Alice Galzignato

ORCID: 0000-0003-3198-9694
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About
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Research Areas
  • Corneal surgery and disorders
  • Ophthalmology and Visual Impairment Studies
  • Glaucoma and retinal disorders
  • Retinal Diseases and Treatments
  • Ocular Diseases and Behçet’s Syndrome
  • Retinal Development and Disorders
  • Intraocular Surgery and Lenses
  • Ocular Infections and Treatments
  • Ocular Surface and Contact Lens
  • Phytochemistry and Biological Activities
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • RNA regulation and disease
  • Retinal and Optic Conditions
  • Optical Coherence Tomography Applications
  • Mitochondrial Function and Pathology
  • Cellular transport and secretion
  • Lysosomal Storage Disorders Research
  • Retinoids in leukemia and cellular processes
  • Corneal Surgery and Treatments
  • melanin and skin pigmentation
  • Cerebral Venous Sinus Thrombosis
  • Protein Tyrosine Phosphatases

Lundbeck (Italy)
2022

University of Verona
2020-2021

PURPOSE: To evaluate and compare the objective subjective outcomes between bilateral implantation of extended depth focus (EDOF) Mini Well intraocular lens (IOL) aspheric monofocal Mini-4-Ready IOL (both SIFI S.p.A., Catania, Italy). METHODS: This prospective comparative study included 25 patients (50 eyes) bilaterally implanted with an EDOF (EDOF group) a (monofocal group). Three-month follow-up data corrected uncorrected distance visual acuity at 4 m 80, 67, 40 cm. Defocus curves, contrast...

10.3928/1081597x-20200212-01 article EN Journal of Refractive Surgery 2020-04-01

To evaluate the repeatability of measurements provided by a new optical biometer (EyeStar 900) based on swept-source coherence tomography (SS-OCT) and their agreement with given 2 validated biometers same technology, IOLMaster 700 Argos.IRCCS G.B. Bietti Foundation, Rome, Italy.Prospective evaluation diagnostic test.In series unoperated eyes, 3 consecutive scans were acquired EyeStar 900, 1 Argos. The following biometry parameters analyzed: axial length (AL), keratometry (K), corneal...

10.1097/j.jcrs.0000000000001023 article EN Journal of Cataract & Refractive Surgery 2022-08-26

Aims/Purpose: Characterization of Visual Field (VF) loss patterns chronic stage Leber Hereditary Optic Neuropathy (LHON) patients by application machine learning (ML). Methods: For stable LHON patient, at least 2 years after disease onset, 24‐2 and 30‐2 VFs tests performed SITA standard Humphrey VF analyzer (Carl Zeiss Meditec) were collected. Two groups considered: with visual acuity (VA) recovery, when a change more than 0.2 decimal or from off‐chart to on‐chart vision initial vision;...

10.1111/aos.17016 article EN Acta Ophthalmologica 2025-01-01

Aims/Purpose: To study the optic nerve head (ONH) dimension in symptomatic and asymptomatic patients with Leber hereditary neuropathy (LHON) to correlate ONH parameters genotype clinical phenotype. Methods: Seventy‐eight affected patients, 175 carriers, 29 age‐matched healthy controls were enrolled study. All underwent optical coherence tomography (OCT) measurements by DRI OCT Triton (Topcon, Japan) analyzed Orion custom software (Volexeron, CA, USA). The following obtained for each eye:...

10.1111/aos.17147 article EN Acta Ophthalmologica 2025-01-01

Aims/Purpose: Characterization of Visual Field (VF) loss patterns chronic stage Leber Hereditary Optic Neuropathy (LHON) patients by application machine learning (ML). Methods: For stable LHON patient, at least 2 years after disease onset, 24‐2 and 30‐2 VFs tests performed SITA standard Humphrey VF analyzer (Carl Zeiss Meditec) were collected. Two groups considered: with visual acuity (VA) recovery, when a change more than 0.2 decimal or from off‐chart to on‐chart vision initial vision;...

10.1111/aos.17183 article EN Acta Ophthalmologica 2025-01-01

Abstract Background To investigate the functional results of AcrySof IQ Vivity (Alcon, Fort Worth, TX) extended depth-of-focus intraocular lens (EDoF-IOL) and explore correlations between preoperative biometric parameters postoperative outcomes. Methods In a prospective, single-center, non-randomized study, axial length, keratometry, anterior chamber depth, scotopic photopic pupil diameters, decentration, corneal asphericity, higher-order aberrations (HOAs), coma spherical aberration were...

10.1186/s40662-024-00424-y article EN cc-by Eye and Vision 2025-02-02

Purpose: To evaluate the repeatability of measurements obtained with a new spectral-domain optical coherence tomography-based biometer (Colombo IOL II, Moptim) and assess their agreement those provided by IOLMaster 700 (Zeiss). Setting: I.R.C.C.S. Bietti Foundation, Rome, Italy. Design: Prospective evaluation diagnostic test. Methods: Patients underwent 3 consecutive scans Colombo II 1 700. Two groups were analyzed: Group A included series patients undergoing phacoemulsification B subjects...

10.1097/j.jcrs.0000000000001650 article EN Journal of Cataract & Refractive Surgery 2025-03-10

To evaluate objective and subjective outcomes after bilateral implantation of two different multifocal intraocular lenses, which correct pseudophakic presbyopia in an adequate homogeneous population court.Fifty patients were evaluated at 3 months implantation, the Eye Clinic University Verona Carones Ophthalmology Center Milano, as follows: Tecnis Symfony (25 patients), Alcon PanOptix patients). Main uncorrected best-corrected distance visual acuity (UDVA BCVA) 4 m, 60 cm (best corrected...

10.1136/bmjophth-2020-000497 article EN cc-by-nc BMJ Open Ophthalmology 2020-10-01

PurposeThis study aimed to explore the concept of total keratometry (TK) by analyzing extensive international datasets representing diverse ethnic backgrounds. The primary objective was quantify disparities between traditional (K) and TK values in normal eyes assess their impact on intraocular lens (IOL) power calculations using various formulas.DesignRetrospective multicenter intra-instrument reliability analysis.MethodsThe involved analysis biometry data collected from ten centers across...

10.1016/j.ajo.2023.12.003 article EN cc-by American Journal of Ophthalmology 2023-12-12

Purpose: Dominant optic atrophy (DOA) is an inherited condition caused by autosomal dominant mutations involving the OPA-1 gene. The aim of this study was to assess relationship between macular ganglion cell and inner plexiform layer (GC-IPL) thickness obtained from structural optical coherence tomography (OCT) visual outcomes in DOA patients. Methods: recruited 33 patients with confirmed heterozygous mutation DOA. OCT scans were conducted measure GC-IPL thickness. average sectorial Early...

10.1167/iovs.65.1.24 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2024-01-09

Refractive surgery is one of the most common elective surgeries performed worldwide. The incidence dry eye disease (DED) after corneal refractive varies among different studies. Pre-existing untreated DED has been identified as a risk factor for postsurgical symptoms. On basis both evidence and clinical experience, some recommendations ocular surface management pre- post-refractive are described. In aqueous deficiency Dry Eye Disease, preservative-free lubricating drops should be preferred,...

10.1177/11206721231176312 article EN European Journal of Ophthalmology 2023-05-22

To compare the objective and subjective outcomes between extended depth of focus (EDOF) Mini Well intraocular lens (IOL) aspheric monofocal Mini-4-Ready IOL (both SIFI S.p.A.) in patients with high myopia.In this prospective comparative study, 40 myopia (axial length ≥ 26 mm) were enrolled: 20 bilaterally implanted EDOF (EDOF group) (monofocal group). Three-month follow-up data included corrected uncorrected distance visual acuity at 4 m 80, 67, cm, defocus curves, contrast sensitivity,...

10.3928/1081597x-20211220-01 article EN Journal of Refractive Surgery 2022-03-01

Aims/Purpose: Identification of the characteristic visual field loss patterns dominant optic atrophy (DOA) employing Archetypal Analysis (AA) machine learning algorithm and further relation with patient‐specific parameters. Methods: For 64 patients affected by molecularly confirmed DOA OPA1 heterozygous mutation, binocular (VF) tests performed SITA standard 30–2 or 24–2 Humphrey VF analyser (Carl Zeiss Meditec, Dublin, CA, USA) were collected. that had multiple tests, several VFs collected...

10.1111/aos.16115 article EN Acta Ophthalmologica 2024-01-01

Aims/Purpose: To study the optic nerve head (ONH) dimension in symptomatic and asymptomatic patients with Leber hereditary neuropathy (LHON) to correlate ONH parameters genotype clinical phenotype. Methods: Seventy‐eight affected patients, 175 carriers, 29 age‐matched healthy controls were enrolled study. All underwent optical coherence tomography (OCT) measurements by DRI OCT Triton (Topcon, Japan) analysed Orion custom software (Volexeron, CA, USA). The following obtained for each eye:...

10.1111/aos.16118 article EN Acta Ophthalmologica 2024-01-01

Aims/Purpose: Identification and quantification of visual field loss patterns dominant optic atrophy forms ( ACO2 AFG3L2 mutations) recessive form WFS1 mutation, Wolfram Syndrome, WS) based on machine learning‐obtained archetypes for OPA1 ‐Dominant Optic Atrophy (DOA). Methods: Five patients affected by hereditary neuropathies carrying gene mutations, 5 with 20 mutations were enrolled. Visual (VF) tests performed SITA standard 30–2 or 24–2 Humphrey VF analyzer (Carl Zeiss Meditec, Dublin,...

10.1111/aos.16108 article EN Acta Ophthalmologica 2024-01-01

Background: this retrospective study aimed to analyze the results of combination Haigis formula and Total Keratometry (TK) calculate IOL power in eyes with previous corneal refractive surgery. Methods: The TK value provided by Master 700 (Carl Zeiss Meditec) was introduced into formula; mean prediction error (PE), absolute (MAE), median (MedAE) percentage a PE within ±0.25 D, ±0.5 ±0.75 D ±1.00 were calculated. Results: Ninety-three 93 patients laser surgery evaluated. Two groups defined:...

10.20944/preprints202304.1231.v1 preprint EN 2023-04-29

Background: this retrospective study aimed to analyze the results of combination Haigis formula and total keratometry (TK) in calculating IOL power eyes with previous corneal refractive surgery. Methods: TK value provided by Master 700 (Carl Zeiss Meditec) was introduced into formula; mean prediction error (PE), absolute (MAE), median (MedAE) percentage a PE within ±0.25 D, ±0.5 ±0.75 D ±1.00 were calculated. Results: ninety-three 93 patients laser surgery evaluated. Two groups defined:...

10.3390/photonics10060624 article EN cc-by Photonics 2023-05-28
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