A5059915186- Retinal Diseases and Treatments
- Retinal and Macular Surgery
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Vascular Malformations Diagnosis and Treatment
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Impairment Studies
- Ocular Oncology and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Retinopathy of Prematurity Studies
- Trypanosoma species research and implications
- Neurological Disorders and Treatments
- Biomedical Research and Pathophysiology
- Calcium signaling and nucleotide metabolism
- Allergic Rhinitis and Sensitization
- Cerebral Venous Sinus Thrombosis
- Intraoperative Neuromonitoring and Anesthetic Effects
- Ocular Diseases and Behçet’s Syndrome
- Lysosomal Storage Disorders Research
- Acute Ischemic Stroke Management
University of Turin
2018-2025
Piedmont Reference Center for Epidemiology and Cancer Prevention
2024-2025
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2020
Purpose: The purpose of this study was to provide a topographical assessment macular atrophy in successfully treated neovascular age-related degeneration (AMD) eyes investigate determinants monocular reading performance. Methods: A total 60 participants (60 eyes) with previously AMD and absence optical coherence tomography (OCT) signs exudation were enrolled. Reading performance assessed monocularly using Radner charts. following variables obtained: (i) the acuity defined as logarithm...
The study aims to quantify the incidence of ocular complications in patients irradiated on head and neck area our medical center, stratified by type neoplasm radiation dose received.From an existing database radio-treated we selected 25 2011-2018 period. had been treated for orbital lymphoma, nasopharyngeal carcinoma cranial base meningioma. received ophthalmologic evaluation which included a complete ophthalmological orthoptic assessment.Our results showed significantly higher DES (dry eye...
To compare the number of eye surgical procedures performed in Italy 2 months following beginning lockdown (study period) because COVID-19 epidemic with those two earlier same year (intra-year control) and period 2019 corresponding to (inter-year control).Retrospective analysis carried out at 39 Academic hospitals. A distinction was made between elective urgent procedures. Intravitreal injections were also considered. Percentages for all incidence rate ratios (IRR) rhegmatogenous retinal...
Purpose To develop and validate a deep learning model for the segmentation of five retinal biomarkers associated with neovascular age-related macular degeneration (nAMD). Methods 300 optical coherence tomography volumes from subject eyes nAMD were collected. Images manually segmented presence crucial features: intraretinal fluid, subretinal hyperreflective material, drusen/drusenoid pigment epithelium detachment (PED) PED. A architecture based on U-Net was trained to perform automatic these...
Background and Objectives: Age-related macular degeneration (AMD) remains a leading cause of legal blindness. Anti-Vascular Endothelial Growth Factor (VEGF) agents are the first-line treatment for neovascular AMD (nAMD). The choroid plays key role in is affected by anti-VEGF treatment. Faricimab, bispecific antibody additionally targeting angiopoietin 2 (Ang2), was recently approved nAMD This study investigates effect Faricimab on choroidal flow signal. Materials Methods: Optical coherence...
Purpose: To explore the occurrence of macular atrophy (MA) in eyes with age-related degeneration (AMD)-associated Type 3 neovascularization (MNV) treated anti-vascular endothelial growth factor (anti-VEGF) therapy. Importantly, we aimed at describing existence separate pathways leading to MA. Methods: We analyzed 41 participants (41 eyes) treatment-naïve MNV who were followed up for a duration 12 months after beginning anti-VEGF At one-year follow-up visit, optical coherence tomography (OCT)...
This study assessed the European School of Advanced Studies in Ophthalmology (ESASO) classification's prognostic value for diabetic macular edema (DME) predicting intravitreal therapy outcomes. In this retrospective, multicenter study, patients aged > 50 years with type 1 or 2 diabetes and DME received antivascular endothelial growth factor (anti-VEGF) agents (ranibizumab, bevacizumab, aflibercept) steroids (dexamethasone). The primary outcome was visual acuity (VA) change post-treatment,...
Purpose: To compare conventional internal limiting membrane (ILM) peeling versus inverted flap technique in small-to-medium idiopathic macular hole. Methods: Eyes with ≤400 μ m holes were randomized into the ILM group (25 eyes) and eyes). A 12-month follow-up was considered. Macular sensitivity (MS) change detected MP-1 microperimetry primary outcome. Secondary outcomes included best-corrected visual acuity change, closure rate, anatomical findings on optical coherence tomography such as...
Purpose: This study aimed to comprehensively assess visual performance in eyes with idiopathic epiretinal membrane (iERM). Additionally, it sought explore the associations between optical coherence tomography (OCT) imaging biomarkers and patients iERM. Methods: In this prospective, non-interventional study, 57 participants treatment-naïve iERM from University of Turin, September 2023 March 2024 were enrolled. Visual was measured using distance best-corrected acuity (BCVA), near BCVA, maximum...
Background: To assess the outcome of Keraring (Mediphacos, Brazil) implantation according to a topographic pattern-based nomogram in eyes with mild moderate keratoconus. Materials and Methods: A was used guide selection 47 consecutive stage I-II keratoconus (Amsler-Krumeich staging), which underwent femtosecond laser-assisted at single center. Electronic data LogMar uncorrected distance visual acuity (UDVA) corrected (CDVA) manifest refraction tomographic analysis (Pentacam HR, Oculus,...
To compare intravitreal aflibercept alone versus combined with oral anti-inflammatory supplementation in patients diabetic macular edema (DME). A prospective, randomized study included 134 treatment-naive eyes central-involving DME. Participants were assigned to receive either (Group A) or Lenidase® B, containing baicalin, bromelain, and escin). Both groups followed a treat-and-extend (T&E) regimen. The primary outcome was the number of injections over 24 months. Secondary outcomes changes...
Background: Artificial iris (AI) implantation is an innovative and increasingly utilized surgical procedure for injured eyes with trauma. Methods: A 76-year-old female a 34-year-old male presented at the emergency department traumatic corneo-scleral laceration perforated corneal ulcer, respectively. Emergency surgeries were performed to restore ocular integrity. In both cases, modified technique involving of AI was performed; however, two different models used. Results: The AIs sutured four...
Purpose To evaluate macular and peripapillary microvascular changes after proton beam radiotherapy for iris melanoma using optical coherence tomography angiography (OCT-A). Methods Patients treated with were included in the group. Fellow eyes used as controls. Vessel density (VD) of superficial capillary plexus (SCP) deep (DCP) macula, radial (RPCP) foveal avascular zone (FAZ) evaluated OCT-A. Central thickness (CMT) nerve fiber layer (RNFL) also investigated. Results A total 11 patients...
Purpose To explore the factors and frequency of interruptions in intravitreal treatment for patients with neovascular age-related macular degeneration (AMD) to evaluate demographic clinical linked reasons discontinuation. Methods In this multicentre study, who began anti-vascular endothelial growth factor (VEGF) between January 2019 December 2021 treatment-naïve exudative AMD were retrospectively analysed. The overall incidence discontinuation, along rates each specific cause, was...
Purpose: to present a case of active neovascular AMD treated with anti-VEGF drug in the presence silicone oil. Study design: report. Results: A 69-year-old male was referred surgical retina service due sudden loss peripheral vision left eye (LE). Biomicroscopic examination revealed geographic atrophy right (RE) and macula-on retinal detachment far periphery drusen at posterior pole LE. Combined OCT-OCTA demonstrated non-active type 1 MNV The patient underwent 25-gauge pars plana vitrectomy...