A5045032593- Fermentation and Sensory Analysis
- Horticultural and Viticultural Research
- Cannabis and Cannabinoid Research
- Phytochemicals and Antioxidant Activities
- Biochemical and biochemical processes
- Spectroscopy Techniques in Biomedical and Chemical Research
- Forensic Toxicology and Drug Analysis
- Pesticide Residue Analysis and Safety
- Mass Spectrometry Techniques and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Essential Oils and Antimicrobial Activity
- Botanical Research and Chemistry
- Petroleum Processing and Analysis
- Hepatitis C virus research
- Plant biochemistry and biosynthesis
- Hydrocarbon exploration and reservoir analysis
- Analytical Chemistry and Chromatography
- GABA and Rice Research
- Protein purification and stability
- Insect and Pesticide Research
- Analytical chemistry methods development
- Advanced Chemical Sensor Technologies
- Coffee research and impacts
- Free Radicals and Antioxidants
- Bee Products Chemical Analysis
University of British Columbia
2017-2022
Spinal Cord Injury BC
2021
Okanagan University College
2018-2021
Box (United States)
2016
Flex (Canada)
2016
Cochrane
2013
Amgen (United States)
2009
University of Ottawa
2006-2007
Steacie Institute for Molecular Sciences
2006-2007
National Academies of Sciences, Engineering, and Medicine
2007
Functionalized silver nanoparticles (NPs) were synthesized with a cyano probe and utilized to label the surface of HeLa cells expressing recombinant transmembrane domain platelet-derived growth factor receptor. Optical imaging, high-resolution Raman scanning electron microscopy (SEM) used characterize enhanced scattering (SERS) effect at cell membrane. Different assemblies NPs resulted in markedly different enhancement. We validated necessity NP aggregates polarization dependency for optimal...
Accurate methods for quantitating volatile phenols (i.e., guaiacol, syringol, 4-ethylphenol, etc.) in smoke-exposed Vitis vinifera berries prior to fermentation are needed predict the likelihood of perceptible smoke taint following vinification. Reported here is a complete, cross-validated analytical workflow accurately quantitate free and glycosidically bound using liquid-liquid extraction, acid-mediated hydrolysis, gas chromatography-tandem mass spectrometry. The reported addresses...
To analyze the naphthenic acid content of environmental waters quickly and efficiently, we have developed a method that employs differential mobility spectrometry (DMS) coupled to mass (MS). This technique combines benefits infusion-based MS experiments (parallel, on-demand access individual components) with DMS's ability provide liquid chromatography-like separations isobaric isomeric compounds in fraction time. In this study, applied DMS-MS workflow rapid gas-phase separation acids (NAs)...
Smoke-taint is a wine defect linked to organoleptic volatile phenols (VPs) in Vitis vinifera L. berries that have been exposed smoke from wildland fires. Herein, the levels of smoke-taint-associated VPs are reported Cabernet Franc veraison commercial maturity and after primary fermentation following on-vine exposure simulated fire smoke. increased were rapidly stored as acid-labile conjugates, both free conjugated forms remained constant through ripening maturity. An increase total suggested...
Plants are the main sources of many high-value bioactive terpenoids used in medical, fragrance, and food industries. Increasing demand for these plants their derivative products (e.g., cannabis extracts thereof) requires robust approaches to verify feedstock, identify product adulteration, ensure safety. Reported here single-laboratory validation details a testing method quantitate select terpenes dry plant materials terpenoid-containing vaping liquids product) using high-temperature...
Vineyard exposure to wildfire smoke can taint grapes and wine. To understand the impact of this taint, it is imperative that analytical methods used are accurate precise. This study compared variance across nine commercial research laboratories following quantitative analysis same set smoke-tainted wines. In parallel, correlations between interlaboratory consensus values for smoke-taint markers sensory analyses wines were evaluated. For free guaiacol, mean accuracy was 94 ± 11% in model...
Neonicotinoid pesticides and their metabolites have been indicated as contributing factors in the decline of honey bee colonies. A thorough understanding neonicotinoid toxicity requires knowledge environmental breakdown products. This work investigated rapid degradation nitenpyram finished drinking water.Nitenpyram reaction products were characterized using liquid chromatography/quadrupole time-of-flight mass spectrometry (LC/QTOFMS). software algorithm that compared degraded control samples...
Smoke-taint is a wine defect that may occur when ripening grape crops absorb volatile phenols (VPs), compounds associated with the negative sensory attributes of smoke-taint, due to exposure grapes wildfire smoke. This study examined potential methods reduce impact smoke-exposure has on grapes. Specifically, agricultural sprays normally used protect from fungal pathogens and spray prevent cracking in soft-fleshed fruits were assessed for their capacity inhibit increases VP concentrations...
When wine grapes are exposed to smoke, there is a risk that the resulting wines may possess smoky, ashy, or burnt aromas, flaw known as smoke taint. Smoke taint occurs when volatile phenols (VPs) largely responsible for aroma of transformed in grape into range glycosides imperceptible by smell. The majority VP-glycosides described date disaccharides possessing reducing β-d-glucopyranosyl moiety. Here, two-part experiment was performed (1) assess stability 11 synthesized towards general...
Abstract Introduction Cannabis sativa L. (cannabis) is utilised as a therapeutic and recreational drug. With the legalisation of cannabis in many countries anticipated regulation potency that will accompany legalisation, analytical testing facilities require broadly applicable, quantitative, high throughput method to meet increased demand. Current methods for biologically active components (phytocannabinoids) suffer from low and/or an incomplete complement relevant phytocannabinoids....
Raman and coherent anti-Stokes scattering (CARS) microscopies have the potential to aid in detailed longitudinal studies of RNA localization. Here, we evaluate use carbon–deuterium benzonitrile functional group labels as contrast agents for vibrational imaging hepatitis C virus (HCV) replicon RNA. Dynamic light atomic force microscopy were used structural consequences altering HCV subgenomic Modification with caused tertiary structure partially unfold. Conversely, deuterium-modified was...
Following recent studies that showed the agrochemical mepiquat (1,1-dimethylpiperidinium) forms during roasting of coffee beans and barley, this work investigates presence in malted barley commercially available beers. Liquid chromatography–tandem mass spectrometry was used to develop a sensitive precise analytical method, with detection limits 0.031 ng/g 0.014 beer. Mepiquat detected nine out 10 samples, all results under Canadian maximum residue limit (100 ng/g). The data suggest...
Owing to the lack of federal oversight recreational and medical cannabis in United States, a patchwork regulatory guidelines exists for compliance testing. Adding this complexity is fact that Canadian regulations differ from those any state mandated jurisdictions and, at time writing, was only recently legalized Mexico. Therefore, North American perspective, testing represents significant landscape navigate. This not makes things confusing involved production processing, it also creates...
With the recent legalization of cannabis in several states, there is a growing need for robust, cost-effective analytical methods to facilitate routine testing. While testing potency (and pesticide and herbicide residues) important, manufacturers products also fit-to-purpose that provide information on sensory profile their ensure lot-to-lot consistency. Here, we present an LCMS/MS method uses atmospheric pressure chemical ionization (APCI) analysis terpenes (major determinant aroma)...