A5068391462- Mycobacterium research and diagnosis
- Dermatological diseases and infestations
- Parasitic Diseases Research and Treatment
- Humic Substances and Bio-Organic Studies
- Syphilis Diagnosis and Treatment
- Infectious Diseases and Mycology
- Parasites and Host Interactions
- Zoonotic diseases and public health
- Child Nutrition and Water Access
- Mosquito-borne diseases and control
- Virology and Viral Diseases
- Tuberculosis Research and Epidemiology
- Parasite Biology and Host Interactions
- Infectious Diseases and Tuberculosis
- Maternal Mental Health During Pregnancy and Postpartum
- Trypanosoma species research and implications
- Interprofessional Education and Collaboration
- Health Systems, Economic Evaluations, Quality of Life
- SARS-CoV-2 detection and testing
- Global Maternal and Child Health
- Biosensors and Analytical Detection
- Cultural Competency in Health Care
- Fungal Infections and Studies
- Bipolar Disorder and Treatment
- Wound Healing and Treatments
Kumasi Centre for Collaborative Research in Tropical Medicine
2020-2025
Kwame Nkrumah University of Science and Technology
2020-2025
Kwame Nkrumah University
2024
Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting can help improve management Buruli ulcer. We examine three methods for determination RoH their use as predictors
Background Stigma related to skin neglected tropical diseases like Buruli ulcer (BU) and yaws has remained underexplored existing studies are limited individual despite the WHO call for integration in disease management. Within two districts central Ghana, we explored stigma associated with BU understand overlaps disease-specific nuances help guide integrated interventions. Methodology/Principal findings In-depth interviews were conducted 31 current or formerly affected individuals assess...
Integrated strategies are recommended to tackle neglected tropical diseases of the skin (skin NTDs), which pose a substantial health and economic burden in many countries, including Ghana. We describe development an integrated decentralised strategy designed improve experiences NTDs Atwima Mponua district Ashanti Region. A multidisciplinary research team led iterative process develop overall specific interventions, based on theory change informed by formative conducted district. The involved...
In this study, we report on findings from approaches used, the outcomes and lessons learnt laboratory support provided for integrated control of skin NTDs including Buruli ulcer (BU), yaws in seven selected districts Ghana. Actions implemented July 2018 to October 2022 included; training district-level health workers specimen collection, storage, transport laboratories, case searches, continual monitoring supervision trained workers, confirmation BU samples providing results analysed guide...
Integrated approaches to managing co-endemic neglected tropical diseases (NTDs) of the skin within primary healthcare services are complex and require tailoring local contexts. We describe formative research in Atwima Mponua District Ghana’s Ashanti Region designed inform development a sustainable intervention improve access NTD care. employed convergent, parallel, mixed-methods design, collecting data from February 2021 2022. quantitatively assessed service readiness using standardised...
Previous studies have demonstrated secondary microbial infection of Buruli ulcer (BUD) lesions before, during and after treatment. However, there is limited data on the bacterial diversity across treatment their influence clinical outcome. The present study aimed to investigate relationship between within BUD outcome in affected individuals.
Yaws is a skin debilitating disease caused by Treponema pallidum subspecies pertenue with most cases reported in children. World Health Organization (WHO) aims at total eradication of this through mass treatment suspected followed an intensive follow-up program. However, effective diagnosis pivotal the successful implementation control Recombinase polymerase amplification (RPA), isothermal nucleic acid technique offers wider range differentiation pathogens including those isolated from...
The COVID-19 pandemic led to severe health systems collapse, as well logistics and supply delivery shortages across sectors. Delivery of PCR related healthcare supplies continue be hindered. There is the need for a rapid accessible SARS-CoV-2 molecular detection method in low resource settings.
Community Based Surveillance Volunteers (CBSVs) have been instrumental in the management of Neglected Tropical Diseases (NTDs) but a concern that their services scale up programmes may be affected due to high attrition rates has widely acknowledged. We explored roles and capacity needs existing CBSVs inform for successful integrated NTD programme Ghana similar contexts.We conducted qualitative interviews with 50 CBSVs, 21 Nurses, 4 Disease control officers, 7 skin researchers, 2 patients...
The extent to which neuropsychiatric sequelae affects the mental health status and quality of life former gambiense human African trypanosomiasis (gHAT) patients is not known.We assessed anxiety, depression health-related (HRQoL) in 93 their age- sex-matched controls using Hospital Anxiety Depression Scale, Becks Inventory 36-item Short Form Health Survey structured interviews Vanga zone Democratic Republic Congo. Data were analysed Stata version 14.0. degree association between neurologic...
Yaws is a skin debilitating disease caused by Treponema pallidum subspecies pertenue with most cases reported in children. World Health Organization (WHO) aims at total eradication of this through mass treatment suspected followed an intensive follow-up program. However, effective diagnosis pivotal the successful implementation control Recombinase polymerase amplification (RPA), isothermal nucleic acid technique offers wider range differentiation pathogens including those isolated from...
Background: According to the WHO, neglected tropical diseases (NTDs) affect over 2 billion people worldwide. While links between nutrition and many have become clear recent decade, NTDs lagged behind linkage with is largely unknown. We conducted this systematic review meta-analysis determine current status of research on role diet in pathogenesis NTDs. Methodology: PubMed, Embase, Scopus African Journal online databases were searched using predefined search terms. included all original...
Abstract Introduction Skin diseases such as impetigo pose a significant public health challenge in low resource settings. Despite this, there is dearth of epidemiological data on the prevalence this condition Ghana. Methods We conducted cross sectional study three settings Ghana: community members East Mamprusi district North region, secondary school Sekyere district, and inmates Kumasi central prisons both Ashanti region. Following period training, we performed standardised skin examination...
Background There is a dearth of information concerning the epidemiology human scabies in prisons. Therefore, we aimed to assess burden and ascertain if prevalence was high enough warrant mass drug administration (MDA) with ivermectin medium security prison central Ghana. Methods We conducted cross-sectional study December 2022 recruited inmates at Kumasi Medical history demographic collected using REDCap questionnaire. A standardised skin examination exposed regions body performed on all...
Buruli ulcer (BU) can lead to disfiguring ulcers and permanent disability. The 2030 World Health Organization (WHO) road map for Neglected Tropical Diseases (NTDs) calls major scaling up in diagnosis management eliminate disability due the disease. Current treatment BU is with daily oral rifampicin (10mg/kg dose) clarithromycin (15mg/kg eight weeks, combined standard gauze wound dressings. Dialkylcarbamoyl chloride (DACC)-coated dressings have been shown irreversibly bind bacteria on...
<ns4:p><ns4:bold>Background</ns4:bold>: Buruli ulcer (BU) can lead to disfiguring ulcers and permanent disability. The 2030 World Health Organization (WHO) road map for Neglected Tropical Diseases (NTDs) calls major scaling up in diagnosis management eliminate disability due the disease. Current treatment BU is with daily oral rifampicin (10mg/kg dose) clarithromycin (15mg/kg eight weeks, combined standard gauze wound dressings. Dialkylcarbamoyl chloride (DACC)-coated dressings have been...
<h3>Background</h3> Previous studies have demonstrated secondary microbial infection of Buruli ulcer (BU) lesions before, during and after treatment. However, there is limited data on the resistance profile these organisms their influence development paradoxical reactions. The present study aimed to investigate microbiome in BU therapy at onset a reaction (PR). <h3>Methods</h3> We investigated bacteria diversity patients with PCR confirmed from 5 endemic districts within central Ghana....