurocritical care, principles acute management have fundamentally remained same over many years. The main treatment strategies include aggressive blood pressure control, early hemostasis, reversal coagulopathies, clot evacuation...
ABSTRACT Cervical arterial dissection accounts for only a small proportion of ischemic stroke but arouses scientific interest due to its wide clinical variability. Objective: This study aimed evaluate risk factors, outline characteristics, compare treatment with antiaggregation or anticoagulation, and explore the prognosis patients cervical dissection. Methods: An observational, retrospective using data from medical records on between January 2010 August 2015. Results: The total number was...
Stroke is a major cause of disability worldwide and neurological emergency. Intravenous thrombolysis mechanical thrombectomy are effective in the reperfusion parenchyma distress, but impossibility to determine exact time onset was an important exclusion from treatment until few years ago.To review clinical radiological profile patients with unknown-onset stroke, imaging methods guide treatment, suggest protocol for therapeutic approach.The different were grouped according current...
Cerca de 20 a 30% dos acidentes vasculares cerebrais (AVC) são origem cardioembólica, sendo fibrilação atrial (FA) principal causa cardiogênica. A FA é uma situação não rara na população e aumenta sua prevalência com idade. Está relacionada quadros AVC mais graves, comparativamente às demais causas. prevenção em pacientes deve ser realizada anticoagulação oral, varfarina medicação utilizada; no entanto, esta difícil controle, devido múltiplas interações medicamentosas, interações...
Quantify the NLR in ischemic stroke patients first 72 hours and investigate possible correlation between values, risk factors its severity, according to National Institutes of Health Stroke Scale (NIHSS).
: Studies suggest that the neutrophil/lymphocyte ratio (NLR) may be a prognostic marker for different diseases with inflammatory components. This study aimed to quantify NLR in individuals affected by subtypes and severities of ischemic stroke associated it risk factors treatment, compared results data from healthy individuals.
ABSTRACT Stroke is currently the second leading cause of death in Brazil. Neurologists’ reports on absence adequate resources for stroke care are frequent; however, there no objective data this perception. Objective To assess perception neurologists conditions Methods Neurologists from all over Brazil were surveyed by means an anonymous questionnaire about main shortcomings care, focusing particularly physical structure and infrastructure (diagnostic methods, patient transport, availability...
Approximately 20-30 % of strokes are cardioembolic, and atrial fibrillation (AF) is the main cardiogenic cause. AF not an uncommon issue in population, its prevalence increases with age related to a more severe stroke. The prevention stroke patients should be performed oral anticoagulation, warfarin most frequently used medication; however, this medication difficult managed due multiple drug interactions dietary interactions, which demands periodical laboratory monitoring. Half who started...
Diffuse large B-cell lymphoma (DLBCL), the most common type of non-Hodgkin lymphoma, is recognized as a heterogeneous disease with distinct molecular subtypes derived from different stages differentiation. The contribution tumor microenvironment to pathogenesis and survival DLBCL poorly understood. However, several recent studies have yielded intriguing findings shed some light on possible roles microenvironment. In this retrospective study, data 29 patients diagnosed between 2009 2013 were...
O acidente vascular cerebral (AVC) é uma doença de grande importância médica e social, devido a sua elevada prevalência, morbidade mortalidade1. Portanto, todo conhecimento seu respeito merece destaque. Tem--se observado um significativo avanço no tratamento nos cuidados específicos o que fez com as taxas mortalidade tenham sido reduzidas, porém infelizmente estas conquistas não se acompanham quanto à prevenção, vez incidência tem acompanhado índices semelhantes queda2-4. As mortalidade,...
The NIH Stroke Scale (NIHSS) is widely adopted in clinical practice. Despite being originally designed for research use, the NIHSS a valued resource communication and prognostication, it useful decision-making process regarding reperfusion therapies prophylaxis. However, its assessment can be laborious complex among even certified healthcare providers. In context of increasing telemedicine an accurate may crucial acute stroke management We aimed to create validate automated tool (SPOKES)...
Stroke is the second leading cause of death and primary disability in Brazil. Ischemia resulting from a stroke triggers an inflammatory response central nervous system, primarily mediated by neutrophils, lymphocytes, macrophages. Recent research suggests that neutrophil/lymphocyte ratio (NLR) peripheral blood can serve as reliable marker systemic inflammation various diseases. The present study aims to quantify NLR patients diagnosed with ischemic stroke, who received treatment at...
Introduction: Pain is a significant, multifactorial problem worldwide. Curcumin, derivative of the rhizome turmeric (Curcuma longa), has been historically used in Asian medicine due to its anti-inflammatory and analgesic properties. Recent clinical trials have demonstrated potential effect. This mini-review aimed summarize effect curcumin literature. Methods: The Medline (PubMed) Cochrane Central Register Controlled Trials databases were searched for articles published until Sep 15th, 2022....