A5057717728- Vestibular and auditory disorders
- Ear Surgery and Otitis Media
- Hearing Loss and Rehabilitation
- Hearing, Cochlea, Tinnitus, Genetics
- Tracheal and airway disorders
- Cerebral Venous Sinus Thrombosis
- Dysphagia Assessment and Management
- Glaucoma and retinal disorders
- Trigeminal Neuralgia and Treatments
- Ophthalmology and Eye Disorders
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Obstructive Sleep Apnea Research
- Hearing Impairment and Communication
- Otitis Media and Relapsing Polychondritis
- Facial Nerve Paralysis Treatment and Research
- Vascular Anomalies and Treatments
- Meningioma and schwannoma management
- Ear and Head Tumors
- Cardiac tumors and thrombi
- Hemispheric Asymmetry in Neuroscience
- Optical Imaging and Spectroscopy Techniques
- Reproductive System and Pregnancy
- Oral Health Pathology and Treatment
- Voice and Speech Disorders
Centre Hospitalier Universitaire de Toulouse
2014-2025
Hôpital Purpan
2020-2024
Hôpital Larrey
2023
Université Toulouse III - Paul Sabatier
2021-2023
Hôpital Paule de Viguier
2021-2022
Unité de Recherche Interdisplinaire Octogone
2021
Macrophages are essential for HIV-1 pathogenesis and represent major viral reservoirs. Therefore, it is critical to understand macrophage infection, especially in tissue macrophages, which widely infected vivo, but poorly permissive cell-free infection. Although cell-to-cell transmission of a determinant mode infection how transfers toward macrophages remains elusive. Here, we demonstrate that fusion CD4+ T lymphocytes with human leads their efficient productive Importantly, several...
In children, single-sided deafness (SSD) affects the development of linguistic and social skills can impede educational progress. These difficulties may relate to cortical changes that occur following SSD, such as reduced inter-hemispheric functional asymmetry maladaptive brain plasticity. To investigate these neuronal their evolution in a non-invasive technique is required little affected by motion artifacts. Here, we present research protocol uses near-infrared spectroscopy (fNIRS)...
Infection after cochlear implantation is a rare but serious event that can lead to meningitis. There no consensus on prevention of infection in these patients, and each center applies its own strategy.To describe the rates major surgical site for patients undergoing who receive prolonged antibiotic treatment compared with those single perioperative dose prophylaxis.Retrospective cohort study underwent between January 1, 2011, July 8, 2015, postoperative follow-up 1 3 years. In this...
To compare the outcomes of patients with unilateral otosclerosis treated consecutively by a hearing aid then stapedotomy.Monocentric, nonrandomized, prospective, longitudinal, cohort study.Tertiary university hospital.Adult conductive loss at least 30 dB caused otosclerosis.Consecutive treatment an external followed stapedotomy.Differences between aids and stapedotomy in quality life, pure-tone audiometry, binaural hearing, tinnitus severity, patient satisfaction.Twenty-two were included,...
The Deglutition Handicap Index (DHI) is a self-report measure for patients at risk of oropharyngeal dysphagia on deglutition-related aspects functional health status (FHS) and health-related quality life (HR-QoL). DHI consists 30 items which are subsumed within the Symptom, Functional Emotional subscales. purpose this study was to evaluate psychometric properties using Classic Test Theory according COnsensus-based Standards selection Measurement INstruments (COSMIN) criteria. A total 453...
A bstract Objective Different procedures have been described to treat superior canal dehiscence. The present study aims describe the results obtained with middle fossa approach, transmastoid and round window reinforcement in a large series of patients. Methods Design In this single‐center retrospective study, we report performed between 2006 2019 using three main surgical approaches, approach (MFA), (TMA), (RWR). outcome on cardinal cochlear vestibular symptoms, audiometric results, changes...
Aminoglycosides (AGs), such as tobramycin, are essential antibiotics in the management of pulmonary infections patients with cystic fibrosis (CF). They induce ototoxicity without relationship being clearly described literature. Our aim is to propose a mathematical and statistical model describing between estimated cumulative exposure (Area Under Curve, AUC) tobramycin audiogram interpretation young CF.
Multiple System Atrophy (MSA) dysphagia is routinely assessed by the Unified Rating Scale (UMSARS) part I-item 2.To compare UMSARS 2 with an ear/nose/throat (ENT) expert physician assessment.We retrospectively analyzed data of MSA patients who underwent ENT assessment (nasofibroscopic and radioscopic exam) annual assessment. Deglutition Handicap Index (DHI) pulmonary/nutrition complications were collected.Seventy-five included. The revealed more severe compared to score (P = 0.003). A higher...
ABSTRACT Background High‐dose chemotherapy (HDCT) with TI‐CE regimen is a valid option for the treatment of relapsed advanced germ cell tumors (GCT). We report phase II trial therapeutic drug monitoring carboplatin optimizing area under curve (AUC) this drug. Methods Patients unfavorable GCT were treated according to regimen: two cycles combining paclitaxel and ifosfamide followed by three HD plus etoposide administered on 3 days. Carboplatin dose was adapted day based clearance (CL) at 1 in...
Menière's disease (MD) still presents both diagnostic and therapeutic difficulties. Today, this pathology is diagnosed only on clinical criteria. The development of high resolution magnetic resonance imaging the inner very promising to improve criteria in MD. MD treatment depending practitioner center, mainly based conservative therapies, if fails, non-ablative or ablative therapies. therefore always exposes clinicians uncertainties, but also difficulties which lead destructive treatments,...