A5064005415- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Neurogenetic and Muscular Disorders Research
- Retinal Development and Disorders
- Systemic Lupus Erythematosus Research
- RNA modifications and cancer
- Drug-Induced Ocular Toxicity
- Ubiquitin and proteasome pathways
- Coordination Chemistry and Organometallics
- Endoplasmic Reticulum Stress and Disease
- Autoimmune and Inflammatory Disorders Research
- Cardiac tumors and thrombi
- Connective tissue disorders research
- Cancer, Hypoxia, and Metabolism
- Otitis Media and Relapsing Polychondritis
- Fibroblast Growth Factor Research
- Amyotrophic Lateral Sclerosis Research
- Optical Coherence Tomography Applications
- Genetic and Kidney Cyst Diseases
- Congenital Anomalies and Fetal Surgery
- Mitochondrial Function and Pathology
- RNA regulation and disease
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2025
Vita-Salute San Raffaele University
2021-2025
IRCCS Ospedale San Raffaele
2022-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2021-2024
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2023
Azienda Ospedaliero Universitaria Maggiore della Carita
2023
San Raffaele University of Rome
2022
Università Cattolica del Sacro Cuore
2019
Purpose: To estimate the impact of transition from intermediate to exudative neovascular age-related macular degeneration (AMD) on inner retina and assess relationship clinical characteristics optical coherence tomography (OCT) findings with retinal changes. Methods: A total 80 participants (80 eyes) AMD at baseline who developed within 3 months were included in analysis. OCT scans follow-up visits (after AMD) compared values latest visit evidence quantify longitudinal images also reviewed...
Purpose: To explore the occurrence of macular atrophy (MA) in eyes with age-related degeneration (AMD)-associated Type 3 neovascularization (MNV) treated anti-vascular endothelial growth factor (anti-VEGF) therapy. Importantly, we aimed at describing existence separate pathways leading to MA. Methods: We analyzed 41 participants (41 eyes) treatment-naïve MNV who were followed up for a duration 12 months after beginning anti-VEGF At one-year follow-up visit, optical coherence tomography (OCT)...
The purpose of this study was to investigate a confocal scanning laser ophthalmoscopy (cSLO) ultra-widefield (UWF) swept-source optical coherence tomography (S-SOCT) in assessment diabetic choroidopathy and evaluate the agreement measurements with spectral-domain OCT (SD-OCT) instrument.We conducted cross-sectional patients diabetes evaluating choroidal vascularity index (CVI) nasal, temporal, central macula segments UWF SS-OCT scan centered fovea. pseudocolored fundus images were used for...
To assess the relationship of optical coherence tomography (OCT) findings and progression to foveal atrophy in a cohort eyes with extrafoveal geographic (GA) age-related macular degeneration (AMD) at inclusion.
Abstract Background To perform a three-dimensional assessment of the choroid, including choroidal volume and vascularity index (CVI), during transition from intermediate to neovascular age-related macular degeneration (AMD), following anti-VEGF therapy. Methods A total 42 participants (42 eyes) with AMD at baseline who developed within 3 months were included in analysis. Optical coherence tomography (OCT) scans follow-up visits (after 12 after initiation therapy) compared values latest visit...
Purpose Uveitis embraces a heterogeneous group of vision-threatening inflammatory conditions. Understanding uveitis epidemiology, etiology, and clinical findings is fundamental for prompt diagnosis optimal patient management. The aim the study to report epidemiology in national referral center Northern Italy investigate visual prognosis.
The aim of this study was to assess the relationship clinical characteristics rate retinal thinning in eyes with diabetic macular edema (DME) treated anti-vascular endothelial growth factor (VEGF) therapy. We analyzed subjects a long-term follow-up (≥ 3 years) and evidence resolved DME after initiation anti-VEGF therapy (baseline visit). To measure during treatment, second visit (first also considered. A longitudinal quantitative topographical assessment inner outer thicknesses provided....
Purpose: The purpose of this study was to describe the presence choroidal hyper-reflective foci (HRF) on optical coherence tomography (OCT) in patients with geographic atrophy (GA). relationship between and quantity HRF other clinical imaging factors also investigated. Methods: A total 40 participants (40 eyes) GA age-related macular degeneration (AMD) were retrospectively analyzed. OCT images reviewed for presence, characteristics, localization HRF. amount quantified different layers by two...
Macular neovascularization (MNV) is a common complication of age-related macular degeneration (AMD). Although several biomarkers may help to estimate the risk MNV onset, neovascular difficult predict. Previous studies showed that quantitative assessment choroidal and choriocapillaris changes useful for atrophy expansion. On other hand, scant data are available regarding role this kind in setting MNV. The aim study analyze occurring before onset patients affected by AMD using optical...
Macular neovascularization (MNV) secondary to age-related macular degeneration (AMD) is well managed by anti-vascular endothelial growth factor (anti-VEGF) intravitreal injections. However, outer retinal atrophy represents an unavoidable occurrence detected during follow-up. Several imaging metrics have been proposed as clinically relevant in stratifying the risk of onset atrophy. The main goal this study evaluate impact noninvasive on assessment a large cohort eyes with neovascular AMD...
Purpose: To investigate the relationship between retinal structure and macular function in eyes screened for hydroxychloroquine (HCQ) toxicity. Methods: Participants referred retinopathy screening with spectral domain optical coherence tomography (SD-OCT) multifocal electroretinogram (mfERG) testing were included analysis. Amplitude implicit time of mfERG N1 P1 responses Ring ratios computed amplitude values as ratio rings 1–3:5 (R1–3:R5). A control group healthy participants was comparison...
(1) Purpose: To determine the “retinal thickness deviation” (RTD) in diabetic macular edema (DME) eyes treated with intravitreal therapy and to establish associations between RTD best-corrected visual acuity (BCVA). (2) Methods: We conducted a retrospective study, including consecutive patients DME undergoing two years of follow-up. BCVA central subfield (CST) were collected at baseline 12 months 24 was calculated as absolute difference measured normative CST values each time point. Linear...
To assess relationships between demographics, clinical characteristics, and optical coherence tomography characteristics with persistence of metamorphopsia after resolution subretinal fluid in eyes chronic central serous chorioretinopathy.One-hundred participants "resolved" (absence fluid) chorioretinopathy were retrospectively analyzed. Patients underwent a complete ophthalmologic evaluation, including assessment the presence metamorphopsia. At study visit, scans reviewed for qualitative...
To quantitatively evaluate the inner and outer choroidal changes in fellow eyes of patients with unilateral central serous chorioretinopathy (CSC).We analyzed data from a diagnosis CSC who had structural optical coherence tomography (OCT) swept-source OCT angiography obtained. An additional group age-matched healthy was included for comparison. The main outcome measures were: (1) choriocapillaris flow deficits' quantitative metrics; (2) luminal (LCA) stromal (SCA) areas; (3) vascularity...